Results 71 to 80 of about 506,753 (297)

Lack of reproducibility of trial sequential analyses: a meta-epidemiological study

open access: yesTrials
Systematic reviews and meta-analyses are essential tools for synthesizing evidence from multiple studies. Recently, trial sequential analyses (TSAs) have gained popularity as a component of meta-analyses, helping researchers dynamically monitor evidence ...
Xing Xing   +4 more
doaj   +1 more source

The clinical efficacy of intravenous IgM-enriched immunoglobulin (pentaglobin) in sepsis or septic shock: a meta-analysis with trial sequential analysis

open access: yesAnnals of Intensive Care, 2019
Background Sepsis is characterized by a complex immune response. This meta-analysis evaluated the clinical effectiveness of intravenous IgM-enriched immunoglobulin (IVIgGM) in patients with sepsis and septic shock.
Jie Cui   +6 more
doaj   +1 more source

Corrected confidence intervals for secondary parameters following sequential tests

open access: yes, 2006
Corrected confidence intervals are developed for the mean of the second component of a bivariate normal process when the first component is being monitored sequentially.
Coad, D. S., Weng, R. C.
core   +1 more source

The programming of sequences of saccades [PDF]

open access: yes, 2019
Saccadic eye movements move the high-resolution fovea to point at regions of interest. Saccades can only be generated serially (i.e., one at a time). However, what remains unclear is the extent to which saccades are programmed in parallel (i.e., a series
A Mokler   +45 more
core   +3 more sources

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu   +20 more
wiley   +1 more source

Prophylactic antibiotics in laparoscopic cholecystectomy: Reducing postoperative infection risk–A meta-analysis and trial sequential analysis

open access: yesHeliyon
Background: The impact of prophylactic antibiotics on postoperative infection following laparoscopic cholecystectomy remains controversial. This meta-analysis and trial sequential analysis aims to assess the efficacy of prophylactic antibiotics in ...
Shufeng Wang   +4 more
doaj   +1 more source

Long-Term Efficacy of Maintenance Therapy for Multiple Myeloma: A Quantitative Synthesis of 22 Randomized Controlled Trials

open access: yesFrontiers in Pharmacology, 2018
We aimed to quantitatively synthesize data from randomized controlled trials (RCTs) concerning maintenance for multiple myeloma (MM). We searched electronic literature databases and conference proceedings to identify relevant RCTs.
Jie-Li Li   +10 more
doaj   +1 more source

Toxicity Analysis in the ADEBAR Trial: Sequential Anthracycline-Taxane Therapy Compared with FEC120 for the Adjuvant Treatment of High-Risk Breast Cancer [PDF]

open access: yes, 2012
Background: Data from meta-analyses have shown taxane-containing therapies to be superior to anthracycline-based treatments for high-risk breast cancer. Patients and Methods: The ADEBAR trial was a multicenter phase Ill trial in which patients with lymph
Aivazova-Fuchs, Viktoria   +16 more
core   +1 more source

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül   +2 more
wiley   +1 more source

Low-Volume Polyethylene Glycol Improved Patient Attendance in Bowel Preparation Before Colonoscopy: A Meta-Analysis With Trial Sequential Analysis

open access: yesFrontiers in Medicine, 2019
Background: Polyethylene glycol (PEG) has been regarded as the primary recommendation for bowel preparation before colonoscopy. However, a conclusive conclusion has not yet been generated.Aim: We performed this updated meta-analysis to further ...
Li-Juan Yi   +12 more
doaj   +1 more source

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