Results 31 to 40 of about 2,405 (150)

Caveolae-dependent endocytosis mediates the cellular uptake of CdTe quantum dots in ovarian cancer cell lines

open access: yesResearch in Pharmaceutical Sciences, 2022
Background and purpose: Quantum dots (QDs) are semiconductor nanocrystals that are widely used in biology due to their good optical properties. QDs, especially cadmium-based QDs, play an important role in the diagnosis and treatment of cancer due to ...
Zahra Asadian   +3 more
doaj   +1 more source

Univariate versus multivariate spectrophotometric data analysis of triamterene and xipamide; a quantitative and qualitative greenly profiled comparative study

open access: yesBMC Chemistry, 2023
Triamterene (TRI) and xipamide (XIP) mixture is used as a binary medication of antihypertension which is considered as a major cause of premature death worldwide.
Heidi R. Abd El-Hadi   +3 more
doaj   +1 more source

Computational screening of FDA-approved drugs to identify potential TgDHFR, TgPRS, and TgCDPK1 proteins inhibitors against Toxoplasma gondii

open access: yesScientific Reports, 2023
Toxoplasma gondii (T. gondii) is one of the most successful parasites in the world, because about a third of the world's population is seropositive for toxoplasmosis. Treatment regimens for toxoplasmosis have remained unchanged for the past 20 years, and
Zahra Gharibi   +5 more
doaj   +1 more source

Sodium Channel Blockers Demonstrate Binding Affinity for the Tandem Tudor Domain of the Epigenetic Hub UHRF1

open access: yesChemMedChem, Volume 21, Issue 17, 14 September 2026.
An investigation of the tandem Tudor domain (TTD) domain of UHRF1 identified and extensively characterized the local anesthetic hydroxyprocaine as a strong ligand capable of activating related genes such as p53 and also highlighted a new, potentially druggable intramolecular interaction between TTD and UBL.
Efstratios Tsakalidis   +16 more
wiley   +1 more source

Kidney Stone, Nutritional Perceptions and Impact of Tea on Stone Formation

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
ABSTRACT The significant financial burden that urinary stone disease places on healthcare systems is only anticipated to increase over time. It is becoming more common over the globe. It is an increasing urinary condition that impacts around 12% of the global population, and environmental variables appear to be a key contributor.
Munir Ahmed   +5 more
wiley   +1 more source

Proteolytic Activation of the Epithelial Sodium Channel in Nephrotic Syndrome by Proteasuria: Concept and Therapeutic Potential

open access: yesTurkish Journal of Nephrology, 2020
The epithelial sodium channel (ENaC) is expressed in the aldosterone-sensitive distal nephron, and it determines the final urinary sodium concentration.
Ferruh Artunç
doaj   +1 more source

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

open access: yesDrug Testing and Analysis, Volume 18, Issue 4, Page 458-482, April 2026.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 228-240, January 2026.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan   +6 more
wiley   +1 more source

Sex differences in blood pressure hemodynamics and white matter hyperintensity volume across racial ethnic groups—HABS‐HD

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 1, January/March 2026.
Abstract INTRODUCTION It remains unclear whether specific blood pressure components—systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse pressure (PP), or mean arterial pressure (MAP)—are similarly associated with white matter hyperintensity (WMH) burden across sexes within racial and ethnic groups.
Cellas A. Hayes   +3 more
wiley   +1 more source

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