Results 41 to 50 of about 2,405 (150)

Diuretics and Hypokalemia [PDF]

open access: yesActa Medica Iranica, 1970
We have studied hypokalemic action of different diuretics in a cooperative study on 28 patients and our results are as follows: I. 28 patients (18 male and 10 female) were the subject of our present study. 2. E. C. G.
Ali A. Handjani   +2 more
doaj   +2 more sources

A double‐blind, placebo‐controlled trial on the antihypertensive treatment effect of a quadruple single‐pill combination

open access: yesThe Journal of Clinical Hypertension, 2021
In a randomized, double‐blind, placebo‐controlled trial, we investigated antihypertensive treatment effect of a quadruple single‐pill combination of reserpine 0.1 mg, dihydralazine 12.5 mg, hydrochlorothiazide 12.5 mg, and triamterene 12.5 mg, and ...
Lei‐Xiao Hu   +8 more
doaj   +1 more source

Investigation of triamterene as an inhibitor of the TGR5 receptor: identification in cells and animals

open access: yesDrug Design, Development and Therapy, 2017
Yingxiao Li,1,2 Kai Chun Cheng,1 Chiang-Shan Niu,3 Shih-Hsiang Lo,3,4 Juei-Tang Cheng,2,5 Ho-Shan Niu31Department of Psychosomatic Internal Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan; 2Department of ...
Li Y   +5 more
doaj  

A Case of Recurrent Renal Aluminum Hydroxide Stone

open access: yesCase Reports in Urology, 2014
Renal stone disease is characterized by the differences depending on the age, gender, and the geographic location of the patients. Seventy-five percent of the renal stone components is the calcium (Ca).
Basri Cakıroglu   +4 more
doaj   +1 more source

Liddle′s syndrome: A case report

open access: yesSaudi Journal of Kidney Diseases and Transplantation, 2015
Liddle′s syndrome or pseudoaldosteronism is a rare autosomal dominant disease mimicking primary hyperaldosteronism, characterized by early-onset hypertension, hypokalemia and hypoaldosteronism, caused by excessive salt and water reabsorption in the ...
Pranav Patel, Reena Kuriacose
doaj   +1 more source

Screening and Diagnosis of Primary Aldosteronism in Patients Using Renin‐Angiotensin System Inhibitors

open access: yesThe Journal of Clinical Hypertension, Volume 28, Issue 1, January 2026.
ABSTRACT This study investigated whether patients receiving renin‐angiotensin system inhibitors (RASIs) can undergo reliable screening for primary aldosteronism (PA) without discontinuation of therapy. Consecutive patients with hypertension who underwent PA screening at our hospital between 2016 and 2024 while on RASIs were recruited.
Qian Wang   +4 more
wiley   +1 more source

Joint Effects of Anticholinergic Burden and Neurofilament Light on Dementia Risk: The Shanghai Aging Study

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
The combined ACD use and elevated NfL levels jointly increased the risk of incident dementia. Older adults with both high ACDs exposure and high NfL levels exhibited a significantly higher risk of dementia compared to low‐burden counterparts. ABSTRACT Aims Anticholinergic drugs (ACDs) and the neurodegeneration biomarker neurofilament light chain (NfL ...
Danyi Chi   +6 more
wiley   +1 more source

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1463-1476, December 2025.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu   +21 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +86 more
wiley   +1 more source

7‐Ketodeoxycholic Acid Promotes Colonic Mucosal Healing by Inducing Calcium Release from Endoplasmic Reticulum via the TGR5‐IP3R Pathway

open access: yesAdvanced Science, Volume 12, Issue 42, November 13, 2025.
7‐KDCA functions by driving intestinal epithelial cell migration through induction of calcium release from the endoplasmic reticulum. The findings emphasize a previously unrecognized property of 7‐KDCA in regulating cell migration, a required process for effective epithelial restitution and repair that is particularly critical for patients with UC to ...
Jing Zhang   +9 more
wiley   +1 more source

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