Results 31 to 40 of about 344,663 (315)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Mariangela in Verga’s La caccia al lupo: From Page to Stage
Between, 2013 This article considers the transposition from short story into play of Giovanni Verga’s La caccia al lupo. This pair of texts has been studied less than Cavalleria rusticana and La Lupa,and therefore the present discussion aims to contribute to existing ...
Enza De Francisci
doaj +1 more source
Rainbow triangles in families of triangles
, 2022 7 pages, 5 figures.
Goorevitch, Ido, Holzman, Ron
openaire +2 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Translative Covering a Square with Isosceles Right Triangles
GeometryA translative covering the rectangle a×b with homothetic copies of a right isosceles triangle T (of the legs parallel to the sides of a×b) is considered.
Janusz Januszewski, Łukasz Zielonka
doaj +1 more source
, 2014 A binary CSP instance satisfying the broken-triangle property (BTP) can be solved in polynomial time. Unfortunately, in practice, few instances satisfy the BTP. We show that a local version of the BTP allows the merging of domain values in binary CSPs, thus providing a novel polynomial-time reduction operation.
Martin C. Cooper +3 more
openaire +4 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
La Fausse Suivante, ou la dynamique du triangle [PDF]
Çédille: Revista de Estudios Franceses, 2009 The dramaturgy of Marivaux’s comedy La Fausse Suivante weaves the relationships of its characters into a triangular shape. It isa changing inter-action due to the presence of masks hiding their truth. This system of unstable triangles’ axis is the triple
María Teresa Ramos Gómez
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
SEEU Review, 2017 The Republic of Macedonia (RM) has been a part of the Bologna process since 2003. The Ministry of Education, law and policy makers and higher education institutions have actively engaged with its main concepts.
Veronika Kareva +3 more
doaj +1 more source