Results 41 to 50 of about 401,052 (253)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Static 3D Triangle Mesh Compression Overview [PDF]

, 2008
3D triangle meshes are extremely used to model discrete surfaces, and almost always represented with two tables: one for geometry and another for connectivity.
Marcos Aviles, Avilés Rodrigálvarez, Marcos, Morán Burgos, Francisco, Francisco Moran   +3 more
core   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

BERPIKIR SISWA SMP DALAM MENYELESAIKAN SOAL SEGITIGA DITINJAU DARI GEOMETRIC HABITS OF MIND [MIDDLE SCHOOL STUDENTS' THINKING IN SOLVING TRIANGLE PROBLEMS FROM THE PERSPECTIVE OF GEOMETRIC HABITS OF MIND]

JOHME: Journal of Holistic Mathematics Education
Understanding student thinking is important, especially regarding triangle material as it is a basic concept in geometry that forms the foundation for advanced geometry learning.
Dhindha Kusuma Habsyari, Puguh Darmawan
doaj   +1 more source

L’enjeu triangulaire de la trame romanesque du Roman d’Enéas [PDF]

Çédille: Revista de Estudios Franceses, 2013
The heroic path of Aeneas is generally defined by three linear events: his stay in Carthage, his descent into Hell, and the founding of future Rome.
Catherine Desprès Caubrière
doaj  

The geopolitical triangle of the USA, Japan, and the Republic of Korea in the context of the transformation of the Asia-Pacific region's security structure [PDF]

Известия Саратовского университета. Новая серия: Cоциология. Политология
This article analyzes the evolution of the US – Japan – Republic of Korea geopolitical triangle amid the transformation of the Asia-Pacifi c region’s security architecture.
Naumenko, Alina S., Saltanov, Stanislav D.   +1 more
doaj   +1 more source

Troponin T and Neurofilament Light Chain Levels as Complementary Biomarkers of Disease Accumulation and Aggressiveness in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a clinically heterogeneous neurodegenerative disease requiring reliable biomarkers to improve patient stratification and trial design. While serum neurofilament light chain (sNfL) reflects neuroaxonal stress and disease aggressiveness, troponin T (TnT) may capture complementary aspects of ...
Julia Sellin, Sofia Waldorf, Janina von der Gablentz, Torsten Grehl, Huelya Nazlican, Thomas Meyer, Julian Grosskreutz, Patrick Weydt, Sarah Bernsen   +8 more
wiley   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

Efficient Algorithms for Subgraph Listing

Algorithms, 2014
Subgraph isomorphism is a fundamental problem in graph theory. In this paper we focus on listing subgraphs isomorphic to a given pattern graph. First, we look at the algorithm due to Chiba and Nishizeki for listing complete subgraphs of fixed size, and ...
Niklas Zechner, Andrzej Lingas
doaj   +1 more source