Results 121 to 130 of about 31,680 (296)
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
Advanced Science, EarlyView.This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
Advanced Science, EarlyView.A nano‐plasma device enables watt‐level on‐chip THz generation through picosecond switching triggered by secondary electron emission avalanche. An ultra‐dense electron sheet initiates nano‐plasma formation within a ∼100 nm gap, driving rapid energy release into an integrated resonator.
Guangyu Sun +4 more
wiley +1 more source
Modeling Pedestrian Dynamics on Triangular Grids
, 2014 We study the modeling of pedestrian dynamics on triangular grids. We consider the cases both with and without orientation. The geometry of a path with orientation may be represented by a special triangular grid with a continuously reducing number of grid
Bärwolff, Günter +2 more
core +1 more source
Advanced Science, EarlyView.TarPass provides a rigorous benchmark for target‐aware de novo molecular generation by jointly evaluating protein‐ligand interactions, molecular plausibility, and drug‐likeness on 18 well‐studied targets. Results show that current models often fail to consistently surpass random baseline in target‐specific enrichment, while post hoc multi‐tier virtual ...
Rui Qin +11 more
wiley +1 more source
Advanced Science, EarlyView.Defect‐configurational origins of the asymmetric apparent electrostrain are revealed in different piezoelectric ceramics via atomic‐scale visualization of defect configurations. Migration of oxygen vacancies leads to the electrobending effect in N2‐sintered BaTiO3, while defect dipoles in Ba0.99TiO2.99 generate true asymmetric electrostrain without ...
Jie Wang +7 more
wiley +1 more source
Free-form, form finding and anisotropic grid shell
, 2010 p. 966-876The new geometrical developments open new perspectives for free-form design, making it possible to escape from planar triangular or quadrilateral discretizations.
RAYNAUD, J., BALDASSINI, N.
core
Imaging Electric Polarization Switching in Multilayer Graphene
Advanced Science, EarlyView.Domain wall sliding‐induced electric polarization switching is directly observed for the first time in multilayer graphene, enabled by a novel optical readout method. The polarization switching is realized upon application of global and local electric fields, and mechanical forces between neighboring polar domains of opposite out‐of‐plane polarizations
Zhou Zhou +10 more
wiley +1 more source
Optimal error-detecting open-locating-dominating set on the infinite triangular grid
Discussiones Mathematicae Graph Theory, 2023 Devin Jean, Suk J. Seo
doaj +1 more source
Grid Optimization of Free-Form Spatial Structures Considering the Mechanical Properties
BuildingsIn recent years, the application of free-form surface spatial grid structures in large public buildings has become increasingly common. The layouts of grids are important factors that affect both the mechanical performance and aesthetic appeal of such ...
Fengcheng Liu +3 more
doaj +1 more source