Results 31 to 40 of about 30,894 (155)

Physical-chemical properties of 5-(3-fluorophenyl)-4-amino-1,2,4-triazole-3-thiol s-derivatives

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
Introduction. Currently an attempt to combine 1,2,4-triazole heterocycle with various pharmacologically active fragments of other organic molecules is popular among the scientists.
O. A. Bihdan, V. V. Parchenko
doaj   +1 more source

Di- and Tri-nuclear VIII and CrIII Complexes of Dipyridyltriazoles: Ligand Rearrangements, Mixed Valency and Ferromagnetic Coupling

Frontiers in Chemistry, 2020
The first dinuclear and trinuclear chromium(III) and dinuclear vanadium(III) complexes of N4-R-substituted-3,5-di(2-pyridyl)-1,2,4-triazole (Rdpt) ligands have been prepared by solvothermal complexations under inert atmospheres, and characterized.
Julia Rinck, Julia Rinck, Jonathan A. Kitchen, Jonathan A. Kitchen, Anthony B. Carter, Yanhua Lan, Christopher E. Anson, Karin Fink, Sally Brooker, Annie K. Powell, Annie K. Powell   +10 more
doaj   +1 more source

Metal Free Domino β‑Azidation/[3 + 2] Cycloaddition Reaction for the Synthesis of 1,2,3-Triazole-Fused Dihydrobenzoxazinones

, 2019
A metal free DBU catalyzed synthesis of 1,2,3-triazole-fused dihydrobenzoxazinone derivatives by tandem β-azidation/[3 + 2] cycloaddition reaction has been developed under mild conditions.
Kiranmai Nayani (7148414), Sangeetha Donikela (1589692), Prathama S. Mainkar (447913), Srivari Chandrasekhar (626160)   +3 more
core   +2 more sources

Click Triazoles for Bioconjugation [PDF]

, 2012
Click Chemistry is a set of rapid, selective and robust reactions that give near-quantitative yield of the desired product in aqueous solutions. The Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that forms 1,4-disubstituted triazoles is a prototypical example of click chemistry that features exquisite selectivity and bioorthogonality-that is, non ...
Tianqing, Zheng, Sara H, Rouhanifard, Abubakar S, Jalloh, Peng, Wu   +3 more
openaire   +2 more sources

Long-term effect of antifungal therapy for the treatment of severe resistant asthma: an active comparator clinical trial [PDF]

Current Medical Mycology, 2019
Background and Purpose: Itraconazole therapy has been reported to control asthma in severe therapy-resistant asthma with fungal sensitization. The aim of this study was to investigate the impact of anti-fungal therapy on the treatment of severe asthma ...
Majid Mirsadraee, Sanaz Dehghan, Shadi Ghaffari, Niloofar Mirsadraee   +3 more
doaj   +1 more source

N-[(E)-Quinolin-2-ylmethylidene]-1,2,4-triazol-4-amine hemihydrate

IUCrData, 2020
The title hemihydrate, C12H9N5·0.5H2O, was isolated from the condensation reaction of quinoline-2-carbaldehyde with 4-amino-4H-1,2,4-triazole. The Schiff base molecule adopts an E configuration about the C=N bond and is approximately planar, with a ...
Nurulizzatul Ningsheh M. Shahri, Nur Halilatul Sadiqin Omar Ali, Malai Haniti Sheikh Abdul Hamid, Aminul Huq Mirza, Anwar Usman, Md Rejaul Hoq, Mohammad R. Karim   +6 more
doaj   +1 more source

Synthesis and biological evaluation of selective phosphonate-bearing 1,2,3-triazole-linked sialyltransferase inhibitors

, 2021
The critical role of sialyltransferase (ST) enzymes in tumour cell growth and metastasis, as well as links to multi-drug and radiation resistance, has seen STs emerge as a target for potential antimetastatic cancer treatments.
Andrew P Montgomery (20254962), Haibo Yu (273911), Danielle Skropeta (2662507), Christopher Dobie (17754743), Rémi Szabo (20165334)   +4 more
core   +1 more source

Design, Synthesis and Bioevaluation of Highly Functionalized 1,2,3-Triazole-Guanidine Conjugates as Anti-Inflammatory and Antioxidant Agents

, 2022
In search of new biologically potent molecules a small focused library of new guanidine-1,2,3-triazole hybrid derivatives were synthesized via Organocatalytic enolate- mediated azide-carbonyl [3 + 2] cycloaddition yielding a highly functionalized ...
Mubarak H. Shaikh (9373121), Vijay M. Khedkar (554344), Ashish Asrondkar (13213621), Amit A. Pund (9366913), Rashiqua A. Siddiqui (13213618), Bapurao B. Shingate (8051171), Prathmesh P. Deshpande (13213624), Amol A. Nagargoje (9383810), Madiha A. Siddiqui (13213615)   +8 more
core   +1 more source

Density Function Theory Study on the Energy and Circular Dichroism Spectrum for Methylene-Linked Triazole Diads Depending on the Substitution Position and Conformation

Molecules
Since the discovery of metal-catalyzed azide–alkyne cycloadditions, 1,2,3-triazoles have been widely used as linkers for various residues. 1,2,3-Triazole is an aromatic five-membered cyclic compound consisting of three nitrogen and two carbon atoms with ...
Masaki Nakahata, Akihito Hashidzume
doaj   +1 more source

Synthesis and Characterization of Carbazole-Benzothiadiazole-Based Conjugated Polymers for Organic Photovoltaic Cells with Triazole in the Main Chain

International Journal of Photoenergy, 2013
We have synthesized a series of carbazole-benzothiadiazole-triazole based copolymers, poly[(N-9′-heptadecanyl-2,7-carbazole)-co-(5,5-(4′,7′-di-2-thienyl-2′,1′,3′-benzothiadiazole))-co-((4-(4-butylphenyl)-3,5-diphenyl-4H-1,2,4]triazole))] (PCz3TBTz) by ...
Eunhee Lim
doaj   +1 more source