The synthesis of [1,2,3]-triazole-based bent core liquid crystals via microwave-mediated ‘Click Reaction’ and their mesomorphic behaviour [PDF]
, 2019 A series of [1,2,3]-triazole-based liquid crystal compounds were synthesised via a fast and efficient microwave-mediated ‘Click Reaction’ and their phase behaviour is presented.
Samuel Sprunt (2529220) +2 more
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1,2,4-Triazole-3,5-diylidene: A Building Block for Organometallic Polymer Synthesis [PDF]
, 2016 1,2,4-Triazole-3,5-diylidene: A Building Block for Organometallic Polymer ...
Olivier Guerret (2728345) +5 more
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Long-term effect of antifungal therapy for the treatment of severe resistant asthma: an active comparator clinical trial [PDF]
Current Medical Mycology, 2019 Background and Purpose: Itraconazole therapy has been reported to control asthma in severe therapy-resistant asthma with fungal sensitization. The aim of this study was to investigate the impact of anti-fungal therapy on the treatment of severe asthma ...
Majid Mirsadraee +3 more
doaj +1 more source
Click Triazoles for Bioconjugation [PDF]
, 2012 Click Chemistry is a set of rapid, selective and robust reactions that give near-quantitative yield of the desired product in aqueous solutions. The Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that forms 1,4-disubstituted triazoles is a prototypical example of click chemistry that features exquisite selectivity and bioorthogonality-that is, non ...
Tianqing, Zheng +3 more
openaire +2 more sources
Recent Developments Towards the Synthesis of Triazole Derivatives: A Review
OrganicsThe triazole scaffold is a crucial component of heterocyclic chemistry, serving as a basic building block in organic synthesis, materials science, and medicinal chemistry.
Issam Ameziane El Hassani +4 more
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N-[(E)-Quinolin-2-ylmethylidene]-1,2,4-triazol-4-amine hemihydrate
IUCrData, 2020 The title hemihydrate, C12H9N5·0.5H2O, was isolated from the condensation reaction of quinoline-2-carbaldehyde with 4-amino-4H-1,2,4-triazole. The Schiff base molecule adopts an E configuration about the C=N bond and is approximately planar, with a ...
Nurulizzatul Ningsheh M. Shahri +6 more
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Synthesis and biological evaluation of selective phosphonate-bearing 1,2,3-triazole-linked sialyltransferase inhibitors [PDF]
, 2021 The critical role of sialyltransferase (ST) enzymes in tumour cell growth and metastasis, as well as links to multi-drug and radiation resistance, has seen STs emerge as a target for potential antimetastatic cancer treatments.
Andrew P Montgomery (20254962) +4 more
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Design and Synthesis of Novel 3‑Nitro‑1H‑1,2,4-triazole-1,2,3-triazole-1,4-disubstituted Analogs as Promising Antitrypanosomatid Agents: Evaluation of In Vitro Activity against Chagas Disease and Leishmaniasis [PDF]
A series of 28 compounds, 3-nitro-1H-1,2,4-triazole, were synthesized by click-chemistry with diverse substitution patterns using medicinal chemistry approaches, such as bioisosterism, Craig-plot, and the Topliss set with excellent yields.
Carla C. P. Arruda (15367833) +20 more
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Regioselective synthesis, antitumor and antioxidant activities of some 1,2,4-triazole derivatives based on 4-phenyl-5-(quinolin-8-yloxy)methyl-4H-1,2,4-triazole-3-thiol [PDF]
, 2017 Regioselective synthesis of some triazole derivatives 4–18 was achieved from the versatile, readily accessible 4-phenyl-5-(quinolin-8-yloxy)methyl-4H-1,2,4-triazole-3-thiol/thione 3.
M. S. Amine (3610862) +2 more
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International Journal of Photoenergy, 2013 We have synthesized a series of carbazole-benzothiadiazole-triazole based copolymers, poly[(N-9′-heptadecanyl-2,7-carbazole)-co-(5,5-(4′,7′-di-2-thienyl-2′,1′,3′-benzothiadiazole))-co-((4-(4-butylphenyl)-3,5-diphenyl-4H-1,2,4]triazole))] (PCz3TBTz) by ...
Eunhee Lim
doaj +1 more source