Results 61 to 70 of about 14,054 (220)

Piperazine Derivatives: A Privileged Scaffold in Modern Synthesis and Medicinal Chemistry

ChemistryOpen, Volume 15, Issue 1, January 2026.
Piperazine‐based bioactive molecules represent a versatile class of compounds with broad therapeutic potential. Structural modification of the piperazine scaffold governs key structure–activity relationships, enabling antibacterial, antifungal, antitumor, neuroactive, and anti‐inflammatory activities.
Assel Ten, Raushan Koizhaiganova, Dilnaz Bissenbay, Bagila Tursynova, Zhanar Zhaxibayeva, Valentina Yu   +5 more
wiley   +1 more source

Advances in Microbial Diagnostics: Machine Learning and Nanotechnology for Zoonotic Disease Control

WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 1, January/February 2026.
This review highlights how integrating machine learning with nanotechnology enables enhanced diagnostics, personalized treatments, and the prediction of outbreaks for zoonotic diseases, offering a unified framework to advance global health. ABSTRACT Zoonotic diseases pose significant global health threats, with microbial pathogens, including bacteria ...
Narges Lotfalizadeh, Cinzia Santucciu, Valentina Chisu, Helia Sepahvand, Abbas Rahdar, Razieh Behzadmehr, Octavio Luiz Franco, Guettari Moez, Luiz Fernando Romanholo Ferreira   +8 more
wiley   +1 more source

Assessment of Trichinella Infection in Animals from Argentina

Parasitologia
Parasites of the genus Trichinella are widely distributed and infect a wide range of domestic and wild animals. Their presence spans across various continents, impacting agricultural and wildlife ecosystems alike.
Fernando A. Fariña, Mariana I. Pasqualetti, Marina Winter, Sergio Abate, Gustavo Daneri, Ana Harrington, Tatiana Aronowicz, Claudio Calvo, Cecilia Lapuyade, Florencia A. D’Francisco, M. Mabel Ribicich   +10 more
doaj   +1 more source

Biomolecular changes and cortical neurodegenerative lesions in Trichinella spiralis infected BALB/c mice: a preliminary study elucidating a potential relationship between systemic helminthic infections and idiopathic Parkinson’s

Helminthologia, 2018
Idiopathic Parkinson’s (IP) is a neurodegenerative disease that is suspected to be due to exposure to infections during early life. Toxoplasmosishas been the only suspected parasitic infection in IP (Celik et al., 2010).
Saad M. Hasby, Safwat O., El-Guindy D., Raafat R., Elgendy D., Hasby E.   +5 more
doaj   +1 more source

Helminth Infections: Recognition and Modulation of the Immune Response by Innate Immune Cells [PDF]

, 2018
The survival of helminths in the host over long periods of time is the result of a process of adaptation or dynamic co-evolution between the host and the parasite. However, infection with helminth parasites causes damage to the host tissues producing the
Ambrosio, Laura Fernanda, Celias, Daiana Pamela, Cervi, Laura Alejandra, Chiapello, Laura Silvina, Motran, Claudia Cristina, Silvane, Leonardo Micael, Theumer, Martín Gustavo, Volpini, Ximena   +7 more
core   +1 more source

Polyparasitism and Anaemia Among Women of Reproductive Age in Kilifi County—Kenya

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Background Polyparasitism is commonly associated with Plasmodium species, Schistosoma species and soil‐transmitted helminths. Anaemia results from a variety of causes, including parasitic infections. Women of reproductive age (WRA) and children below the age of five are disproportionately affected by polyparasitic infections, putting them at risk of ...
Matano Mjomba, Simon Muriu, Victor Tunje Jeza, Pedro P. Chieffi   +3 more
wiley   +1 more source

Efficacy of flubendazole and albendazole against Trichinella spiralis in mice

Parasite, 2001
Efficacy of flubendazole and albendazole against Trichinella spiralis in mice were studied. ICR mice were experimentally infected with Trichinella spiralis and treated with either flubendazole (FBZ) or albendazole (ABZ) at four different stages of the ...
Chung M.S., Joo K.H., Quan F.S., Kwon H.S., Cho S.W.   +4 more
doaj   +1 more source

Fasciola hepatica‐Derived Proteins Shield the Heart From Type 2 Myocardial Infarction in Rats by Modulating Oxidative Stress and Inflammatory Imbalance: Insights Relevant to the Hygiene Hypothesis

Oxidative Medicine and Cellular Longevity, Volume 2026, Issue 1, 2026.
Myocardial infarction (MI) remains a leading cause of mortality worldwide, with type 2 MI (T2MI) carrying a worse prognosis than type 1 MI (T1MI). The hygiene hypothesis suggests that reduced microbial exposure in sanitized environments contributes to immune dysregulation and inflammation‐related diseases.
Mohammadreza Ahmadi-Beni, Kobra Mokhtarian, Gholam Reza Mobini, Somayeh Najafi-Chaleshtori, Najmeh Salehi-Vanani, Maryam Anjomshoa, Fariba Houshmand, Balakrishnan Rengasamy   +7 more
wiley   +1 more source

Expressed sequence tags from life cycle stages of Trichinella spiralis: Application to biology and parasite control [PDF]

, 2005
While the approach taken to date to study Trichinella spp., involves mainly characterization of individual genes of interest, we initiated a genomics approach as an antecedent to more complete genome sequencing.
Appleton, Judith, Jasmer, Douglas P., McCarter, James P., Mitreva, Makedonka   +3 more
core  

Advice on animal and public health risks of insects reared on former foodstuffs as raw material for animal feed

Food Risk Assess Europe, Volume 4, Issue 1, January 2026.
Abstract In the coming decades, there is expected to be a sharply increased demand for dietary proteins for humans and animals. As a result, there is an increasing focus on reared insects as a new source of protein. According to the Ministry of Agriculture, Nature and Food Quality (LNV), the use of food chain residual flows such as former foodstuffs as
L.F.F. Kox, D.T.H.M. Sijm
wiley   +1 more source