Relevance of Nutrient-Sensing in the Pathogenesis of Trichophyton rubrum and Trichophyton interdigitale [PDF]
Frontiers in Fungal Biology, 2022 The growth and development of organisms depend on nutrient availability. Dermatophytes must sense nutrient levels and adapt to the host environment to colonize human and animal keratinized tissues.
Aline H. S. Cruz +9 more
doaj +3 more sources
Terbinafine Resistance in <i>Trichophyton rubrum</i> and <i>Trichophyton indotineae</i>: A Literature Review. [PDF]
Antibiotics (Basel)Background/Objectives: Terbinafine has been the gold standard for the management of superficial fungal infections. The etiological agent generally is Trichophyton rubrum (T.
Gupta AK +5 more
europepmc +2 more sources
Clinical Isolate of a Multi-Antifungal-Resistant Trichophyton rubrum. [PDF]
Antimicrob Agents Chemother, 2022 The multi-antifungal drug-resistant strain (NUBS21012) of Trichophyton rubrum was isolated from a patient with recurrent tinea corporis. The resistant strain encoded Phe at codon 393 instead of Leu (L393F) in the squalene epoxidase (SQLE) gene.
Kano R, Kimura U, Noguchi H, Hiruma M.
europepmc +2 more sources
The taxonomy of the Trichophyton rubrum complex: a phylogenomic approach. [PDF]
Microb Genom, 2021 The medically relevant Trichophyton rubrum species complex has a variety of phenotypic presentations but shows relatively little genetic differences. Conventional barcodes, such as the internal transcribed spacer (ITS) region or the beta-tubulin gene ...
Cornet L +6 more
europepmc +2 more sources
Multiple Dermal Abscesses by Trichophyton rubrum in an Immunocompromised Patient [PDF]
Frontiers in Medicine, 2019 We report the case of a 52-year-old man who presented with a 10 year history of multiple nodules with purulent drainage on the upper extremities. Several attempts of treatment with oral antibiotics had been unsuccessful.
Frédéric Toussaint +1 more
openalex +2 more sources
HacA Governs Virulence Traits and Adaptive Stress Responses in Trichophyton rubrum [PDF]
Frontiers in Microbiology, 2020 The ability of fungi to sense environmental stressors and appropriately respond is linked to secretory system functions. The dermatophyte infection process depends on an orchestrated signaling regulation that triggers the transcription of genes ...
Tamires A. Bitencourt +7 more
openalex +2 more sources
Definitions, 2020 This datasheet on Trichophyton rubrum covers Identity, Distribution.
National Cancer Institute
openalex +2 more sources
Terbinafine Resistance of Trichophyton Clinical Isolates Caused by Specific Point Mutations in the Squalene Epoxidase Gene [PDF]
Antimicrobial Agents and Chemotherapy, 2017 Terbinafine is one of the allylamine antifungal agents whose target is squalene epoxidase (SQLE). This agent has been extensively used in the therapy of dermatophyte infections.
Tsuyoshi Yamada +2 more
exaly +3 more sources
The First Isolation of Multiple Antifungal-Drug-Resistant Trichophyton Rubrum in China and the Novel Resistance Mechanism. [PDF]
MycosesABSTRACT Objectives This study reports the first isolation of a multidrug‐resistant Trichophyton rubrum strain in China, characterizing its drug resistance profile and mechanisms. Methods The isolate was identified by internal transcribed spacer (ITS) sequencing and phylogenetic analysis.
Song G +8 more
europepmc +2 more sources
Influence of the cultivation medium and pH on the pigmentation of Trichophyton rubrum.
PLoS ONE, 2019 Trichophyton rubrum is a human pathogenic fungus. As a dermatophyte it causes athlete's foot, fungal infection of nails, jock itch and ringworm. The pigmentation of T. rubrum is variable and can range from white or yellow to wine-red. We demonstrate that
Oliver Blechert +4 more
doaj +2 more sources