Relevance of Nutrient-Sensing in the Pathogenesis of Trichophyton rubrum and Trichophyton interdigitale [PDF]
Frontiers in Fungal Biology, 2022 The growth and development of organisms depend on nutrient availability. Dermatophytes must sense nutrient levels and adapt to the host environment to colonize human and animal keratinized tissues.
Aline H. S. Cruz +9 more
doaj +3 more sources
Clinical Isolate of a Multi-Antifungal-Resistant Trichophyton rubrum. [PDF]
Antimicrob Agents Chemother, 2022 The multi-antifungal drug-resistant strain (NUBS21012) of Trichophyton rubrum was isolated from a patient with recurrent tinea corporis. The resistant strain encoded Phe at codon 393 instead of Leu (L393F) in the squalene epoxidase (SQLE) gene.
Kano R, Kimura U, Noguchi H, Hiruma M.
europepmc +2 more sources
The taxonomy of the Trichophyton rubrum complex: a phylogenomic approach. [PDF]
Microb Genom, 2021 The medically relevant Trichophyton rubrum species complex has a variety of phenotypic presentations but shows relatively little genetic differences. Conventional barcodes, such as the internal transcribed spacer (ITS) region or the beta-tubulin gene ...
Cornet L +6 more
europepmc +2 more sources
Terbinafine Resistance of Trichophyton Clinical Isolates Caused by Specific Point Mutations in the Squalene Epoxidase Gene [PDF]
Antimicrobial Agents and Chemotherapy, 2017 Terbinafine is one of the allylamine antifungal agents whose target is squalene epoxidase (SQLE). This agent has been extensively used in the therapy of dermatophyte infections.
Tsuyoshi Yamada +2 more
exaly +3 more sources
Jurnal Kesehatan Andalas, 2019 Dermatofitosis adalah penyakit akibat kolonisasi jamur dermatofit dengan agen penyebab terbanyak yaitu jamur Trichophyton rubrum. Daun kesum (Polygonum minus Huds.) mengandung senyawa-senyawa metabolit sekunder yang dapat digunakan sebagai antijamur ...
Shintya Dewi +3 more
doaj +2 more sources
Influence of the cultivation medium and pH on the pigmentation of Trichophyton rubrum.
PLoS ONE, 2019 Trichophyton rubrum is a human pathogenic fungus. As a dermatophyte it causes athlete's foot, fungal infection of nails, jock itch and ringworm. The pigmentation of T. rubrum is variable and can range from white or yellow to wine-red. We demonstrate that
Oliver Blechert +4 more
doaj +2 more sources
Trichophyton rubrum Azole Resistance Mediated by a New ABC Transporter, TruMDR3
Antimicrobial Agents and Chemotherapy, 2019 The mechanisms of terbinafine resistance in a set of clinical isolates of Trichophyton rubrum have been studied recently. Of these isolates, TIMM20092 also showed reduced sensitivity to azoles.
Michel Monod +2 more
exaly +2 more sources
Rapid and specific detection of Trichophyton rubrum and Trichophyton mentagrophytes using a loop-mediated isothermal amplification assay [PDF]
MethodsX, 2022 Trichophyton rubrum and Trichophyton mentagrophytes are the main causative pathogens of onychomycosis. However, the sensitivity and specificity of conventional microscopic tests are insufficient for reliable diagnoses of onychomycosis.
Mi-Ran Seo +4 more
doaj +2 more sources
Disparate SAR Data of Griseofulvin Analogues for the Dermatophytes Trichophyton mentagrophytes, T. rubrum, and MDA-MB-231 Cancer Cells [PDF]
, 2012 Alwin Krämer +39 more
core +3 more sources