Results 81 to 90 of about 2,460 (178)
Conservation of context-dependent splicing activity in distant Muscleblind homologs [PDF]
, 2016 The Muscleblind (MBL) protein family is a deeply conserved family of RNA binding proteins that regulate alternative splicing, alternative polyadenylation, RNA stability and RNA localization. Their inactivation due to sequestration by expanded CUG repeats
Berglund, J. Andrew +4 more
core +1 more source
Beauty in the beast – Placozoan biodiversity explored through molluscan predator genomics
Ecology and Evolution, Volume 14, Issue 4, April 2024.Previous assumptions about the primary habitat of Placozoa are challenged, and their broader diversity beyond disc‐shaped grazers in coastal waters is revealed. The discovery of placozoan‐predatory sea slugs prompts consideration of a new ecological niche: seafloor sediment interstices.
Michael Eitel +3 more
wiley +1 more source
Proteoglycans in mechanobiology of tissues and organs: Normal functions and mechanopathology
Proteoglycan Research, Volume 2, Issue 2, April-June 2024.Abstract Proteoglycans (PGs) are a diverse class of glycoconjugates that serve critical functions in normal mechanobiology and mechanopathology. Both the protein cores and attached glycosaminoglycan (GAG) chains function in mechanically sensitive processes, and loss of either can contribute to development of pathological conditions. PGs function as key
Mary C. Farach‐Carson +2 more
wiley +1 more source
Evolutionary insights into premetazoan functions of the neuronal protein homer. [PDF]
, 2014 Reconstructing the evolution and ancestral functions of synaptic proteins promises to shed light on how neurons first evolved. The postsynaptic density (PSD) protein Homer scaffolds membrane receptors and regulates Ca(2+) signaling in diverse metazoan ...
Burkhardt, Pawel +5 more
core +1 more source
Importance of fatty acid binding proteins in cellular function and organismal metabolism
Journal of Cellular and Molecular Medicine, Volume 28, Issue 5, March 2024.Abstract Fatty acid binding proteins (Fabps) are small soluble proteins that are abundant in the cytosol. These proteins are known to bind a myriad of small hydrophobic molecules and have been postulated to serve a variety of roles, yet their precise functions have remained an enigma over half a century of study.
Luis B. Agellon
wiley +1 more source
Multiple surveys employing a new sample‐processing protocol reveal the genetic diversity of placozoans in Japan [PDF]
, 2018 Placozoans, flat free‐living marine invertebrates, possess an extremely simple bauplan lacking neurons and muscle cells and represent one of the earliest‐branching metazoan phyla. They are widely distributed from temperate to tropical oceans.
Miyazawa Hideyuki +2 more
core +2 more sources
Evolution of selenoproteins in the metazoan
BMC Genomics, 2012 Background The selenocysteine (Sec) containing proteins, selenoproteins, are an important group of proteins present throughout all 3 kingdoms of life.
Jiang Liang, Ni Jiazuan, Liu Qiong
doaj +1 more source
Emergence, development and diversification of the TGF-
BMC Evolutionary Biology, 2009 Background The question of how genomic processes, such as gene duplication, give rise to co-ordinated organismal properties, such as emergence of new body plans, organs and lifestyles, is of importance in developmental and evolutionary biology.
Moustakas Aristidis +5 more
doaj +1 more source
Comparative analysis of Drosophila and mammalian complexins as fusion clamps and facilitators of neurotransmitter release [PDF]
, 2010 The SNARE-binding protein complexin (Cpx) has been demonstrated to regulate synaptic vesicle fusion. Previous studies are consistent with Cpx functioning either as a synaptic vesicle fusion clamp to prevent premature exocytosis, or as a facilitator to ...
Cho, Richard W. +2 more
core +1 more source
BMC Evolutionary Biology, 2010 Background Comparative genomics of the early diverging metazoan lineages and of their unicellular sister-groups opens new window to reconstructing the genetic changes which preceded or accompanied the evolution of multicellular body plans.
Manuel Michaël, Alié Alexandre
doaj +1 more source