Results 191 to 200 of about 9,044 (210)
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Trichodermadiene: a new trichothecene
Tetrahedron Letters, 1980A new trichothecene, trichodermadiene (3), possessing a dienic ester side chain has been isolated and characterized.
Eugene P. Mazzola +4 more
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Chromatography of Trichothecene Mycotoxins
Journal of Liquid Chromatography, 1986Abstract Trichothecene mycotoxins occur in agricultural commodities and can cause problems from feed refusal to death in animals. This paper describes chromatographic methods for selective analysis for trichothecene mycotoxins. These methods include gas chromatography (GC), thin layer chromatography (TLC), and high pressure liquid chromatography (HPLC).
W. Hyde +3 more
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2009
Publisher Summary Trichothecene mycotoxins are a family of tetracyclic sesquiterpenoid substances comprising over 200 compounds of widely varying toxicity. The epoxy group at C-12 and C-13 is considered essential for toxicity. Trichothecenes are broadly divided into two groups, the macrocyclic and nonmacrocyclic, based on the presence or absence of a ...
Val R. Beasley, Wanda M. Haschek
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Publisher Summary Trichothecene mycotoxins are a family of tetracyclic sesquiterpenoid substances comprising over 200 compounds of widely varying toxicity. The epoxy group at C-12 and C-13 is considered essential for toxicity. Trichothecenes are broadly divided into two groups, the macrocyclic and nonmacrocyclic, based on the presence or absence of a ...
Val R. Beasley, Wanda M. Haschek
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HPLC-MS-Method for A-Trichothecenes
Mycotoxin Research, 2001Gaschromatography with electron capture detection belongs to the most important methods for analysing the A-trichothecenes T-2 toxin, HT-2 toxin and diacetoxyscirpenol. The need of a derivatisation for these mycotoxins prior detection is the main disadvantage of this method.
Binder M, Thimm N, Handl J
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Journal of Veterinary Medicine Series A, 1986
SummaryT‐2 toxin, HT‐2 toxin, Diacetoxyscirpenol (DAS), Roridin A, Verrucarin A and 3‐Acetyl‐deoxynivalenol (3‐AcDON) were dissolved in dimethyl sulfoxide and applied topically to mice. For a mortality study, groups of 10–20 male mice received either 5, 10, 20, 30 or 40 mg toxin/kg BW. Further, mixtures of trichothecenes were applied, e. g.: T‐2 toxin +
H. B. Schiefer +2 more
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SummaryT‐2 toxin, HT‐2 toxin, Diacetoxyscirpenol (DAS), Roridin A, Verrucarin A and 3‐Acetyl‐deoxynivalenol (3‐AcDON) were dissolved in dimethyl sulfoxide and applied topically to mice. For a mortality study, groups of 10–20 male mice received either 5, 10, 20, 30 or 40 mg toxin/kg BW. Further, mixtures of trichothecenes were applied, e. g.: T‐2 toxin +
H. B. Schiefer +2 more
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Trichothecene Production byTrichoderma brevicompactum
Journal of Agricultural and Food Chemistry, 2005Trichoderma brevicompactum, T. viride, T. harzianum, T. atroviride, T. longibrachiatum, T. erinaceum, T. citrinoviride, and Hypocrea lutea were screened for production of trichothecenes after growth on one or several solid and liquid media. Trichothecenes were detected by liquid chromatography combined with online UV/vis spectroscopy and electrospray ...
Doustmorad Zafari +3 more
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Environmental Microbiology, 2016
SummaryFusarium sporotrichioides genes FsTri11, FsTri13, and FsTri1 encode cytochrome P450 monooxygenases (CYPs) responsible for hydroxylations at C‐15, C‐4, and C‐8 of the trichothecene skeleton, respectively. However, the corresponding genes of nivalenol (NIV)‐chemotype Fusarium graminearum remain to be functionally elucidated.
Makoto Fujimura +13 more
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SummaryFusarium sporotrichioides genes FsTri11, FsTri13, and FsTri1 encode cytochrome P450 monooxygenases (CYPs) responsible for hydroxylations at C‐15, C‐4, and C‐8 of the trichothecene skeleton, respectively. However, the corresponding genes of nivalenol (NIV)‐chemotype Fusarium graminearum remain to be functionally elucidated.
Makoto Fujimura +13 more
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State of the art of trichothecenes analysis
Toxicology Letters, 2004Methods to analyze trichothecenes should be fast, reliable and economical. The known methods can be divided into two categories: the 'instrumental methods' as gas chromatography (GC) and high performance liquid chromatography (HPLC) and the so called 'fast methods' like thin layer chromatography (TLC), enzyme-linked immunosorbant analyses (ELISA) and ...
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Novel rearrangements of macrocyclic trichothecenes
Tetrahedron Letters, 1990Abstract Myrotoxin B ( 1 ) readily undergoes electrophilic addition of water and BrOH to give myrotoxin B hydrate ( 5 ) and the bromohydrin 2 , respectively. When these hemiketals are treated with DBU in THF, they undergo novel rearrangements apparently via their open chain hydroxyketone forms. Myrotoxin B hydrate ( 5 ) gives a spirocyclic ketal 6
Ming Zeng +2 more
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1990
The trichothecene mycotoxins are a group of tetracyclic sesquiterpenoid compounds characterized by a six-membered oxygen ring, an epoxide in the 12,13 position and an olefinic bond in the 9,10 position. They are produced by a variety of fungi including Stachybotrys, Myrothecium, Trichothecium, and particularly species of the genus Fusarium ...
C. Helaszek +2 more
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The trichothecene mycotoxins are a group of tetracyclic sesquiterpenoid compounds characterized by a six-membered oxygen ring, an epoxide in the 12,13 position and an olefinic bond in the 9,10 position. They are produced by a variety of fungi including Stachybotrys, Myrothecium, Trichothecium, and particularly species of the genus Fusarium ...
C. Helaszek +2 more
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