Results 171 to 180 of about 9,820 (223)

Trichothecenes

2018
Fil: Mourelos, Cecilia Alejandra. Universidad Nacional de La Plata. Facultad de Ciencias Agrarias y Forestales. Departamento de Ciencias Biológicas. Centro de Investigaciones de Fitopatología. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas.
Malbrán, Ismael, Mourelos, Cecilia Alejandra, Girotti, Juan Roberto, Lori, Gladys   +3 more
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Metabolic pathways of trichothecenes

Drug Metabolism Reviews, 2009
Trichothecenes are a group of mycotoxins mainly produced by the fungi of Fusarium genus. Consumers are particularly concerned over the toxicity and food safety of trichothecenes and their metabolites from food-producing animals. The metabolism of T-2 toxin, deoxynivalenol (DON), nivalenol (NIV), fusarenon-X (FX), diacetoxyscirpenol (DAS), 3-acetyldeoxy-
Qinghua, Wu, Vlastimil, Dohnal, Lingli, Huang, Kamil, Kuca, Zonghui, Yuan   +4 more
openaire   +2 more sources

Targeting Trichothecene Biosynthetic Genes

2016
Biosynthesis of trichothecenes requires the involvement of at least 15 genes, most of which have been targeted for PCR. Qualitative PCRs are used to assign chemotypes to individual isolates, e.g., the capacity to produce type A and/or type B trichothecenes. Many regions in the core cluster (consisting of 12 genes) including intergenic regions have been
Wei, Songhong, van der Lee, Theo, Verstappen, Els, van Gent, Marga, Waalwijk, Cees   +4 more
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Haematotoxicity of trichothecenes

Toxicology Letters, 2004
Human toxicosis induced by consumption of foodstuffs contaminated with trichothecenes presents one common major symptom: a haematological perturbation manifesting principally as thrombocytopenia and leukopenia. The patients have rapidly progressing coagulation problems, and compromised resistance to infections.
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Prevention strategies for trichothecenes

Toxicology Letters, 2004
Contamination of cereal commodities with mycotoxins represents a significant hazard to consumer health and has thus received increasing attention from food safety authorities and legislators. For trichothecenes, and deoxynivalenol (DON) in particular, the imminent implementation of legislative limits has focused attention on ways to prevent entry of ...
David, Aldred, Naresh, Magan
openaire   +2 more sources

Biosynthesis of Trichothecenes and Apotrichothecenes

Journal of Agricultural and Food Chemistry, 1999
Fusarium culmorum produces two major trichothecenes, 3-acetyldeoxynivalenol and sambucinol, and some minor apotrichothecenes. It was desired to investigate if during their biosynthesis a C-11-keto intermediate was involved. To verify this postulate, trichodiene, a known precursor to trichothecenes, was synthesized with two deuteriums at C-11 and one at
L O, Zamir, A, Nikolakakis, F, Sauriol, O, Mamer   +3 more
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Determination of trichothecenes in cereals

Journal of Chromatography A, 1999
An effective method for the determination of seven trichothecenes-deoxynivalenol (DON), nivalenol (NIV), T-2 tetraol (T-24), fusarenon-X (FUS-X), diacetoxyscirpenol (DAS), T-2 toxin (T-2), HT-2 toxin (HT-2) in cereals is presented. Gel permeation chromatography on Bio-Beads S-X3 was used for clean-up of acetonitrile-methanol extract.
F, Kotal, K, Holadová, J, Hajslová, J, Poustka, Z, Radová   +4 more
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Trichothecenes: Structure-Toxic Activity Relationships

Current Drug Metabolism, 2013
Trichothecenes comprise a large family of structurally related toxins mainly produced by fungi belonging to the genus Fusarium. Among trichothecenes, type A and type B are of the most concern due to their broad and highly toxic nature. In order to address structure-activity relationships (SAR) of trichothecenes, relationships between structural ...
Qinghua, Wu, Vlastimil, Dohnal, Kamil, Kuca, Zonghui, Yuan   +3 more
openaire   +2 more sources

Mode of action of trichothecenes

Pure and Applied Chemistry, 1977
Abstract
openaire   +2 more sources

Chemical Synthesis of the Trichothecenes

1985
That research in the trichothecene field is an area of intense interest cannot be disputed. In the years 1982 and 1983, there were more than 500 publications dealing with this subject, including more than 30 reviews. In addition, a comprehensive monograph has recently appeared (151).
P G, McDougal, N R, Schmuff
openaire   +2 more sources