Trichuris suis and Oesophagostomum dentatum Show Different Sensitivity and Accumulation of Fenbendazole, Albendazole and Levamisole In Vitro [PDF]
PLoS Neglected Tropical Diseases, 2014 BackgroundThe single-dose benzimidazoles used against Trichuris trichiura infections in humans are not satisfactory. Likewise, the benzimidazole, fenbendazole, has varied efficacy against Trichuris suis whereas Oesophagostomum dentatum is highly ...
Tina V A Hansen +2 more
exaly +4 more sources
Safety of viable embryonated eggs of the whipworm Trichuris suis as a novel food pursuant to Regulation (EU) 2015/2283 [PDF]
EFSA Journal, 2019 Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on viable embryonated eggs of the whipworm Trichuris suis as a novel food (NF) pursuant to Regulation (EU)
Alexandre Maciuk +2 more
exaly +3 more sources
Influence of NOD2 Variants on Trichuris suis ova Treatment Outcome in Crohn’s Disease [PDF]
Frontiers in Pharmacology, 2018 A recent randomized study of whipworm Trichuris suis ova (TSO) in ileal Crohn’s disease failed to demonstrate a clinical benefit compared to placebo after 12 weeks.
Simon U Jaeger +2 more
exaly +4 more sources
Pathway of oxfendazole from the host into the worm: Trichuris suis in pigs [PDF]
International Journal for Parasitology: Drugs and Drug Resistance, 2017 It is well known that the efficacy of a single oral dose of benzimidazoles against Trichuris spp. infections in humans and animals is poor, but is currently still used in control programmes against human trichuriasis.
Tina V.A. Hansen +5 more
doaj +2 more sources
A genetic analysis of Trichuris trichiura and Trichuris suis from Ecuador [PDF]
Parasites & Vectors, 2015 Background Since the nematodes Trichuris trichiura and T. suis are morphologically indistinguishable, genetic analysis is required to assess epidemiological cross-over between people and pigs.
Hayley Meekums +9 more
doaj +2 more sources
Dietary Inulin and Trichuris suis Infection Promote Beneficial Bacteria Throughout the Porcine Gut [PDF]
Frontiers in Microbiology, 2020 The gut microbiota (GM) displays a profound ability to adapt to extrinsic factors, such as gastrointestinal pathogens and/or dietary alterations. Parasitic worms (helminths) and host-associated GM share a long co-evolutionary relationship, exerting ...
Sophie Stolzenbach +9 more
doaj +2 more sources
Bacteria-induced egg hatching differs for Trichuris muris and Trichuris suis [PDF]
Parasites & Vectors, 2015 Background Eggs of the porcine whipworm Trichuris suis are currently explored in human clinical trials as a treatment of immune-mediated diseases. In this context, only the infective, embryonated eggs, constitute the Active Pharmaceutical Ingredient (API)
Nermina Vejzagić +5 more
doaj +2 more sources
A survey of gastrointestinal helminth infestation in smallholder backyard pigs and the first molecular identification of the two zoonotic helminths Ascaris suum and Trichuris suis in Myanmar [PDF]
BMC Veterinary ResearchBackground Parasitic infestations have a substantial economic impact on pig production. This study aimed to investigate the gastrointestinal (GI) helminths in pigs and to molecularly characterise two important nematodes, Ascaris and Trichuris species ...
Saw Bawm +13 more
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Worm burden-dependent disruption of the porcine colon microbiota by Trichuris suis infection. [PDF]
PLoS ONE, 2012 Helminth infection in pigs serves as an excellent model for the study of the interaction between human malnutrition and parasitic infection and could have important implications in human health.
Sitao Wu +5 more
doaj +2 more sources
Trichuris suis ova in inflammatory bowel disease-clinical challenges and translational pathways [PDF]
Frontiers in ImmunologyThis article reviews the mechanisms and clinical trial findings of Trichuris suis ova (TSO) for inflammatory bowel disease (IBD).The results show TSO may exert potential effects on IBD via multiple pathways, yet no significant efficacy has been confirmed
Su Zhou, Jiong Tang, Yu Wang
doaj +2 more sources