Vaccination With Trichuris muris Poly-Cysteine and Histidine-Tailed Protein p43 Protects Against Chronic Infection. [PDF]
Parasite ImmunolABSTRACT Trichuris trichiura is one of the soil transmitted geohelminths which together currently affect approximately 25% of the global population resulting in considerable morbidity particularly in children and young adults. Recent estimates put infection by T. trichiura at approximately 513 million.
Bancroft AJ +8 more
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Worm burden-dependent disruption of the porcine colon microbiota by Trichuris suis infection. [PDF]
PLoS ONE, 2012 Helminth infection in pigs serves as an excellent model for the study of the interaction between human malnutrition and parasitic infection and could have important implications in human health.
Sitao Wu +5 more
doaj +2 more sources
Trichuriasis in Human Patients from Côte d’Ivoire Caused by Novel Trichuris incognita Species with Low Sensitivity to Albendazole/Ivermectin Combination Treatment [PDF]
Emerging Infectious DiseasesAlbendazole/ivermectin combination therapy is a promising alternative to benzimidazole monotherapy alone for Trichuris trichiura control. We used fecal DNA metabarcoding to genetically characterize Trichuris spp. populations in patient samples from Côte
Abhinaya Venkatesan +11 more
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Multifunctional Thioredoxin-Like Protein from the Gastrointestinal Parasitic Nematodes Strongyloides ratti and Trichuris suis Affects Mucosal Homeostasis [PDF]
Journal of Parasitology Research, 2016 The cellular redox state is important for the regulation of multiple functions and is essential for the maintenance of cellular homeostasis and antioxidant defense.
Dana Ditgen +7 more
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A Randomised, Double-blind, Placebo-controlled Trial of Trichuris suis ova in Active Crohn's Disease. [PDF]
Journal of Crohn's and Colitis, 2017 Gerhard Rogler +2 more
exaly +2 more sources
Clear genetic distinctiveness between human- and pig-derived Trichuris based on analyses of mitochondrial datasets. [PDF]
PLoS Neglected Tropical Diseases, 2012 The whipworm, Trichuris trichiura, causes trichuriasis in ∼600 million people worldwide, mainly in developing countries. Whipworms also infect other animal hosts, including pigs (T. suis), dogs (T.
Guo-Hua Liu +8 more
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The Use of MALDI-TOF MS as a Diagnostic Tool for Adult Trichuris Species
Frontiers in Veterinary Science, 2022 Trichuriasis is considered a neglected tropical disease, being the second most common helminthiasis in humans. Detection of Trichuris in routine diagnosis is usually done by microscopic detection of eggs in fecal samples.
Julia Rivero +3 more
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Genome and transcriptome of the porcine whipworm Trichuris suis. [PDF]
Nat Genet, 2014 Trichuris (whipworm) infects 1 billion people worldwide and causes a disease (trichuriasis) that results in major socioeconomic losses in both humans and pigs.
Jex AR +16 more
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Phylogenetic evidence that two distinct Trichuris genotypes infect both humans and non-human primates. [PDF]
PLoS ONE, 2012 Although there has been extensive debate about whether Trichuris suis and Trichuris trichiura are separate species, only one species of the whipworm T. trichiura has been considered to infect humans and non-human primates.
Damiana F Ravasi +3 more
doaj +1 more source
Uptake of benzimidazoles by Trichuris suis in vivo in pigs. [PDF]
Int J Parasitol Drugs Drug Resist, 2014 It is recognized that the clinical efficacy of single dose benzimidazoles (BZs) against the nematode, Trichuris suis of pigs and the closely related Trichuris trichiura in humans is only poor to moderate. Recent in vitro studies have indicated that a low
Hansen TV +4 more
europepmc +2 more sources