Development of RP-HPLC Method for Simultaneous Determination of Triclabendazole and Ivermectin in Pharmaceutical Suspension Dosage Form. [PDF]
Rahman TU +9 more
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Spontaneous rupture of a subcapsular hepatic hematoma due to fascioliasis: A rare parasitic complication managed conservatively - Case report. [PDF]
Caballero-Alvarado J +4 more
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Initial Magnetic Resonance Imaging Findings in Hepatic Fascioliasis and Serological and Radiological Response After Triclabendazole Treatment. [PDF]
Won EJ +10 more
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Characterization of the clinical features, laboratory findings, and outcomes of human fascioliasis in a global network: a retrospective mutlicenter study. [PDF]
Henao-Martínez AF +8 more
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Pancreatitis Manifestation and Mimicking Gallstone Symptoms Caused by Fasciola Hepatica: A Case Report. [PDF]
Bigdeli Shamloo Z +2 more
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Triclabendazole for the treatment of fascioliasis and paragonimiasis
Expert Opinion on Investigational Drugs, 2005Fascioliasis and paragonimiasis, which are caused by liver flukes (Fasciola) and lung flukes (Paragonimus), are emerging public health problems. Several hundred millions of people are at risk of the two diseases that cause considerable morbidity and delay socio-economic development.
Jürg Utzinger +2 more
exaly +4 more sources
The benzimidazole derivative, triclabendazole is the main drug used against Fasciola hepatica, although its precise mode of action remains to be fully determined. Previous studies have suggested that triclabendazole acts as a microtubule inhibitor in the same manner as tubulozole-C.
Mark W Robinson +2 more
exaly +4 more sources
An in vivo study in the laboratory rat model was carried out to monitor morphological changes in adult Fasciola hepatica over a 4-day period resulting from combination treatment of triclabendazole (TCBZ) and the metabolic inhibitor, ketoconazole (KTZ). Rats were infected with the TCBZ-resistant Oberon isolate of F. hepatica and divided into 3 groups at
G P Brennan, E Hoey, A Trudgett
exaly +4 more sources

