Results 21 to 30 of about 1,374 (169)

Pharmacokinetic evaluation of co- administration of Triclabendazole and Tildipirosin in goats [PDF]

open access: yesEgyptian Journal of Animal Health, 2022
The existing research aimed to explore triclabendazole effect (10 mg/kg b.wt., orally ) on disposition kinetic of tildipirosin (4 mg/kg b.wt) administered by intravenous or intramuscular routes in goats.
doaj   +1 more source

Triclabendazole Treatment Failure for Fasciola hepatica Infection among Preschool and School-Age Children, Cusco, Peru

open access: yesEmerging Infectious Diseases, 2021
We conducted a retrospective cohort study of children who had chronic fascioliasis in the highlands of Peru to determine triclabendazole treatment efficacy. Children passing Fasciola eggs in stool were offered directly observed triclabendazole treatment (
Maria L. Morales   +5 more
doaj   +1 more source

Hepatic Fascioliasis Mimicking Hydatid Cyst and Complicated by Portal Vein Thrombosis: A Case Report From Ethiopia. [PDF]

open access: yesClin Case Rep
Contrast‐enhanced coronal CT image of the abdomen demonstrating hepatic fascioliasis, with multiple confluent hypoattenuating lesions in the liver parenchyma (blue arrowhead) and associated segmental thrombosis of the anterior branch of the right portal vein (orange arrow).
Habte BM   +5 more
europepmc   +2 more sources

RESISTANCE OF Fasciola hepatica TO TRICLABENDAZOLE, CLOSANTEL, AND RAFOXANIDE IN A SHEEP FARM IN SHARAZOR DISTRICT, KURDISTAN-IRAQ [PDF]

open access: yesBasrah Journal of Veterinary Research, 1970
Fasciolosis caused by Fasciola hepaticahas long been one of the most importanthelminthic infections of livestock in Iraq. The control of this parasite is based on the use ofanthelmintic agents, mainly triclabendazole and closantel. Sheep on a farm in Tut
Fattah Marif Hardi   +3 more
doaj   +1 more source

Efficacy of flukicides against Fasciola hepatica and first report of triclabendazole resistance on German sheep farms

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2023
Fasciola hepatica infections lead to severe health problems and production losses in sheep farming, if not treated effectively. Triclabendazole has been used extensively over decades due to its unique efficacy range against all definitive hostfluke ...
Alexandra Kahl   +9 more
doaj   +1 more source

Effects of triclabendazole and its metabolite exposure on the heart‐rate–corrected QT intervals: A randomized, placebo‐ and positive‐controlled thorough QT study in healthy individuals

open access: yesClinical and Translational Science, 2023
Triclabendazole is an effective and well‐tolerated treatment for human fascioliasis. A placebo‐ and positive‐controlled, four‐sequence by four‐period crossover study was conducted in 45 healthy participants to assess the effect of therapeutic (10 mg/kg ...
William T. Prince   +7 more
doaj   +1 more source

Study of triclabendazole effects on Fasciola hepatica’s life-supporting organs, spines and suckers responsible for stable position of the parasite in the host

open access: yesРоссийский паразитологический журнал, 2021
The purpose of the research is to study triclabendazole effects on the Fasciola’s life-supporting organs, spines and suckers which are responsible for stable position of the parasite in the host.Materials and methods.
O. I. Bibik, I. A. Arkhipov
doaj   +1 more source

A Solid-Solid Phase Transformation of Triclabendazole at High Pressures

open access: yesCrystals, 2022
Triclabendazole is an effective medication to treat fascioliasis and paragonimiasis parasitic infections. We implemented a reliable quantum mechanical method which is density functional theory at the level of ωB97XD/6-31G* along with embedded fragments ...
Imran Ali   +5 more
doaj   +1 more source

EFFECT OF ANTIHELMINS OF THE BENZIMIDAZOLE GROUP ON GLYCOGEN CONTENT IN PREIMAGINAL FASCIOLA HEPATICA

open access: yesВетеринарная патология, 2020
In this work, the effect of albendazole and two drugs containing triclabendazole, but characterized by different indices of solubility and bioavailability, on the glycogen content in preimaginal trematodes Fasciola hepatica is considered.
E. A. Sidor   +3 more
doaj   +1 more source

Single Amino Acid Polymorphisms in the Fasciola hepatica Carboxylesterase Type B Gene and Their Potential Role in Anthelmintic Resistance

open access: yesPathogens, 2023
The expression of the Fasciola hepatica carboxylesterase type B (CestB) gene is known to be induced upon exposure to the anthelmintic triclabendazole (TCBZ), leading to a substantial rise in enzyme-specific activity.
Estefan Miranda-Miranda   +3 more
doaj   +1 more source

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