Results 1 to 10 of about 114,615 (322)
Asymmetric total synthesis of tricyclic prostaglandin D2 metabolite methyl ester via oxidative radical cyclization [PDF]
Beilstein Journal of Organic ChemistryProstaglandin D2 (PGD2) is a key pathophysiological mediator in many human diseases and biological pathways. Tricyclic prostaglandin D2 metabolite methyl ester (tricyclic-PGDM methyl ester), the major urinary metabolite of PGD2, can be used as a clinical
Miao Xiao +4 more
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Concise synthesis of chiral tricyclic γ-lactams via synergistic isothiourea/Ir catalyzed asymmetric [3 + 2] annulation [PDF]
Nature CommunicationsAccessing trans-fused N-fused tricyclic frameworks with multiple contiguous stereocenters remains a major challenge in synthesis. We report a synergistic isothiourea/Ir-catalyzed [3 + 2] annulation of arylacetic acid esters with azabenzonorbornadienes ...
Guorong Xiao +2 more
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Survival after multiple in-hospital cardiac arrests due to severe amitriptyline poisoning– a case report [PDF]
International Journal of Emergency MedicineBackground Amitriptyline, a classic tricyclic antidepressant, can produce toxic effects ranging from mild antimuscarinic symptoms to severe cardiotoxicity due to sodium channel blockade. In severe cases, toxicity may rapidly progress to cardiac arrest if
Amanuel Dagabas Wakoya +8 more
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The Brugada Type 1 Electrocardiogram and Ventricular Tachycardia With High-Dose Amitriptyline
JACC: Case Reports, 2021 A 32-year-old woman with anorexia nervosa experienced ventricular tachycardia while on therapeutic-dose amitriptyline despite normal blood tests, imaging, and intracardiac recordings.
Ji-Jian Chow, MRCP +2 more
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EXTREMAL IOTA ENERGY OF A SUBCLASS OF TRICYCLIC DIGRAPHS AND SIDIGRAPHS [PDF]
Matrix Science Mathematic, 2018 The iota energy of an n-vertex digraph D is defined by Ec (𝐷) = ∑ 1 |Im(𝑧 k)|, where z1, . . ., zn are eigenvalues of D and Im(zk) is the imaginary part of eigenvalue zk . The iota energy of an n-vertex sidigraph can be defined analogously.
Fareeha Jamal, Mehtab Khan
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Energetic Materials Frontiers, 2023 A simple, mild and efficient method was proposed to construct fused tricyclic skeletons based on Mannich reaction. This work not only develops a new method to construct the tricyclic skeletons effectively, but also provides a new insight into the fused ...
Jun-hao Shi +6 more
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Fixed Points Results for Various Types of Tricyclic Contractions
Axioms, 2021 In this paper, we introduce four new types of contractions called in this order Kanan-S-type tricyclic contraction, Chattergea-S-type tricyclic contraction, Riech-S-type tricyclic contraction, Cirić-S-type tricyclic contraction, and we prove the ...
Mustapha Sabiri +3 more
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Iraqi Geological Journal, 2021 Eight cuttings samples were obtained from Sargelu and Kurrachine formations in different wells at different depths to detect steranes and triterpanes biomarkers as an indicator of the depositional environments and thermal maturity of organic matter. This
Al-Dolaimy, Arwa
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Click-Free Synthesis of a Multivalent Tricyclic Peptide as a Molecular Transporter
Pharmaceutics, 2020 The cellular delivery of cell-impermeable and water-insoluble molecules remains an ongoing challenge to overcome. Previously, we reported amphipathic cyclic peptides c[WR]4 and c[WR]5 consisting of alternate arginine and tryptophan residues as nuclear ...
Sumit Kumar +5 more
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Fused Tricyclic Guanidine Alkaloids: Insights into Their Structure, Synthesis and Bioactivity
Marine Drugs, 2022 A marine natural product possesses a diverse and unique scaffold that contributes to a vast array of bioactivities. Tricyclic guanidine alkaloids are a type of scaffold found only in marine natural products.
Nur Zahirah Abd Rani +4 more
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