Two-step synthesis of chiral fused tricyclic scaffolds from phenols via desymmetrization on nickel
Nature Communications, 2017 Tricyclic furanic compounds with multiple chiral centers are found in a variety of natural products. Here, the authors show a highly enantioselective nickel-catalyzed procedure to access tricyclic oxygen-containing scaffolds with five contiguous chiral ...
Ravindra Kumar +4 more
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Synthesis and Thermal Behavior of a Fused, Tricyclic 1,2,3,4‐Tetrazine Ring System
Angewandte Chemie - International Edition, 2015 This study presents the synthesis and characterization of a fused, tricyclic 1,2,3,4-tetrazine ring system. The molecule is synthesized in a three-step process from 5,5'-dinitro-bis,1,2,4-triazole via a di-N-amino compound.
D. Chavez +3 more
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Allosteric modulation and direct activation of glycine receptors by a tricyclic sulfonamide [PDF]
Scientific ReportsIonotropic glycine receptors (GlyRs) are chloride-permeable ligand-gated ion channels expressed in the nervous system. Alterations to glycinergic inhibition and the generation of dysfunctional GlyRs have been linked to chronic pain, a widely prevalent ...
César O. Lara +17 more
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Synthesis of Tricyclic and Tetracyclic Lactone Derivatives of Thieno[2,3-b]pyrazine or Thieno[2,3-b]quinoline: Preliminary Antitumor and Antiparasitic Activity Evaluation [PDF]
MoleculesTricyclic and tetracyclic lactone derivatives of thieno[2,3-b]pyrazine or thieno[2,3-b]quinoline, and 2H-pyrones were prepared using different methodologies.
Maria F. Martins +6 more
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Highly efficient construction of angular polycycles [PDF]
Nature CommunicationsAngular tricyclic and polycyclic skeletons feature typical cores in an intriguing type of natural products. We herein report the Lewis acids-catalyzed dearomative (3 + 2) cycloadditions of donor-acceptor cyclopropanes with benzene ring, by which ...
Yi Sun +3 more
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Geochemical application of tricyclic and tetracyclic terpanes biomarkers in crude oils of NW China
Marine and Petroleum Geology, 2015 Manfredi Rizzo
exaly +2 more sources
Nature Chemistry, 2021 The intracellular environment hosts a large number of cancer- and other disease-relevant human proteins. Targeting these with internalized antibodies would allow therapeutic modulation of hitherto undruggable pathways, such as those mediated by protein ...
O. Tietz +4 more
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EXTREMAL IOTA ENERGY OF A SUBCLASS OF TRICYCLIC DIGRAPHS AND SIDIGRAPHS [PDF]
Matrix Science Mathematic, 2018 The iota energy of an n-vertex digraph D is defined by Ec (𝐷) = ∑ 1 |Im(𝑧 k)|, where z1, . . ., zn are eigenvalues of D and Im(zk) is the imaginary part of eigenvalue zk . The iota energy of an n-vertex sidigraph can be defined analogously.
Fareeha Jamal, Mehtab Khan
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Fixed Points Results for Various Types of Tricyclic Contractions
Axioms, 2021 In this paper, we introduce four new types of contractions called in this order Kanan-S-type tricyclic contraction, Chattergea-S-type tricyclic contraction, Riech-S-type tricyclic contraction, Cirić-S-type tricyclic contraction, and we prove the ...
Mustapha Sabiri +3 more
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Iraqi Geological Journal, 2021 Eight cuttings samples were obtained from Sargelu and Kurrachine formations in different wells at different depths to detect steranes and triterpanes biomarkers as an indicator of the depositional environments and thermal maturity of organic matter. This
Al-Dolaimy, Arwa
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