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Tricyclic antidepressants for preventing migraine in adults. [PDF]

Medicine (Baltimore), 2017
Xu XM, Liu Y, Dong MX, Zou DZ, Wei YD.
europepmc   +1 more source

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Tricyclic antidepressant overdose

Jacep, 1979
First introduced in the early 1960s, tricyclic antidepressants (TCAs) have been seen increasingly in overdoses, accounting for 10% to 20% of all cases. 1-5 This is not surprising, for amitriptyline was the 29th most frequently prescribed drug in the United States in 1974.
exaly   +3 more sources

Radioimmunoassay for tricyclic antidepressants

Scandinavian Journal of Clinical and Laboratory Investigation, 1980
A sensitive radioimmunoassay for the determination of tricyclic antidepressants is described. The antibodies were produced in rabbits immunized with a conjugate of N-succinyl-nortriptyline and human serum albumin and they were shown to be specific for the tricyclic antidepressant group of drugs.
Raimo Virtanen
exaly   +3 more sources

Tricyclic Antidepressant Overdose

Pediatric Clinics of North America, 1986
Overdose of a tricyclic antidepressant is a serious and all-too-frequent occurrence. The diagnosis must be considered in known or suspected overdoses, and signs such as a dry axilla, tachycardia, and wide QRS must be specifically sought. Management depends upon support of vital functions and a thorough understanding of the pharmacology of the drug ...
N J, Braden, J E, Jackson, P D, Walson
openaire   +2 more sources

Tricyclic antidepressant poisoning

Medical Journal of Australia, 1991
To review poisoning with tricyclic antidepressants.English language literature search using Australian Medlars Service (1977-1989), manual search of journals and review of bibliographies in identified articles.Approximately 250 articles, abstracts and book chapters were selected for analysis.The literature was reviewed and 93 articles were selected as ...
L J, Dziukas, J, Vohra
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Lithium and Tricyclic Antidepressants

Psychiatric Clinics of North America, 1992
Pharmacokinetic studies of lithium and tricyclic antidepressants (TCAs) in children and adolescents report similarities to adults with respect to a wide interindividual genetic variation in the rate of elimination and with regard to the linear nature of the system.
H H, Fetner, B, Geller
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Tricyclic antidepressants and delirium

Journal of Clinical Psychopharmacology, 1983
Some patients who take tricyclic antidepressants (TCAs) develop delirium. Charts were reviewed of 125 inpatients whose TCA plasma levels had been assayed. Delirium was documented in 10 cases. The occurrence of delirium was statistically related to age, race, and loge plasma TCA levels.
R L, Livingston, D K, Zucker, K, Isenberg, R D, Wetzel   +3 more
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Tricyclic Antidepressant Agranulocytosis

The Canadian Journal of Psychiatry, 1986
Severe neutropenia is an unusual complication of antidepressant therapy. We report a case of agranulocytosis due to clomipramine, and discuss principles of management.
D S, Gravenor, J R, Leclerc, G, Blake
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Metabolism of Tricyclic Antidepressants

Cellular and Molecular Neurobiology, 1999
1. Despite the considerable advances in the treatments available for mood disorders over the past generation, tricyclic antidepressants (TCAs) remain an important option for the pharmacotherapy of depression. 2. The pharmacokinetics of TCAs are characterized by substantial presystemic first-pass metabolism, a large volume of distribution, extensive ...
M V, Rudorfer, W Z, Potter
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