Results 201 to 210 of about 85,814 (252)
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Monitoring Tricyclic Antidepressants
Therapeutic Drug Monitoring, 1980As a result of their slow onset of action, the difficulty of assessing dose-effect, and the marked interindividual variability of steady-state plasma concentration, tricyclic antidepressants present a special challenge, as well as opportunity, for therapeutic drug monitoring. As shown particularly by the twin studies of Alexanderson, the most important
F, Sjöqvist, L, Bertilsson, M, Asberg
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Tricyclic Antidepressants and Lithium
Clinics in Laboratory Medicine, 1981Although difficulty in correlating plasma levels of tricyclic antidepressants with therapeutic outcome has been reported, therapeutic monitoring can be helpful in the management of selected depressed patients. The greater toxic potential of lithium is a pressing and clear indication for therapeutic monitoring in manic patients.
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Tricyclic Antidepressants and Children
The Nurse Practitioner, 1991Tricyclic antidepressants have been used in the treatment of certain childhood disorders for more than 20 years, and indications for their use in the pediatric population are increasing. Research supports the use of tricyclics for preadolescent children as adjunctive therapy for major depression, attention deficit hyperactivity disorder, enuresis, tic ...
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Tricyclic Antidepressant Overdose
The Journal of Emergency Medicine, 2008Q a a r. Pooja Agrawal: Today’s case is that of a 64-year-old oman who was brought in to the Emergency Department y Emergency Medical Services after an apparent suiide attempt. The patient was upset that her husband was till communicating with his ex-wife, who lived in their uilding.
Pooja, Agrawal +2 more
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Tricyclic Antidepressant Toxicity
Clinical Toxicology, 1977Tricyclic antidepressants are dibenzazepine derivatives with adrenergic, anticholinergic, and direct cardio-depressant activity. Double-blind clinical studies show TCAD to be efficacious for two-thirds of depressed patients. Cardiac toxicity is significant, especially on diseased myocardium.
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Tricyclic Antidepressant Cardiotoxicity
JAMA: The Journal of the American Medical Association, 1977To the Editor.— The article by Robinson and Barker (236:2089, 1976) regarding tricyclic antidepressant (TCA) toxicity has its good and bad features. The good is that the Food and Drug Administration and its advisors are continuing to present their data and views in a general scientific forum.
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The Efficacy of Tricyclic Antidepressants
JAMA: The Journal of the American Medical Association, 1988To the Editor. — In the July 15 issue of JAMA , Dr Renshaw 1 presents a case discussion of the use of a tricyclic antidepressant in treating a young woman with interstitial cystitis and depression. While I found the case interesting, I take issue with the assumption that the presence of anticholinergic side effects means a therapeutic blood level has ...
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The analgesic effect of tricyclic antidepressants
Brain Research, 1990The analgesia produced by tricyclic antidepressants (TCAs) in rats and the role of serotonin in this analgesia have been investigated in this study. Rats received intraperitoneal injections of imipramine and amitriptyline, which are TCAs, and the serotonin synthesis inhibitor, pCPA.
TURA, B, TURA, SM
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Tricyclic Antidepressant Toxicosis
Veterinary Clinics of North America: Small Animal Practice, 1990Accidental ingestions of TCAs by companion animals often occur. During the past 4 years, over 450 cases have been reported to the IAPIC. At least 7% of the animals that displayed clinical signs of toxicosis eventually died. Overdoses of TCAs adversely affect the cardiovascular, parasympathetic, and central nervous systems.
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