Results 31 to 40 of about 85,814 (252)

Exposure to CYP2C19‐metabolized drugs following acute stroke: A longitudinal cohort study to inform implementation of CYP2C19 genotype testing

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Cytochrome P450 2C19 (CYP2C19) genotype testing is recommended to guide antiplatelet selection after ischaemic stroke and transient ischaemic attack. CYP2C19 also metabolizes several commonly prescribed non‐antiplatelet drugs. We aimed to quantify exposure to CYP2C19‐metabolized drugs in stroke patients at hospital discharge and during ...
Cleodie C. Swire   +3 more
wiley   +1 more source

Considerations for the use of anesthesia in patients undergoing tricyclic antidepressant treatment

open access: yesMedisur, 2017
Patients undergoing tricyclic antidepressant treatment given anesthesia have experienced the hypotensive effects of both drugs. Traditionally it was recommended to suspend these drugs until two weeks before surgery; however, it is currently proposed that
Iván Hamyd Salazar Carrera
doaj   +2 more sources

Imipramine-induced mania in a child diagnosed with attention-deficit/hyperactivity disorder (ADHD): a case report

open access: yesPsychiatry and Clinical Psychopharmacology, 2018
Children and adolescents treated with antidepressants (ADs) are at higher risk for developing hypomania and mania compared with adults. It was suggested that AD-induced mania represent a predisposition to bipolar disorder (BD) so it may accelerate the ...
Çiğdem Yektaş, Ali Evren Tufan
doaj   +1 more source

Duloxetine-induced rapid eye movement sleep behavior disorder: a case report

open access: yesBMC Psychiatry, 2017
Background Tricyclic antidepressants and selective serotonin reuptake inhibitors have been reported to induce the symptoms of rapid eye movement (REM) sleep behavior disorder (RBD) or to exacerbate REM sleep without atonia.
Lu Tan   +6 more
doaj   +1 more source

Are antidepressants addictive? a literature review

open access: yesEuropean Psychiatry, 2023
Introduction Nowadays, the rates of antidepressant prescription are high and increasing. In this context, the issue of whether these medications are addictive has been increasingly discussed.
M. Turki   +7 more
doaj   +1 more source

Incident low‐dose quetiapine use in adults newly diagnosed with depression in primary care: A nationwide register‐based study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to investigate the incidence of low‐dose quetiapine initiation and associated factors in adults newly diagnosed with depression in primary care. Methods We obtained medication dispensing records, primary and secondary care diagnoses and employment status for antipsychotic‐naïve individuals aged 16–65 newly diagnosed with ...
Laura Purra   +5 more
wiley   +1 more source

Synthesis of Novel, Potentially Biologically Active Dibenzosuberone Derivatives

open access: yesMolecules, 2005
Novel representatives of the important group of biologically active dibenzosuberone derivatives were prepared: 3,7-dibromo-5-(dimethylaminoethyl- oxyimino)-10,11-dihydro-5H-dibenzo[a,d]cyclohepta-1,4-diene (1), 3,7-dibromo-5-(3- dimethylaminopropylidene)-
Vladimir Vinkovic   +3 more
doaj   +1 more source

Rates of prescription of Tricyclic Antidepressants (TCA) and Selective Serotonin Reuptake Inhibitors (SSRI) in children.

open access: yes, 2013
Rates of prescription of Tricyclic Antidepressants (TCA) and Selective Serotonin Reuptake Inhibitors (SSRI) in children.
Irwin Nazareth (144882)   +2 more
core   +1 more source

Gabapentin as an add‐on analgesic to morphine in paediatric patients with chronic pain

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Off‐label use of gabapentin for the treatment of chronic pain in children has increased over the last decade, with multiple clinical trials evaluating its role pain management and potential opioid‐sparing effects. To date, however, these studies appear to rely on empirical evidence without further consideration of pharmacokinetic‐pharmacodynamic ...
Paul Healy   +15 more
wiley   +1 more source

Column liquid chromatography of tricyclic antidepressants

open access: yes, 1977
A column liquid chromatographic system for the analysis of tricyclic antidepressants in serum is described. A high separation efficiency can be obtained with a mixture of ethyl acetate, n-hexane and methylamine as eluent on a silica gel column.
Th.A. Plomp   +7 more
core   +1 more source

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