Electrophilic trifluoromethylthiolation of thiols with trifluoromethanesulfenamide
RSC Advances, 2015 Efficient and highly selective, metal-free, acid promoted synthesis of trifluoromethyl disulfides from thiols and PhNHSCF 3 is described.
Marjan Jereb, Darko Dolenc
openaire +2 more sources
, 2018 This report describes a new method for three-component difluoroalkylation and trifluoromethylthiolation/trifluoromethylselenolation of π-bonds via air-stable SCF3 and SeCF3 reagents as free-radical initiators of ethyl iododifluoroacetate.
Yu-Hua Wen +4 more
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Transition-Metal-Free ipso-Trifluoromethylthiolation of Lithium Aryl Boronates
, 2019 A transition-metal-free direct trifluoromethylthiolation of the ipso-carbon of lithium aryl boronates with trifluoromethanesulfenate under mild conditions was described.
Hanliang Zheng (1633420) +4 more
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Direct α-Trifluoromethylthiolation of Carboxylic Acids Enabled by Boron Catalysis
, 2023 A boron-catalyzed direct a-trifluoromethylthiolation of carboxylic acids was developed. Catalytically generated boron enediolates reacts with electrophilic SCF3 reagent, N-SCF3-phthalimide, to provide a-SCF3 carboxylic acids without the need of substrate
Masaya Sawamura +7 more
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Metal-Free Direct Trifluoromethylthiolation of Aromatic Compounds Using Triptycenyl Sulfide Catalyst [PDF]
Kurose R., Nishii Y., Miura M.. Metal-Free Direct Trifluoromethylthiolation of Aromatic Compounds Using Triptycenyl Sulfide Catalyst. Organic Letters. 23(6), 2380-2385, (2021), 19 March 2021; ©2021 American Chemical Society. https://doi.org/10.1021/acs.
Kurose, Ryo +2 more
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Copper-mediated Trifluoromethylthiolation of Alkenyl Iodides with AgSCF₃ [PDF]
A copper-mediated trifluoromethylthiolation of alkenyl iodides with AgSCF₃ has been developed. CuSCF₃ species generated in-situ from a copper salt and AgSCF₃ can be coupled with alkenyl iodides to produce the corresponding trifluoromethylthioalkenes ...
Kojima, Yuki, Hirano, Koji
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Novel Use of CF3SO2Cl for the Metal-Free Electrophilic Trifluoromethylthiolation
, 2016 The regioselective trifluoromethylthiolation of indole derivatives was achieved under reductive conditions with trifluoromethanesulfonyl chloride as the readily available source of electrophilic SCF3 and a phosphine as the reducing agent.
Hélène Chachignon (2628964) +4 more
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Direct copper-catalyzed oxidative trifluoromethylthiolation of aryl boronic acids with AgSCF3
, 2017 A copper-catalyzed direct oxidative trifluoromethylthiolation of aryl boronic acids with AgSCF3 has been developed.
Biyun Wang, Song Cao, Wei Wu, Xinfei Ji
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Highly ortho-Selective Trifluoromethylthiolation Reactions using a Ligand Exchange Strategy
, 2014 The trifluoromethylthio group (-SCF3) is a highly privileged modifier for drug molecules. Direct C-H trifluoromethylthiolation reactions are highly valuable synthetic tools for the late-stage modification of drug candidates, which have so far been ...
Yong Huang +5 more
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Rh(III)-Catalyzed Trifluoromethylthiolation of Indoles via C-H Activation
, 2015 Cp*Rh(III) complexes have been applied as efficient catalysts for the C-H activation and trifluoromethylthiolation of indoles functionalized with a heterocycle.
Fang Xie (103933) +8 more
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