Results 21 to 30 of about 73,031 (218)

Alterations in Metabolic Status and Headshaking Behavior Following Intravenous Administration of Hypertonic Solutions in Horses with Trigeminal-Mediated Headshaking

open access: yesAnimals, 2018
Trigeminal-nerve-mediated headshaking represents a major welfare challenge for owners and veterinarians and is caused by a low threshold firing of the trigeminal nerve resulting in pain manifested as violent head jerking that often terminates the horse ...
Shara Sheldon   +5 more
doaj   +1 more source

Synaptic connectivity of the TRPV1-positive trigeminal afferents in the rat lateral parabrachial nucleus

open access: yesFrontiers in Cellular Neuroscience, 2023
Recent studies have shown a direct projection of nociceptive trigeminal afferents into the lateral parabrachial nucleus (LPBN). Information about the synaptic connectivity of these afferents may help understand how orofacial nociception is processed in ...
Su Bin An   +4 more
doaj   +1 more source

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

open access: yesAdvanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu   +5 more
wiley   +1 more source

Increase of glutamate in satellite glial cells of the trigeminal ganglion in a rat model of craniofacial neuropathic pain

open access: yesFrontiers in Neuroanatomy, 2023
IntroductionSatellite glial cells (SGCs) that envelop the cell bodies of neurons in sensory ganglia have been shown to both release glutamate, and be activated by glutamate in the context of nociceptive signaling.
Yi Sul Cho   +7 more
doaj   +1 more source

Trigeminal and facial branchiomotor neurons have shared muscle targets in zebrafish larvae. [PDF]

open access: yesJ Anat
Cranial nerve innervation map, based on previous studies, shows the trigeminal and facial motor nerves confined to the mandibular and hyoid arch muscles, respectively, except for the trigeminal nerve in the interhyoideus muscle (M.IH). The revised cranial nerve innervation map, based on this study, shows the facial nerve in the intermandibularis ...
Ghosal R, McArthur KL, Eberhart JK.
europepmc   +2 more sources

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Trigeminal Contributions to the Dorsal Cochlear Nucleus in Mouse

open access: yesFrontiers in Neuroscience, 2021
The dorsal cochlear nucleus (DCN) is the first site of multisensory integration in the auditory pathway of mammals. The DCN circuit integrates non-auditory information, such as head and ear position, with auditory signals, and this convergence may ...
Timothy S. Balmer, Laurence O. Trussell
doaj   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

open access: yesAdvanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang   +11 more
wiley   +1 more source

Trigeminal somatosensation in the temporomandibular joint and associated disorders

open access: yesFrontiers in Pain Research
The temporomandibular joint (TMJ) consists of bone, cartilage, ligaments, and associated masticatory muscles and tendons that coordinate to enable mastication in mammals.
Sienna K. Perry, Joshua J. Emrick
doaj   +1 more source

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