Results 141 to 150 of about 680,951 (211)
Hijacked and educated by HNSCC cells, HLA‐DR+ Schwann cells lost their normal neural‐related functions but acquired immunoregulatory phenotypes to promote CD4+ T cells transform into Tregs. HLA‐DR+ Schwann cells induced a macrophage subpopulation, Il1β.
Xiaoyan Meng +7 more
wiley +1 more source
ABSTRACT The interradicular course of the inferior alveolar nerve represents a significant challenge for oral surgeon. In this context, ultrasonic surgery may provide a precise and safe alternative for sectioning of impacted third molar roots, particularly in procedures involving mandibular molars with an interradicular course of the inferior alveolar ...
Antonio Scarano +3 more
wiley +1 more source
This review integrates three hierarchical frameworks—ascending reticular activating system (ARAS), mesocircuit hypothesis, and intrinsic connectivity networks (ICNs)—to update the neural mechanisms of disorders of consciousness (DoC). We highlight emerging evidence for glutamatergic ARAS pathways, a bidirectional GPi–GPe mesocircuit regulating ...
Yichen Zhou +7 more
wiley +1 more source
Using rabies‐based monosynaptic retrograde tracing and AAV anterograde labeling, this study maps the brain‐wide inputs and outputs of PVN CRH neurons, identifying them as a key hub coordinating stress, autonomic, and behavioral responses. ABSTRACT Objective The paraventricular nucleus of the hypothalamus (PVN) is a central hub integrating ...
Ziteng Yue +11 more
wiley +1 more source
Cancer‐related pain: A bidirectional modulator of cancer progression
CRP and tumour progression engage in a dynamic, bidirectional circuit mediated by multiple mechanisms involving neuroimmunology and cancer ‐neuroscience. Analgesic interventions may affect tumour progression, while anticancer therapies can influence pain. Targeting pain in cancer may have promising therapeutic value in cancer progression.
Junzhe He +5 more
wiley +1 more source
The Olive Oil Mill as Circular Hub
Olive oil production generates large amounts of by‐products at every stage of the production process. The olive mill can be considered a circular hub, where such by‐products are valorized through a cascade approach that first recovers valuable compounds and then converts the remaining biomass into renewable energy.
Sofia Zantedeschi +16 more
wiley +1 more source
Clinical Statistics of Iatrogenic Trigeminal Nerve Injury
Hiroyoshi YAMAMOTO +9 more
openaire +2 more sources
Abstract Background Trigeminal‐mediated headshaking (TMHS) in horses shares clinical features with human trigeminal neuralgia (HTN). Increased levels of the neuropeptide calcitonin gene‐related peptide (CGRP) have been found in the blood and cerebrospinal fluid (CSF) of HTN patients. Inhibition of CGRP in humans has shown promise for pain relief.
Lisa Annabel Weber +7 more
wiley +1 more source
Passive ASO association with NSC‐EVs enhances neuronal uptake and CNS accumulation. NSC‐EV‐ASOs suppress pathogenic targets in ALS cellular models and, following intranasal administration, delay disease onset and improve motor function in SOD1‐G93A mice. These findings provide proof‐of‐concept evidence supporting NSC‐EVs as a platform for enhancing CNS
Yaochao Zheng +8 more
wiley +1 more source
Nerve Growth Factor Treatment and the Corneal Epithelium: Extracellular Vesicle‐Mediated Signaling
ABSTRACT Recombinant human nerve growth factor (NGF) is used to treat patients with impaired corneal wound healing. NGF exerts its effects through complex signaling processes initiated by the binding of one of two cell membrane receptors—TrkA and p75NTR.
Levi N. Kanu +8 more
wiley +1 more source

