Results 51 to 60 of about 29,543 (224)
13. Trigeminal Neuralgia. [PDF]
Pain PractABSTRACTIntroductionTrigeminal neuralgia (TN) is a disorder characterized by recurrent, unilateral brief electric shock‐like pains, abrupt in onset and termination, limited to the distribution of one or more branches of the trigeminal nerve, and triggered by innocuous stimuli.MethodsThe literature on the diagnosis and treatment of TN was retrieved and ...
Snel BJ +6 more
europepmc +4 more sources
Radiofrequency thermocoagulation of Gasserian ganglion in trigeminal neuralgia
Journal of Education, Health and SportIntroduction: Trigeminal neuralgia (TN) is a form of neuropathic pain that targets the fifth cranial nerve, leading to intense facial pain that can significantly impact one’s quality of life.
Natalia Maria Rulewska +10 more
doaj +1 more source
Familial classic trigeminal neuralgia
Neurología (English Edition), 2019 Introduction: The classic form of trigeminal neuralgia is usually sporadic (no familial clustering). However, around 2% of all cases of trigeminal neuralgia may be familial. Describing this entity may be useful for diagnosing this process and may also be
B. Fernández Rodríguez +6 more
doaj +1 more source
A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia
Advanced Science, EarlyView.A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun +11 more
wiley +1 more source
Grading the intensity of nondental orofacial pain: Identification of cutoff points for mild, moderate, and severe pain [PDF]
, 2015 Background: When assessing pain in clinical practice, clinicians often label pain as mild, moderate, and severe. However, these categories are not distinctly defined, and are often used arbitrarily.
Brailo, V, Zakrzewska, JM
core +2 more sources
Current Treatment Options in Neurology, 1999 The initial treatment for trigeminal neuralgia is medical. Carbamazepine is the drug of choice. If the patient proves to be intolerant of carbamazepine, a number of second-line drugs are available, though data on their relative efficacy are nonexistent. Phenytoin, baclofen, clonazepam, and sodium valproate are all worthy of consideration. Oxcarbazepine
+10 more sources
British Journal of Clinical Pharmacology, EarlyView.Aim To evaluate the effects of carbamazepine, a strong cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader. Methods This was a phase 1, open‐label, fixed‐sequence, two‐period study in healthy adult participants.
Hechuan Wang +7 more
wiley +1 more source
The role of Nav1.9 channel in the development of neuropathic orofacial pain associated with trigeminal neuralgia [PDF]
, 2015 BACKGROUND: Trigeminal neuralgia is accompanied by severe mechanical, thermal and chemical hypersensitivity of the orofacial area innervated by neurons of trigeminal ganglion (TG).
Kopach, O +3 more
core +1 more source
Using Diffusion Tensor Imaging to Evaluate Microstructural Changes and Outcomes after Radiofrequency Rhizotomy of Trigeminal Nerves in Patients with Trigeminal Neuralgia. [PDF]
PLoS ONE, 2016 Trigeminal neuralgia is characterized by facial pain that may be sudden, intense, and recurrent. Our aim was to investigate microstructural tissue changes of the trigeminal nerve in patients with trigeminal neuralgia resulting from neurovascular ...
Shu-Tian Chen +5 more
doaj +1 more source
MRIMS Journal of Health Sciences, 2021 Background: There is no clarity in diagnostic criteria of trigeminal neuralgia, and hence, the diagnosis is difficult and often delayed. Therefore, the patient has to visit many clinics before the final and correct diagnosis is established.
Rajesh R Raykar, Sibhi Ganapathy
doaj +1 more source