Results 61 to 70 of about 29,871 (227)

HLA genotype testing for carbamazepine, oxcarbazepine and eslicarbazepine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway, Cinzia Dello Russo, Nicholas Bass, Elvira Bramon, Helen Cross, Natalie Curley, Sarah Curran, Helen Davies, Jana De Villiers, William Evans, Bernhard Frank, Alice Groves, Judith Hayward, Jon Higham, Dyfrig A. Hughes, Shwe Sin Kyaw, Anthony G. Marson, Ailsa McLellan, Seth Mensah, Francis O'Neill, Jane Sargison, Sanjay M. Sisodiya, Jill Swan, Joanna M. Zakrewska, Munir Pirmohamed   +24 more
wiley   +1 more source

Improvement of Trigeminal Neuralgia Following Endoscopic Third Ventriculostomy in a Patient With Normal Pressure Hydrocephalus: A Case Report and Review of the Literature

Acta Medica Iranica, 2020
Normal-pressure hydrocephalus (NPH) has rarely been reported to be associated with trigeminal neuralgia (TN). We report a case of NPH with trigeminal neuralgia, whose symptoms completely resolved after endoscopic third ventriculostomy.
Mohamadreza Hajiabadi, Babak Babakhani, Mostafa Farzin, Sara Tavakolizadeh   +3 more
doaj   +1 more source

The role of Nav1.9 channel in the development of neuropathic orofacial pain associated with trigeminal neuralgia [PDF]

, 2015
BACKGROUND: Trigeminal neuralgia is accompanied by severe mechanical, thermal and chemical hypersensitivity of the orofacial area innervated by neurons of trigeminal ganglion (TG).
Kopach, O, Luiz, AP, Santana-Varela, S, Wood, JN   +3 more
core   +1 more source

Novel planning pipeline utilizing the Surgical Theater system for pediatric epilepsy surgery

Epilepsia Open, EarlyView.
Abstract Objective Advances in the analysis and collation of radiographic datasets have enhanced presurgical planning for various neurosurgical procedures, including clipping of cerebral aneurysms, surgical resection of tumors, and arteriovenous malformation management.
Lisa B. E. Shields, Hunain Abri, Cemal Karakas, Shannon D. Davis, Ian S. Mutchnick   +4 more
wiley   +1 more source

Trigeminal neuralgia

Current Treatment Options in Neurology, 1999
The initial treatment for trigeminal neuralgia is medical. Carbamazepine is the drug of choice. If the patient proves to be intolerant of carbamazepine, a number of second-line drugs are available, though data on their relative efficacy are nonexistent. Phenytoin, baclofen, clonazepam, and sodium valproate are all worthy of consideration. Oxcarbazepine
  +10 more sources

Evidence of descending inhibition deficits in atypical but not classical trigeminal neuralgia [PDF]

, 2009
: Trigeminal neuralgia (TN) is a rare neuropathic facial pain disorder. Two forms of TN, classical TN (CTN) and atypical TN (ATN), are reported and probably have different aetiologies. The aim of the present study was to evaluate the functional integrity
Blanchard, Jocelyn, Goffaux, Philippe, Léonard, Guillaume, Marchand, Serge, Mathieu, David   +4 more
core   +2 more sources

Calcitonin gene‐related peptide concentration in cerebrospinal fluid and serum in horses affected by trigeminal‐mediated headshaking

Equine Veterinary Journal, EarlyView.
Abstract Background Trigeminal‐mediated headshaking (TMHS) in horses shares clinical features with human trigeminal neuralgia (HTN). Increased levels of the neuropeptide calcitonin gene‐related peptide (CGRP) have been found in the blood and cerebrospinal fluid (CSF) of HTN patients. Inhibition of CGRP in humans has shown promise for pain relief.
Lisa Annabel Weber, Hilke Oltmanns, Ludovica Chiavaccini, Kirstie J. Pickles, Veronica Roberts, Tanja Kloock, Tobias Niebuhr, Karsten Feige   +7 more
wiley   +1 more source

Evaluation of Sleep Quality, Depression and Anxiety Levels in Trigeminal Neuralgia Patients

Türk Uyku Tıbbı Dergisi, 2018
Objective: Trigeminal neuralgia is one of the most common causes of chronic neuropathic facial pain. Psychiatric and psychosocial disorders such as especially depression, anxiety disorder and sleep disorders are more frequent in patients with trigeminal ...
Ahmet Taylan Çebi
doaj   +1 more source

Trigeminal neuralgia: An overview from pathophysiology to pharmacological treatments

Molecular Pain, 2020
The trigeminal nerve (V) is the fifth and largest of all cranial nerves, and it is responsible for detecting sensory stimuli that arise from the craniofacial area. The nerve is divided into three branches: ophthalmic (V1), maxillary (V2), and mandibular (
Eder Gambeta, Juliana G. Chichorro, Gerald W. Zamponi   +2 more
doaj   +1 more source

Using Diffusion Tensor Imaging to Evaluate Microstructural Changes and Outcomes after Radiofrequency Rhizotomy of Trigeminal Nerves in Patients with Trigeminal Neuralgia. [PDF]

PLoS ONE, 2016
Trigeminal neuralgia is characterized by facial pain that may be sudden, intense, and recurrent. Our aim was to investigate microstructural tissue changes of the trigeminal nerve in patients with trigeminal neuralgia resulting from neurovascular ...
Shu-Tian Chen, Jen-Tsung Yang, Mei-Yu Yeh, Hsu-Huei Weng, Chih-Feng Chen, Yuan-Hsiung Tsai   +5 more
doaj   +1 more source