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Topical treatment of peripheral neuropathic pain: applying the evidence [PDF]
Patients with peripheral neuropathic pain (NP) may only achieve partial pain relief with currently recommended first-line oral treatments, which are also associated with systemic adverse events.
Cruccu, Giorgio, Sommer, Claudia
core +1 more source
Radiofrequency thermocoagulation of Gasserian ganglion in trigeminal neuralgia
Introduction: Trigeminal neuralgia (TN) is a form of neuropathic pain that targets the fifth cranial nerve, leading to intense facial pain that can significantly impact one’s quality of life.
Natalia Maria Rulewska+10 more
doaj +1 more source
Among the pain syndromes caused by damage to cranial nerves, trigeminal nerve pathology occupies the main place. Trigeminal neuralgia is an exhausting condition characterized by acute shooting recurrent pain in the face.
V.V. Smolanka
doaj
Trigeminal-mediated headshaking is an idiopathic neuropathic facial pain syndrome in horses. There are clinical similarities to trigeminal neuralgia, a neuropathic facial pain syndrome in man, which is usually caused by demyelination of trigeminal ...
Veronica L. Roberts+3 more
doaj +1 more source
White matter microstructural abnormalities in the brainstem trigeminal fibers are a common characteristic of treatment nonresponse across different subtypes of trigeminal neuralgia.
Sarasa Tohyama+4 more
semanticscholar +1 more source
Low-dose Fosphenytoin for Aborting Acute Trigeminal Neuralgia Pain: A Case Report
Introduction: While the typical treatment for trigeminal neuralgia is carbamazepine, the dose must be gradually titrated over time to achieve pain control, which makes the drug a less than ideal candidate for treatment for acute exacerbation of pain due ...
Jamie Baydoun, Alexander Lin, Jared Miya
doaj +1 more source
The role of Nav1.9 channel in the development of neuropathic orofacial pain associated with trigeminal neuralgia [PDF]
BACKGROUND: Trigeminal neuralgia is accompanied by severe mechanical, thermal and chemical hypersensitivity of the orofacial area innervated by neurons of trigeminal ganglion (TG).
Kopach, O+3 more
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Schwann cells and trigeminal neuralgia
Schwann cells are components of the peripheral nerve myelin sheath, which supports and nourishes axons. Upon injury of the trigeminal nerve, Schwann cells are activated and cause trigeminal neuralgia by engulfing the myelin sheath and secreting various ...
Jia-Yi Liao+3 more
semanticscholar +1 more source
Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova+5 more
wiley +1 more source
Familial classic trigeminal neuralgia
Introduction: The classic form of trigeminal neuralgia is usually sporadic (no familial clustering). However, around 2% of all cases of trigeminal neuralgia may be familial. Describing this entity may be useful for diagnosing this process and may also be
B. Fernández Rodríguez+6 more
doaj +1 more source