Results 81 to 90 of about 29,543 (224)

Kolmiknärvineuralgiaga patsientide operatsioonijärgse elukvaliteedi muutuse hindamine [PDF]

, 2017
Taust ja eesmärgid. Kolmiknärvineuralgia on väga tugevat valu põhjustav ja elukvaliteeti halvendav haigus. Uurisime võrdlevalt selle raviks kasutatava mikrovaskulaarse dekompressiooni (MVD) ja kolmiknärvi ganglioni glütserooliblokaadi (GB) tõhusust ning ...
Asser, Andres, Asser, Toomas, Avi, Allan, Braschinsky, Mark, Vetkas, Artur   +4 more
core   +2 more sources

Tic douloureux in patients with incidental intracranial meningioma; MR findings and review of literature

The Egyptian Journal of Radiology and Nuclear Medicine, 2015
Patients with trigeminal neuralgia undergo various investigations in-order to rule-out suspected underlying causes. MRI has proven to be the imaging modality of choice when trigeminal nerve pathology is suspected; it also provides useful guidance in ...
A. Elsotouhy, A. Awad
doaj   +1 more source

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

MedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai, Chongxiang Wang, Ping Jiang, Xiaopeng Mei   +3 more
wiley   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

British Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang, Sijia Zhu, Na Xing, Zhen Zhou, Jiayi Chen, Tianen Si, Mingrui Li, Lin Jia, Yousef Rastegar‐Kashkooli, Tom J. Wang, Wei Zhu, Jing Li, Chao Jiang, Junmin Wang, Moxin Wu, Xiaoping Yin, Weidong Zang, Jian Wang, Songxue Su   +18 more
wiley   +1 more source

Altered autonomic nervous system reactivity to pain in trigeminal neuralgia [PDF]

, 2015
BACKGROUND: In the last two decades, there has been increasing evidence to suggest that trigeminal neuralgia (TN) may be linked to a dysfunction of the autonomic nervous system (ANS).
Chalaye, Philippe, Gaumond, Isabelle, Goffaux, Philippe, Léonard, Guillaume, Marchand, Serge, Mathieu, David   +5 more
core   +2 more sources

Investigating the causal impact of gut microbiota on trigeminal neuralgia: a bidirectional Mendelian randomization study

Frontiers in Microbiology
BackgroundThe etiology and pathogenesis of trigeminal neuralgia remain unclear. This study examines the connection between gut microbiota and trigeminal neuralgia using Mendelian randomization analysis to provide insights into the disorder’s origin and ...
Chuan Zeng, Chaolong Zhang, Yuxuan Jia, Huaiyu Zhou, Chunming He, Haimin Song   +5 more
doaj   +1 more source

Antiepileptic drugs for the treatment of neuropathic pain : a systematic review [PDF]

, 2012
Many therapies have been proposed for the management of neuropathic pain, and they include the use of different antiepileptic drugs. However, the lack of high quality studies indicates that results on the different neuropathic disorders under study ...
Gay Escoda, Cosme, Sanmartí García, Gemma, Vargas Espinosa, M.L., Vázquez Delgado, Eduardo   +3 more
core   +1 more source

Postherpetic Neuralgia and Trigeminal Neuralgia [PDF]

Pain Research and Treatment, 2017
Postherpetic neuralgia (PHN) is an unpredictable complication of varicella zoster virus- (VZV-) induced herpes zoster (HZ) which often occurs in elderly and immunocompromised persons and which can induce psychosocial dysfunction and can negatively impact on quality of life. Preventive options for PHN include vaccination of high-risk persons against HZ,
L. Feller, R. A. G. Khammissa, J. Fourie, M. Bouckaert, J. Lemmer   +4 more
openaire   +2 more sources

Neuropsychiatric Disorders and Constipation: Unraveling Causal Links Through Genetic Analysis

Brain and Behavior, Volume 16, Issue 3, March 2026.
This study employed bidirectional two‐sample Mendelian randomization to explore the causal relationships between 12 neuropsychiatric disorders and constipation. Anxiety and depression might increase the risk of constipation, while constipation elevates the risks of anxiety, depression, epilepsy, and trigeminal neuralgia, emphasizing attention to ...
Guojie Zhao, Haixia Ren, Yi Zhang, Zhi Wang, Qiao Yang, Shuang Liu, Minzhen Li, Zhiyu Xiang, Jingwen Liu   +8 more
wiley   +1 more source

Amitriptyline Induced Life‐Threatening Steven–Johnson Syndrome: Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Stevens–Johnson syndrome is one of the few dermatological emergencies in clinical practice. The syndrome is often secondary to the usage of drugs, of which allopurinol, penicillins, sulfa drugs, ibuprofen, sodium valproate, phenytoin, lamotrigine, and carbamazepine are commonly implicated.
Wondwosen Mengist Dereje, Lidya Yalew, Nardos Tafesse, Teklegiorgis Goshime Getachew   +3 more
wiley   +1 more source