Results 91 to 100 of about 1,569,115 (301)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Comparison of the Effectiveness of Blinded Versus Ultrasound-Guided Trigger Point Injections into the Trapezius Muscle in Patients with Fibromyalgia

İstanbul Medical Journal
Introduction: The primary objectives of treating fibromyalgia syndrome (FMS), which frequently coexists with myofascial pain syndrome (MPS), are to deactivate trigger points, alleviate pain, and remove factors that exacerbate the condition. Recently, the
Muhammet Şahin Elbastı, Songül Bağlan Yentür   +1 more
doaj   +1 more source

A Reply to “Option Value of Harvesting†Revisited (The Comment) [PDF]

Li’s results (1998) are correct and robust. The Comment offers an interesting perspective from real-options theory, albeit misguided--from a resource-economics point of view.
Li, Eric A.L.
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Performance of the EUDET-type beam telescopes

, 2016
Test beam measurements at the test beam facilities of DESY have been conducted to characterise the performance of the EUDET-type beam telescopes originally developed within the EUDET project.
Behr, J., Bulgheroni, A., Claus, G., Corrin, E., Cussans, D. G., Dreyling-Eschweiler, J., Eckstein, D., Eichhorn, T., Goffe, M., Gregor, I. M., Haas, D., Jansen, H., Muhl, C., Perrey, H., Peschke, R., Roloff, P., Rubinskiy, I., Spannagel, S., Winter, M.   +18 more
core   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Evaluation of the inter-examiner reliability of myofascial trigger point identification in dogs

Frontiers in Veterinary Science
IntroductionMyofascial trigger points (MTrPs) are a source of chronic pain in humans, but their diagnosis relies on subjective manual palpation. MTrP distribution has been described in dogs, but reliability between examiners remains unknown.
Bryce Talsma Roberts, Christina Montalbano, Felix Michael Duerr, Karolynn Mireya Ellis, Lindsay Hochman Elam   +4 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Are There Any Redshift >8 Gamma-Ray Bursts in the BATSE Catalog?

, 2007
Several luminosity indicators have been found for Gamma-Ray Bursts (GRBs) wherein measurable light curve and spectral properties are well-correlated with the peak luminosity.
Bradley E. Schaefer, Firmani C., Li L.-X., Teresa Ashcraft, Totani T.   +4 more
core   +1 more source