Results 121 to 130 of about 1,569,115 (301)

The changing role of house price dynamics over the business cycle [PDF]

open access: yes
In this paper, we attempt to analyse the relationship between house price developments and the business cycle. Employing a time-varying transition probability Markov switching framework, we provide empirical evidence that house price growth may prove a ...
Dufrénot, G., Malik, S.
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Comparative effectivenesss of dry needling and deep friction massage in myofascial pain syndrome: an original research

open access: yesВестник восстановительной медицины
Introduction. Myofascial Pain Syndrome (MPS) is a common condition that limits mobility and causes chronic pain. While myofascial trigger points are recognized as key contributors, the most effective treatments remain debated.
Dies Izah Qonita   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Quantitative proteomics analysis to identify biomarkers of chronic myofascial pain and therapeutic targets of dry needling in a rat model of myofascial trigger points

open access: yesJournal of Pain Research, 2019
Li-Hui Li,1,2 Qiang-Min Huang,1 Marco Barbero,2 Lin Liu,3 Thi-Tham Nguyen,4 Matteo Beretta-Piccoli,2 An-Le Xu,1 Li-Juan Ji1 1Department of Sport Medicine and Rehabilitation Center, Shanghai University of Sport, Shanghai, China; 2Rehabilitation Research ...
Li L   +7 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Study of effect of acupuncture on Shoulder trigger points in patients with Myofascial pain syndrome

open access: yesطب جانباز, 2010
Background: Trigger Points (TrPs) appear to be common among patients with clinically significant musculoskeletal pain. These points include circumscribed spot tenderness in a nodule that is part of a palpably tense band of muscle fibers.
A. Amanelahi   +2 more
doaj  

Dry needling in the management of chronic tension‐type headache associated with levator scapulae syndrome: A case report

open access: yesClinical Case Reports
Key Clinical Message The use of DN to the muscular trigger points and distal periosteal enthesis of the levator scapulae may be a useful adjunct intervention within a multi‐modal plan of care for the management of work‐related chronic tension‐type ...
Peter Gagnon   +6 more
doaj   +1 more source

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