Results 1 to 10 of about 472,656 (344)

Triglyceride and Triglyceride-Rich Lipoproteins in Atherosclerosis

Frontiers in Molecular Biosciences, 2022
Cardiovascular disease (CVD) is still the leading cause of death globally, and atherosclerosis is the main pathological basis of CVDs. Low-density lipoprotein cholesterol (LDL-C) is a strong causal factor of atherosclerosis. However, the first-line lipid-lowering drugs, statins, only reduce approximately 30% of the CVD risk.
Bai-Hui Zhang, Fan Yin, Ya-Nan Qiao, Shou-Dong Guo   +3 more
openaire   +4 more sources

Validation of an incompletely coupled two-compartment nonrecycling catenary model for turnover of liver and plasma triglyceride in man

Journal of Lipid Research, 1965
Pool sizes and turnover rates of hepatic triglycerides and of lipids of three plasma lipoprotein fractions of human subjects were defined from studies of the rates of incorporation of labeled free glycerol and of labeled palmitate into these lipids, and ...
John W. Farquhar, Richard C. Gross, Roger M. Wagner, Gerald M. Reaven   +3 more
doaj   +2 more sources

Fatty acid esterification and chylomicron formation during fat absorption in rat: III. Positional relations in triglycerides and lecithin

Journal of Lipid Research, 1965
Chylomicron triglyceride and lecithin obtained after feeding mixtures of three or four free fatty acids to rats were hydrolyzed using pancreatic lipase and phospholipase A respectively.
Malcolm Whyte, DeWitt S. Goodman, Arthur Karmen   +2 more
doaj   +2 more sources

Triglyceride Induced Metabolic Inflammation: Potential Connection of Insulin Resistance and Recurrent Pregnancy Loss

Frontiers in Endocrinology, 2021
The underlying correlative mechanisms between Insulin resistance (IR) and recurrent pregnancy loss (RPL) in patients without polycystic ovarian syndrome (PCOS) remain inconclusive.
Yongjie Liu, Mengyang Du, Yuexin Gan, Shihua Bao, Liping Feng, Liping Feng, Jun Zhang   +6 more
doaj   +1 more source

Case Report: Hypertriglyceridemia and Premature Atherosclerosis in a Patient With Apolipoprotein E Gene ε2ε1 Genotype

Frontiers in Cardiovascular Medicine, 2021
We present a case of a 40-year-old male with premature atherosclerosis, with evidence of both eruptive and tendinous xanthomas, which could imply an increase in both low-density lipoprotein (LDL) and triglyceride (TG) levels.
Alena S. Limonova, Alexandra I. Ershova, Alexey N. Meshkov, Anna V. Kiseleva, Mikhail G. Divashuk, Mikhail G. Divashuk, Vladimir A. Kutsenko, Vladimir A. Kutsenko, Oxana M. Drapkina   +8 more
doaj   +1 more source

Triglyceride deposit cardiomyovasculopathy: a rare cardiovascular disorder

Orphanet Journal of Rare Diseases, 2019
Triglyceride deposit cardiomyovasculopathy (TGCV) is a phenotype primarily reported in patients carrying genetic mutations in PNPLA2 encoding adipose triglyceride lipase (ATGL) which releases long chain fatty acid (LCFA) as a major energy source by the ...
Ming Li, Ken-ichi Hirano, Yoshihiko Ikeda, Masahiro Higashi, Chikako Hashimoto, Bo Zhang, Junji Kozawa, Koichiro Sugimura, Hideyuki Miyauchi, Akira Suzuki, Yasuhiro Hara, Atsuko Takagi, Yasuyuki Ikeda, Kazuhiro Kobayashi, Yoshiaki Futsukaichi, Nobuhiro Zaima, Satoshi Yamaguchi, Rojeet Shrestha, Hiroshi Nakamura, Katsuhiro Kawaguchi, Eiryu Sai, Shu-Ping Hui, Yusuke Nakano, Akinori Sawamura, Tohru Inaba, Yasuhiko Sakata, Yoko Yasui, Yasuyuki Nagasawa, Shintaro Kinugawa, Kazunori Shimada, Sohsuke Yamada, Hiroyuki Hao, Daisaku Nakatani, Tomomi Ide, Tetsuya Amano, Hiroaki Naito, Hironori Nagasaka, Kunihisa Kobayashi, on behalf of the Japan TGCV study group   +38 more
doaj   +1 more source

Triglycerides and Cardiovascular Risk [PDF]

Current Cardiology Reviews, 2009
In 1996 a meta-analysis was published showing that an increase in plasma triglyceride (TG) levels was associated with an increase in CHD risk, even after adjustment for high density lipoprotein cholesterol (HDL-C) levels. Very recently, two studies were published that further extent the early observation and showed the importance of nonfasting plasma ...
E. S. Stroes, J. J.P. Kastelein, M. E. Visser, G. M. Dallinga-Thie, K. E.L. Harchaoui   +4 more
openaire   +3 more sources

Knockdown of lnc-KCNC3-3:1 Alleviates the Development of Atherosclerosis via Downregulation of JAK1/STAT3 Signaling Pathway

Frontiers in Cardiovascular Medicine, 2021
Background: Atherosclerosis is a major cause of coronary artery disease (CAD), and CAD is one of the main causes leading to death in most countries. It has been reported that lncRNAs play important roles in the development of atherosclerosis; thus, we ...
Limin Sun, Xin He, Tao Zhang, Guizhou Tao, Xin Wang   +4 more
doaj   +1 more source

Analysis of the risk of cardiovascular diseases among people with diabetes according to triglyceride level

Journal of Advanced Biotechnology and Experimental Therapeutics, 2021
The low percentage of high-density lipoprotein-cholesterol (HDL-C) is strongly accompanied with cardiovascular diseases (CVD) where female are at higher risk than male and are the most dangerous reason of a disease called type 2 diabetes mellitus (T2DM).
Md. Mim Obaidullah, Md. Rayhan Chowdhury, Shirmin Islam, Ashok Kumar Barman, Israt Ara Hossain, Mohammad Nurul Matin   +5 more
doaj   +1 more source

Clinical review on triglycerides [PDF]

European Heart Journal, 2019
AbstractHypertriglyceridaemia is a common clinical problem. Epidemiologic and genetic studies have established that triglyceride-rich lipoproteins (TRL) and their remnants as important contributors to ASCVD while severe hypertriglyceridaemia raises risk of pancreatitis.
Ulrich Laufs, Klaus G Parhofer, Henry N Ginsberg, Robert A Hegele   +3 more
openaire   +2 more sources