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Triglyceride and Triglyceride-Rich Lipoproteins in Atherosclerosis
Frontiers in Molecular Biosciences, 2022 Cardiovascular disease (CVD) is still the leading cause of death globally, and atherosclerosis is the main pathological basis of CVDs. Low-density lipoprotein cholesterol (LDL-C) is a strong causal factor of atherosclerosis. However, the first-line lipid-lowering drugs, statins, only reduce approximately 30% of the CVD risk.
Bai-Hui Zhang +3 more
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Triglycerides and Cardiovascular Risk [PDF]
Current Cardiology Reviews, 2009 In 1996 a meta-analysis was published showing that an increase in plasma triglyceride (TG) levels was associated with an increase in CHD risk, even after adjustment for high density lipoprotein cholesterol (HDL-C) levels. Very recently, two studies were published that further extent the early observation and showed the importance of nonfasting plasma ...
E. S. Stroes +4 more
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Clinical review on triglycerides [PDF]
European Heart Journal, 2019 AbstractHypertriglyceridaemia is a common clinical problem. Epidemiologic and genetic studies have established that triglyceride-rich lipoproteins (TRL) and their remnants as important contributors to ASCVD while severe hypertriglyceridaemia raises risk of pancreatitis.
Ulrich Laufs +3 more
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Triglycerides and Postprandial Angina [PDF]
Circulation, 1998 To the Editor: We read with interest the article by Lundman et al,1 who, using Doppler ultrasound measurements of brachial artery diameter, showed that increasing plasma triglycerides and nonesterified fatty acids (NEFAs) decreases brachial artery reactivity in young, healthy men.
Kearney, M, Cowley, A, Macdonald, I
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Is Triglyceride Atherogenic? [PDF]
Korean Clinical Diabetes, 2009 Fig. 1과 같이 중성지방(TAG) 입자들은 지방세포에 많이 함입되어 저장된다. 당과 같이 저장되는 과정에는 인슐린의 동화작용이 관여하게 된다. 이러한 중성지방은 가수분해되 어 non-esterified fatty acid의 형태로 유리되어 간으로 전달 된다. 특히 인슐린저항성(Fig. 2 중 IR) 상황에서는 카테콜라민 이나 글루코르티코이드 등의 스트레스 호르몬의 자극에 대 해 지방세포가 민감하게 반응하기 때문에 많은 양의 유리지 방산이 생산되며 이는 간으로 흡수되어 중성지방을 만드는 원료로 쓰인다. Fig.
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The triglyceride lipases of the pancreas [PDF]
Journal of Lipid Research, 2002 Pancreatic triglyceride lipase (PTL) and its protein cofactor, colipase, are required for efficient dietary triglyceride digestion. In addition to PTL, pancreatic acinar cells synthesize two pancreatic lipase related proteins (PLRP1 and PLRP2), which have a high degree of sequence and structural homology with PTL. PLRP1 has no known activity.
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TRIGLYCERIDES | Liquid Chromatography
, 2000 Peer ...
Ruiz-Gutiérrez, Valentina +1 more
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The Role of Triglycerides in Atherosclerosis [PDF]
Current Cardiology Reports, 2011 Hypertriglyceridemia is a prevalent risk factor for cardiovascular disease (CVD) and increasingly important in the setting of current obesity and insulin resistance epidemics. High triglyceride (TG) levels are markers for several types of atherogenic lipoproteins.
Frank M. Sacks +2 more
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A stereospecific analysis of triglycerides
Journal of Lipid Research, 1965 AbstractStereospecific analysis determines how the fatty acids of triglycerides are distributed over the three different positions of the glycerol. The special problem is the differentiation of position I‐1 and L‐3 of glycerol. In the presently known methods, triglycerides are first degraded to mixtures of diglycerides, either by the action of a lipase
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Gut triglyceride production [PDF]
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2012 Our knowledge of how the body absorbs triacylglycerols (TAG) from the diet and how this process is regulated has increased at a rapid rate in recent years. Dietary TAG are hydrolyzed in the intestinal lumen to free fatty acids (FFA) and monoacylglycerols (MAG), which are taken up by enterocytes from their apical side, transported to the endoplasmic ...
Xiaoyue Pan, M. Mahmood Hussain
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