Results 211 to 220 of about 5,010,147 (298)

Menopause hormone therapy in women with cardiovascular risk factors or established ischemic heart disease: A joint FIGO and WHF position paper

International Journal of Gynecology &Obstetrics, EarlyView.
Integrated approach to menopausal hormone therapy in women with cardiovascular risk factors or established ischemic heart disease, from early treatment initiation and risk stratification to individualized therapy, multidisciplinary follow‐up, and health‐system recommendations.
Chiara Benedetto, Martha Gulati, Suvarna S. Khadilkar, Angela H. E. M. Maas, Federica Frezet, Gláucia Maria Moraes de Oliveira, Andrea R. Genazzani, Hema Divakar, Athena Poppas, on behalf of the World Heart Federation (WHF) and the International Federation of Gynecology and Obstetrics (FIGO)   +9 more
wiley   +1 more source

Association of C-Reactive Protein-Triglyceride Glucose Index and TyG Index With Prehypertension and Hypertension. [PDF]

Immun Inflamm Dis
Yang S, Zhang Y, Zhou Z, Xu M, Feng L, Zu X.   +5 more
europepmc   +1 more source

Multi‐omics reveals gastrointestinal metabolic disorder‐induced diarrhea in postpartum dairy cows

iMetaOmics, EarlyView.
Nutritional diarrhea is a pervasive, costly challenge in dairy production. Using integrated metagenomic and metabolomic profiling, we identified coordinated microbial and metabolic alterations across the rumen, hindgut, and serum. In the rumen, enrichment of Prevotella sp.
Weixuan Tang, Yangyi Hao, Jiawei Zhang, Yajing Wang, Zhijun Cao, Hongjian Yang, Wei Wang, Shengli Li   +7 more
wiley   +1 more source

The C-Reactive Protein-Triglyceride-Glucose Index and Functional Outcomes in Acute Ischemic Stroke Patients Following Endovascular Thrombectomy. [PDF]

Brain Behav
Bian J, Xu J, Li X, Ding X, Guo Y, Yang K, Huang X, Zhao S, Zhou Z, Li Z.   +9 more
europepmc   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

iNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang, Xinyan Li, Honglu Shi, Gaolei Song, Zhifu Xie, Jingya Li   +5 more
wiley   +1 more source

Hepatocyte‐Centered Regulation of MASH Fibrosis: From Animal Models to Molecular Mechanisms and Targeted Therapies

iNew Medicine, EarlyView.
This review highlights hepatocytes as active regulators of MASH fibrosis through secreted proteins, metabolites, and extracellular vesicles that modulate hepatic stellate cell activation. These hepatocyte–stellate cell communication pathways provide a mechanistic framework for developing targeted antifibrotic therapies, including hepatocyte‐directed ...
Eui Jung Jung, Xiaobo Wang
wiley   +1 more source

Interaction Analysis of <i>VDR</i> rs7975232 Polymorphism and the Triglyceride-Glucose Index in Relation to Metabolic Outcomes in Older Adults. [PDF]

Int J Mol Sci
Michniewicz S, Chmielowiec K, Chmielowiec J, Czyżniewski B, Strowski MZ, Pruszyńska-Oszmałek E, Kołodziejski P, Kowalski MT, Grzywacz A, Gibas-Dorna M.   +9 more
europepmc   +1 more source