Results 191 to 200 of about 162,489 (254)

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

Association of the triglyceride-glucose index with blood pressure and hypertension in a large adult population: A cross-sectional study. [PDF]

SAGE Open Med
Rezaianzadeh A, Mohammed Ali Hussein Alhurry A, Hajihosseini F, Ghoddusi Johari M, Shojaei-Zarghani S, Hosseini SV.   +5 more
europepmc   +1 more source

Pharmacokinetics and Acute Safety Evaluation of Tryptanthrin, A Bioactive Constituent of Indigo naturalis, Following Intravenous Administration in Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The use of Indigo naturalis in treating inflammatory diseases is clinically restricted by severe adverse events, including pulmonary arterial hypertension and hepatotoxicity. Tryptanthrin, a major indoloquinazoline alkaloid of Indigo naturalis, exhibits potent anti‐inflammatory activity; however, its specific safety profile relative to the ...
Hyung Jin Kim, Gabsik Yang, Jun Ho Lee
wiley   +1 more source

Triglyceride-glucose index, genetic predisposition, and incident depression: a prospective cohort study from the UK Biobank. [PDF]

Psychol Med
Hu W, Liu TS, Shen ZZ, Tian G, Jia CX, Liu BP.   +5 more
europepmc   +1 more source

Assessing Metabolic and Reproductive Consequences of Prenatal Paracetamol Exposure in Female CD1 Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Paracetamol is a widely used analgesic during pregnancy; however, emerging evidence suggests it may act as an endocrine/metabolism disrupting compound. Using an F1 female CD1 mouse model, this study scrutinized the long‐term metabolic and reproductive consequences linked to intrauterine paracetamol exposure.
Bita Entezari, Deniz Bozdag, Elif İnce‐Erguc, Aylin Buhur, Cansin Sirin Tomruk, Suna Sabuncuoglu, Altug Yavasoglu, Hande Gurer‐Orhan   +7 more
wiley   +1 more source

C-Reactive Protein-Triglyceride-Glucose Index and Coronary Artery Calcium Progression: A Prospective Cohort Analysis. [PDF]

Clin Cardiol
Hao QY, Li ZH, Weng J, Zhan ZB, Bai KH, Guo JB, Cui XP, Gao JW, Zeng YH.   +8 more
europepmc   +1 more source

Heavy Metal Mixture Exposure and Insulin Resistance in U.S. Adults: The Mediating Role of Systemic Inflammation

Journal of Clinical Laboratory Analysis, EarlyView.
In a nationally representative sample of 3042 U.S. adults from NHANES 2021–2023, blood lead, cadmium, and mercury, both individually and as a weighted quantile sum (WQS) mixture, were inversely associated with insulin resistance assessed by HOMA‐IR. Systemic inflammation, measured by high‐sensitivity C‐reactive protein (hs‐CRP), significantly mediated ...
Cai Zhang, Shidi Lin, Yu Lin
wiley   +1 more source

Association of the Triglyceride-Glucose Index With Gallstone Disease: A Systematic Review and Meta-Analysis of Observational Studies. [PDF]

JGH Open
Gupta N, Katkuri SN, Arcot R, Kumar S, Verma S, Lakhanpal S, Kumar S, Paul JR, Satapathy P, Mawejje E.   +9 more
europepmc   +1 more source

Triglyceride-glucose index and stroke (review of literature)

Russian Clinical Laboratory Diagnostics
openaire   +1 more source

The Role of Serum Uric Acid in the Prediction of Type 2 Diabetes Mellitus: Tehran Lipid and Glucose Study

Journal of Clinical Laboratory Analysis, EarlyView.
This study aimed to examine the association between serum uric acid and incident type 2 diabetes mellitus. The study included 5719 subjects (2588 men) aged ≥ 30 years without T2DM at baseline. Multivariate Cox proportional hazard analyses were applied using SUA as continuous and categorical variables. Subjects followed up during a median follow‐up of 8.
Nahid Kord, Samaneh Asgari, Maryam Tohidi, Somayeh Hosseinpour‐Niazi, Fereidoun Azizi, Farzad Hadaegh   +5 more
wiley   +1 more source