Results 141 to 150 of about 229,067 (324)

Hepatic gluconeogenesis and regulatory mechanisms in lactating ruminants: A literature review

open access: yesAnimal Research and One Health, EarlyView.
phosphoenolpyruvate carboxy kinase, FBP1, and glucose‐6‐phosphatase are key rate‐limiting enzymes that determine the efficiency of gluconeogenesis. The main substrate for gluconeogenesis in the liver of ruminants is propionate, which provides more than 60% of the carbon source for gluconeogenesis.
Guoyan Wang   +5 more
wiley   +1 more source

Upregulation of liver VLDL receptor and FAT/CD36 expression in LDLR−/− apoB100/100 mice fed trans-10,cis-12 conjugated linoleic acid1

open access: yesJournal of Lipid Research, 2006
This study explores the mechanisms responsible for the fatty liver setup in mice fed trans-10,cis-12 conjugated linoleic acid (t10c12 CLA), hypothesizing that an induction of low density lipoprotein receptor (LDLR) expression is associated with lipid ...
Pascal Degrace   +7 more
doaj  

Non-parametric Replication of Instrumental Variable Estimates Across Studies [PDF]

open access: yesarXiv
Replicating causal estimates across different cohorts is crucial for increasing the integrity of epidemiological studies. However, strong assumptions regarding unmeasured confounding and effect modification often hinder this goal. By employing an instrumental variable (IV) approach and targeting the local average treatment effect (LATE), these ...
arxiv  

TRIB3 suppresses milk fatty acids metabolism by inhibiting p‐AKT/PPARG signaling in goat mammary epithelial cells

open access: yesAnimal Research and One Health, EarlyView.
In this study, it revealed that TRIB3 could mediate the transcriptional activity of PPARG, inhibit the phosphorylation of akt, and reduce the expression of lipid metabolism‐related genes, thus inhibiting TAG synthesis and affecting fatty acid composition.
Xinglong Gong   +9 more
wiley   +1 more source

Cardiometabolic Risk Factors in South Asians: An Epidemiological and Anthropological Study in an Urban Populace of Eastern India [PDF]

open access: yesarXiv
Background: This study examines cardiometabolic (CM) risk factors in an urban South Asian population, integrating medical and Anthropological perspectives to explore the effects of socio-economic, lifestyle, gender-specific factors, and cultural norms on health outcomes.
arxiv  

Three-phase liquid extraction: a simple and fast method for lipidomic workflows[S]

open access: yesJournal of Lipid Research, 2019
An unbiased sample preparation free of interferents (i.e., competing analytes, detergents, plastics) is critical to any lipid MS workflow. Here we present a novel three-phase lipid extraction (3PLE) technique using a single-step liquid-liquid extraction (
Gonçalo Vale   +5 more
doaj  

Atherosclerotic Plaque Progression and Incident Cardiovascular Events in a 10‐Year Prospective Study of Patients With Systemic Lupus Erythematosus: The Impact of Persistent Cardiovascular Risk Factor Target Attainment and Sustained DORIS Remission

open access: yesArthritis &Rheumatology, EarlyView.
Objective Cardiovascular disease (CVD) is a leading cause of death in individuals with systemic lupus erythematosus (SLE). We assessed atherosclerotic plaque progression and incident cardiovascular events in patients with SLE over a 10‐year follow‐up.
Nikolaos Papazoglou   +2 more
wiley   +1 more source

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