Results 141 to 150 of about 844,308 (381)
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang +9 more
wiley +1 more source
SPLANCHNIC PRODUCTION AND UPTAKE OF ENDOGENOUS TRIGLYCERIDES IN THE FASTING STATE IN MAN* [PDF]
Lars A. Carlson, Lars‐Göran Ekelund
openalex +1 more source
Cholesterol May be a Negative Whereas Triglycerides Positive Acute Phase Reactants in the Plasma
Mehmet Rami Helvacı +5 more
openalex +1 more source
Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao +21 more
wiley +1 more source
Given the recognized involvement of the gut microbiome in the development of obesity, considerable efforts are being made to discover probiotics capable of preventing and managing obesity.
Jinwook Kim +11 more
doaj +1 more source
Hypertriglyceridemia and preeclampsia: Its physiological role and up-to-date evidence [PDF]
Preeclampsia is a disease with a highincidence for maternal and fetal morbidity and mortality, mainly indeveloping countries. Although its etiology remains unclear, severalstudies have shown that endothelial cell dysfunction plays an important role in ...
María Paula Martínez Linares +1 more
doaj
Microglial lipid metabolic dysfunction drives neurodegeneration in glaucoma. We found loss of LRP1 causes lipid accumulation and inflammation. We developed alpinetin‐loaded nanoparticles (AlpNPs) that bind LRP1, activate the PPARγ‐LXRα‐ABCA1 pathway to restore lipid homeostasis, promote an anti‐inflammatory phenotype, and protect retinal ganglion cells,
Miao Wei +8 more
wiley +1 more source
This study was aimed to investigate the effect of mangosteen rind on the glycogen recovery of themuscle and the liver, and the glucose and the triglyceride consumption during physical activities. ARandomized Block Design was applied with four treatments:
I Nyoman Arsana, Ni Ketut Ayu Juliasih
doaj
Coactivation of Foxa2 through Pgc-1β promotes liver fatty acid oxidation and triglyceride/VLDL secretion [PDF]
Christian Wolfrum, Markus Stoffel
openalex +1 more source
Association between skeletal muscle mass and serum concentrations of lipoprotein lipase, GPIHBP1, and hepatic triglyceride lipase in young Japanese men [PDF]
学位記番号 ...
Matsumoto, Ryutaro +2 more
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