Results 21 to 30 of about 694,820 (288)

Triglyceride [PDF]

open access: yesCirculation, 1998
The relation of serum TG concentrations and risk for CHD has been an issue of great interest and controversy. Unlike analyses with LDL-C and HDL-C, for which very strong and consistent relations with CHD risk have been demonstrated in observational and interventional studies, those with TG are ambiguous. Thus, TG represents a clinical conundrum: should
openaire   +1 more source

Association of Triglyceride-Lowering LPL Variants and LDL-C–Lowering LDLR Variants With Risk of Coronary Heart Disease

open access: yesJournal of the American Medical Association (JAMA), 2019
Importance Triglycerides and cholesterol are both carried in plasma by apolipoprotein B (ApoB)–containing lipoprotein particles. It is unknown whether lowering plasma triglyceride levels reduces the risk of cardiovascular events to the same extent as ...
B. Ference   +15 more
semanticscholar   +1 more source

The Long Term Kinetic of Plasma Lipids and Lipoproteins in Tyloxapol Injected Rats [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: The level of plasma triglyceride is balanced by the rate of secretion into and clearance from the plasma. Tyloxapol (Triton WR1339) is a nonionic detergent that inhibits lipoprotein lipase and hence clearance of triglyceride from the ...
Mehdi Rasouli   +2 more
doaj   +1 more source

Remnants of the Triglyceride-Rich Lipoproteins, Diabetes, and Cardiovascular Disease

open access: yesDiabetes, 2020
Diabetes is now a pandemic disease. Moreover, a large number of people with prediabetes are at risk for developing frank diabetes worldwide. Both type 1 and type 2 diabetes increase the risk of atherosclerotic cardiovascular disease (CVD).
A. Chait   +5 more
semanticscholar   +1 more source

Structural and functional consequences of missense mutations in exon 5 of the lipoprotein lipase gene

open access: yesJournal of Lipid Research, 2002
Missense mutations in exon 5 of the LPL gene are the most common reported cause of LPL deficiency. Exon 5 is also the region with the strongest homology to pancreatic and hepatic lipase, and is conserved in LPL from different species. Mutant LPL proteins
Jonas Peterson   +8 more
doaj   +1 more source

Ethnic differences in hepatic lipase and HDL in Japanese, black, and white Americans

open access: yesJournal of Lipid Research, 2004
Hepatic lipase activity (HLA) is a determinant of HDL levels, and a polymorphism in the hepatic lipase gene (LIPC) promoter (C−514T) has been hypothesized to account for higher HDL in blacks and Japanese compared with whites.
Molly C. Carr   +2 more
doaj   +1 more source

Triglyceride Metabolism in the Liver

open access: yesComprehensive Physiology, 2017
Triglyceride molecules represent the major form of storage and transport of fatty acids within cells and in the plasma. The liver is the central organ for fatty acid metabolism.
M. Alves‐Bezerra, David E Cohen
semanticscholar   +1 more source

Chemically Modifying Vegetable Oils to Prepare Green Lubricants

open access: yesLubricants, 2017
Chemically modifying vegetable oils to produce an alternative to petroleum-based materials is one of the most important emerging industrial research areas today because of the adverse effects of petroleum products on the environment and the shortage of ...
Gobinda Karmakar   +2 more
doaj   +1 more source

The Roles of ApoC-III on the Metabolism of Triglyceride-Rich Lipoproteins in Humans

open access: yesFrontiers in Endocrinology, 2020
Cardiovascular disease (CVD) is the leading cause of death globally. It is well-established based on evidence accrued during the last three decades that high plasma concentrations of cholesterol-rich atherogenic lipoproteins are causatively linked to CVD,
J. Borén, C. Packard, M. Taskinen
semanticscholar   +1 more source

A role for triglyceride lipase brummer in the regulation of sex differences in Drosophila fat storage and breakdown

open access: yesPLoS Biology, 2020
Triglycerides are the major form of stored fat in all animals. One important determinant of whole-body fat storage is whether an animal is male or female.
Lianna W. Wat   +15 more
semanticscholar   +1 more source

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