Results 21 to 30 of about 844,308 (381)

Studies on hepatotoxicity induced by chlorinated hydrocarbons. II. Lipid metabolism and absorption spectrum of microsomal lipid in the mice exposed to 1, 1, 2, 2-tetrachloroethane [PDF]

open access: yes, 1970
Female Cb mice weighing 20-23 g were exposed to 800 ppm (in average) of 1, I, 2, 2.tetrachloroethane for 3 hours. Both triglyceride and phospholipid in the liver and plasma were determined at varying times after the exposure.
Tomokuni, Katsumaro
core   +1 more source

Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome.

open access: yesNew England Journal of Medicine, 2019
BACKGROUND Familial chylomicronemia syndrome is a rare genetic disorder that is caused by loss of lipoprotein lipase activity and characterized by chylomicronemia and recurrent episodes of pancreatitis. There are no effective therapies.
J. Witztum   +18 more
semanticscholar   +1 more source

Use of the triglyceride-glucose index (TyG) in cardiovascular disease patients

open access: yesCardiovascular Diabetology, 2020
Da Silva et al. showed that the triglyceride-glucose (TyG) index was positively associated with a higher prevalence of symptomatic coronary artery disease (CAD). TyG has been used in healthy individuals as a marker of insulin resistance.
J. Alizargar, C. Bai, N. Hsieh, S. Wu
semanticscholar   +1 more source

Triglyceride [PDF]

open access: yesCirculation, 1998
The relation of serum TG concentrations and risk for CHD has been an issue of great interest and controversy. Unlike analyses with LDL-C and HDL-C, for which very strong and consistent relations with CHD risk have been demonstrated in observational and interventional studies, those with TG are ambiguous. Thus, TG represents a clinical conundrum: should
openaire   +1 more source

Association of Triglyceride-Lowering LPL Variants and LDL-C–Lowering LDLR Variants With Risk of Coronary Heart Disease

open access: yesJournal of the American Medical Association (JAMA), 2019
Importance Triglycerides and cholesterol are both carried in plasma by apolipoprotein B (ApoB)–containing lipoprotein particles. It is unknown whether lowering plasma triglyceride levels reduces the risk of cardiovascular events to the same extent as ...
B. Ference   +15 more
semanticscholar   +1 more source

The Long Term Kinetic of Plasma Lipids and Lipoproteins in Tyloxapol Injected Rats [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: The level of plasma triglyceride is balanced by the rate of secretion into and clearance from the plasma. Tyloxapol (Triton WR1339) is a nonionic detergent that inhibits lipoprotein lipase and hence clearance of triglyceride from the ...
Mehdi Rasouli   +2 more
doaj   +1 more source

Plasma metabolites reflect seasonally changing metabolic processes in a long-distance migrant shorebird (Calidris canutus) [PDF]

open access: yes, 2002
Migrant birds have tightly scheduled annual cycles consisting of several distinct life cycle (sub-)stages such as reproduction, migration, moult and overwintering, each of which have specific metabolic requirements (e.g., fattening during migration ...
Jenni, Lukas,   +2 more
core   +2 more sources

Remnants of the Triglyceride-Rich Lipoproteins, Diabetes, and Cardiovascular Disease

open access: yesDiabetes, 2020
Diabetes is now a pandemic disease. Moreover, a large number of people with prediabetes are at risk for developing frank diabetes worldwide. Both type 1 and type 2 diabetes increase the risk of atherosclerotic cardiovascular disease (CVD).
A. Chait   +5 more
semanticscholar   +1 more source

Structural and functional consequences of missense mutations in exon 5 of the lipoprotein lipase gene

open access: yesJournal of Lipid Research, 2002
Missense mutations in exon 5 of the LPL gene are the most common reported cause of LPL deficiency. Exon 5 is also the region with the strongest homology to pancreatic and hepatic lipase, and is conserved in LPL from different species. Mutant LPL proteins
Jonas Peterson   +8 more
doaj   +1 more source

Triglyceride Metabolism in the Liver.

open access: yesComprehensive Physiology, 2017
Triglyceride molecules represent the major form of storage and transport of fatty acids within cells and in the plasma. The liver is the central organ for fatty acid metabolism.
M. Alves‐Bezerra, D. Cohen
semanticscholar   +1 more source

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