Results 331 to 340 of about 821,330 (390)

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

open access: yesBMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah   +9 more
wiley   +1 more source

ARNT2-driven transcriptional activation of STRA6 reprograms fatty acid metabolism to promote retroperitoneal liposarcoma progression. [PDF]

open access: yesJ Cancer Res Clin Oncol
Zhang J   +10 more
europepmc   +1 more source

Intranuclear paraspeckle‐circular RNA TACC3 assembly forms RNA‐DNA hybrids to facilitate MASH‐related hepatocellular carcinoma growth in an m6A‐dependent manner

open access: yesCancer Communications, EarlyView.
Abstract Background Metabolic dysfunction‐associated steatohepatitis (MASH) is anticipated to become the leading cause of hepatocellular carcinoma (HCC). Accumulating evidence indicates that N6‐methyladenosine (m6A)‐modified circular RNAs (circRNAs) play key roles in tumor malignant progression.
Jingbo Fu   +22 more
wiley   +1 more source

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

open access: yesChemistry &Biodiversity, EarlyView.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida   +8 more
wiley   +1 more source

Larvicidal Activity of Phytochemicals From Handroanthus impetiginosus Seeds Against Culex quinquefasciatus

open access: yesChemistry &Biodiversity, EarlyView.
The hexane extract was obtained from the seeds of H. impetiginosus, from which fatty acids and FAMEs were obtained. The three samples were tested on C. quinquefasciatus larvae, promoting mortality with moderate LC50 values. The hexane extract was analyzed by gas chromatographymass spectrometry (GC‐MS), and the most abundant compounds were ethyl oleate (
Luana Cristina Diniz Santos   +6 more
wiley   +1 more source

Co‐cultivation and Medium Optimization: A Strategy for Discovering Fungal‐derived Protease Inhibitors

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The fungi Fusarium guttiforme and Phytophthora palmivora were cultivated in four different media (Potato Dextrose Agar, Czapek, rice, and ISP2) and co‐cultured to stimulate fungal interactions and enhance secondary metabolite production. Promising extracts were fractionated, yielding compounds such as the iron complex of fusaric acid (1 ...
Vitor de Souza Mazucato   +7 more
wiley   +1 more source

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