Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah +9 more
wiley +1 more source
ARNT2-driven transcriptional activation of STRA6 reprograms fatty acid metabolism to promote retroperitoneal liposarcoma progression. [PDF]
Zhang J +10 more
europepmc +1 more source
Abstract Background Metabolic dysfunction‐associated steatohepatitis (MASH) is anticipated to become the leading cause of hepatocellular carcinoma (HCC). Accumulating evidence indicates that N6‐methyladenosine (m6A)‐modified circular RNAs (circRNAs) play key roles in tumor malignant progression.
Jingbo Fu +22 more
wiley +1 more source
Association between the triglyceride-glucose index and brachial artery flow-mediated dilation function in non-diabetic patients receiving maintenance hemodialysis. [PDF]
Xu L +7 more
europepmc +1 more source
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida +8 more
wiley +1 more source
Exploring the association between triglyceride glucose index-related obesity indices and asthma-COPD overlap: NHANES 2001 to 2018. [PDF]
Qu H, Xie Q, Yang Y, Shao Y, Li C.
europepmc +1 more source
The hexane extract was obtained from the seeds of H. impetiginosus, from which fatty acids and FAMEs were obtained. The three samples were tested on C. quinquefasciatus larvae, promoting mortality with moderate LC50 values. The hexane extract was analyzed by gas chromatographymass spectrometry (GC‐MS), and the most abundant compounds were ethyl oleate (
Luana Cristina Diniz Santos +6 more
wiley +1 more source
The combined prognostic effect of the triglyceride-glucose index and estimated glucose disposal rate on long-term mortality among individuals with cardiovascular-kidney-metabolic syndrome stages 0-3. [PDF]
Wang K +9 more
europepmc +1 more source
Circulating markers of arterial thrombosis and age-related maculopathy: a case-control study [PDF]
MacCallum, PK +3 more
core
ABSTRACT The fungi Fusarium guttiforme and Phytophthora palmivora were cultivated in four different media (Potato Dextrose Agar, Czapek, rice, and ISP2) and co‐cultured to stimulate fungal interactions and enhance secondary metabolite production. Promising extracts were fractionated, yielding compounds such as the iron complex of fusaric acid (1 ...
Vitor de Souza Mazucato +7 more
wiley +1 more source

