Results 101 to 110 of about 457,139 (259)

Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes

open access: yesJournal of Lipid Research, 2002
Recent studies on the in vivo roles of the sterol regulatory element binding protein (SREBP) family indicate that SREBP-2 is more specific to cholesterogenic gene expression whereas SREBP-1 targets lipogenic genes.
Michiyo Amemiya-Kudo   +16 more
doaj  

Function and dysfunction of fatty acid mobilization: a review [PDF]

open access: yes, 2018
Western populations have a growing obesity epidemic due in part to excessive nutrient intake from high-fat diets, which are increasingly common. Overindulgence of nutrients is associated with a greater incidence of metabolic dysfunction and a greater ...
Beard, Joslyn K.   +2 more
core   +1 more source

Increased atherosclerosis in diabetic dyslipidemic swine

open access: yesJournal of Lipid Research, 2002
Male Yucatan swine were allocated to four groups (n = 5–6 pigs per group): low fat (3%) fed control, high fat/2% cholesterol (CH) fed (HF), high fat/CH fed with alloxan-induced diabetes (DF) and DF pigs that were treated with atorvastatin (80 mg/day; DF ...
Joseph L. Dixon   +5 more
doaj  

Accurate quantification of lipid species affected by isobaric overlap in Fourier-transform mass spectrometry

open access: yesJournal of Lipid Research, 2021
: Lipidomics data require consideration of ions with near-identical masses, which comprises among others the Type-II isotopic overlap. This overlap occurs in series of lipid species differing only by number of double bonds (DBs) mainly because of the ...
Marcus Höring   +5 more
doaj  

Prevention of cardiovascular disease based on lipid lowering treatment: a challenge for the Mexican health system Prevención de la enfermedad cardiovascular basada en tratamiento hipolipemiante: un reto para el sistema de salud de México

open access: yesSalud Pública de México, 2010
OBJECTIVE: To estimate the percentage of Mexican adults that may require lipid-lowering treatment according to National Cholesterol Education Program-III guidelines, using data from the National Health and Nutrition Survey 2006 (ENSANut 2006).
Francisco J Gómez-Pérez   +5 more
doaj  

Stereospecific analysis of triglycerides: an alternative method

open access: yesJournal of Lipid Research, 1967
A new method for the stereospecific analysis of triglycerides is demonstrated on a corn oil which had been analyzed by an earlier method. The triglyceride (1,2,3-triacyl l-glycerol) was partially degraded by means of methyl magnesium bromide.
H. Brockerhoff
doaj  

Secondary Phenotype Analysis in Ascertained Family Designs: Application to the Leiden Longevity Study [PDF]

open access: yesarXiv, 2016
The case-control design is often used to test associations between the case-control status and genetic variants. In addition to this primary phenotype a number of additional traits, known as secondary phenotypes, are routinely recorded and typically associations between genetic factors and these secondary traits are studied too.
arxiv  

Enhancing Metabolic Syndrome Prediction with Hybrid Data Balancing and Counterfactuals [PDF]

open access: yesarXiv
Metabolic Syndrome (MetS) is a cluster of interrelated risk factors that significantly increases the risk of cardiovascular diseases and type 2 diabetes. Despite its global prevalence, accurate prediction of MetS remains challenging due to issues such as class imbalance, data scarcity, and methodological inconsistencies in existing studies.
arxiv  

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