Results 121 to 130 of about 487,969 (369)

An Apolipoprotein Influencing Triglycerides in Humans and Mice Revealed by Comparative Sequencing

Science, 2001
Comparison of genomic DNA sequences from human and mouse revealed a new apolipoprotein (APO) gene (APOAV) located proximal to the well-characterized APOAI/CIII/AIV gene cluster on human 11q23.
L. Pennacchio, M. Olivier, J. Hubacek, Jonathan C. Cohen, D. Cox, J. Fruchart, R. Krauss, E. Rubin   +7 more
semanticscholar   +1 more source

Triglycerides and disease [PDF]

Postgraduate Medical Journal, 1993
C. A. Seymour, Christopher D. Byrne
openaire   +2 more sources

Asprosin‐FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development

Advanced Science, EarlyView.
Aided by FABP5, abnormally elevated asprosin in hepatocytes enters the nucleus, targets and inhibits PPARα binding to the CPT1A promoter, thereby suppressing FAO. Circulating asprosin exacerbates insulin resistance, collectively driving MASLD progression.
Yuan‐Yuan Yu, Min Feng, Yi Chen, Hong‐Lin Jia, Qi Zhang, Ming Tong, Yan‐Xi Li, Yu Zhao, Xin‐Xin Liu, Shi‐Feng Cao, Zheng‐kai Wang, Hou‐wei Li, Xue Liu, Yan Zhang   +13 more
wiley   +1 more source

Predictors and morphological properties of culprit healed plaques in patients with angina pectoris

Clinical Cardiology, Volume 45, Issue 12, Page 1199-1210, December 2022., 2022
Abstract Background Plaque healing may serve a vital function in the natural progression of atherosclerotic disease. This study sought to investigate predictors and morphological characteristics of healed plaque (HP) among angina pectoris (AP) patients.
Hongying Yao, Qianyun Guo, Yujing Cheng, Tianyu Zhu, Qian Ma, Yujie Zhou   +5 more
wiley   +1 more source

ANGPTL4 silencing via antisense oligonucleotides reduces plasma triglycerides and glucose in mice without causing lymphadenopathy

Journal of Lipid Research, 2022
Angiopoietin-like 4 (ANGPTL4) is an important regulator of plasma triglyceride (TG) levels and an attractive pharmacological target for lowering plasma lipids and reducing cardiovascular risk.
Mingjuan Deng, Elda Kutrolli, Anne Sadewasser, Sven Michel, Masoumeh Motamedi Joibari, Frank Jaschinski, Gunilla Olivecrona, Stefan K. Nilsson, Sander Kersten   +8 more
doaj  

Paternal Obesity‐Induced H3K27me3 Elevation Leads to MANF‐Mediated Transgenerational Metabolic Dysfunction in Female Offspring

Advanced Science, EarlyView.
Paternal lifestyle and environmental exposures play a critical role in the offspring's health. The present study established a paternal obesity model and demonstrated that elevated H3K27me3 levels in sperm persist through the 8‐cell embryo stage. This epigenetic modification triggers transgenerational decrease of MANF, inducing ER stress and activating
Yajun Shi, Weisheng Li, Xi Yu, Yan Zhao, Dan Zhu, Yueyang Song, Zejun Zhao, Yannan Gu, Bin Wei, Lingjun Li, Dongyi Yu, Pengjie Zhang, Qinqin Gao, Miao Sun   +13 more
wiley   +1 more source

Day‐to‐day fasting plasma glucose variability on the short‐term prognosis of ST‐segment elevation myocardial infarction: A retrospective cohort study

Clinical Cardiology, Volume 45, Issue 12, Page 1246-1254, December 2022., 2022
Abstract Background and Hypothesis Glycemic variability in one fact that explain the differences in cardiovascular outcomes. The short‐term fasting plasma glucose (FPG) variability may have an on major adverse cardiovascular events (MACE) in type 2 diabetes mellitus (T2DM) patients with ST‐segment elevation myocardial infarction (STEMI).
Ming Yi, Qing Cao, Wen‐hui Tang, Qiang Liu, Xiao Ke   +4 more
wiley   +1 more source

Ueber die Zersetzung der Triglyceride durch verdünnte Säuren [PDF]

, 1898
A. C. Geitel
openalex   +1 more source

Triglycerides and Residual Atherosclerotic Risk

Journal of the American College of Cardiology, 2021
S. Raposeiras-Roubín, X. Rosselló, B. Oliva, L. Fernández-Friera, J. Mendiguren, V. Andrés, Héctor Bueno, J. Sanz, Vicente Martínez de Vega, E. Abu-Assi, A. Íñiguez, A. Fernández-Ortiz, B. Ibáñez, V. Fuster   +13 more
semanticscholar   +1 more source

Antisense Oligonucleotide Inhibition of Apolipoprotein C-III Reduces Plasma Triglycerides in Rodents, Nonhuman Primates, and Humans

Circulation Research, 2013
Rationale: Elevated plasma triglyceride levels have been recognized as a risk factor for the development of coronary heart disease. Apolipoprotein C-III (apoC-III) represents both an independent risk factor and a key regulatory factor of plasma ...
M. Graham, Richard G. Lee, T. Bell, W. Fu, A. Mullick, V. Alexander, W. Singleton, N. Viney, R. Geary, John Su, B. Baker, J. Burkey, S. Crooke, R. Crooke   +13 more
semanticscholar   +1 more source