Results 131 to 140 of about 699,051 (382)

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

Alterations of lipid metabolism in Wilson disease

Lipids in Health and Disease, 2011
Introduction Wilson disease (WD) is an inherited disorder of human copper metabolism, characterised by accumulation of copper predominantly in the liver and brain, leading to severe hepatic and neurological disease.
Stremmel Wolfgang, Eckert Nicola, Pfeiffenberger Jan, Gotthardt Daniel, Gohdes Annina, Seessle Jessica, Reuner Ulrike, Weiss Karl   +7 more
doaj   +1 more source

Central obesity as a precursor to the metabolic syndrome in the AusDiab study and Mauritius

, 2008
Evidence from epidemiologic studies that central obesity precedes future metabolic change and does not occur concurrently with the appearance of the blood pressure, glucose, and lipid abnormalities that characterize the metabolic syndrome (MetS) has been
Adrian J. Cameron, Alberti, Alessi, Barr, Boyko, Cameron, Carr, Chuang, Dowse, Dunstan, Edward J. Boyko, Franks, Fukuhara, Gus, Hillier, Hu, Jaakko Tuomilehto, Jonathan E. Shaw, K. George M.M. Alberti, Knowler, Liese, Maison, Manley, Matsuzawa, Miller, Odeleye, Palaniappan, Pan, Paul Z. Zimmet, Pierrot Chitson, Ratner, Richard A. Sicree, Shen, Shoelson, Snijder, Srinivasan, Stefan Söderberg, Söderberg, Söderberg, Söderberg, Söderberg, Tuomilehto, Uysal, Vickers, Wallace, Wang, Williams, World Health Organization   +47 more
core   +1 more source

Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction.

European Heart Journal, 2013
AIMS Elevated non-fasting triglycerides mark elevated levels of remnant cholesterol. Using a Mendelian randomization approach, we tested whether genetically increased remnant cholesterol in hypertriglyceridaemia due to genetic variation in the ...
A. Jørgensen, R. Frikke-Schmidt, A. West, P. Grande, B. Nordestgaard, A. Tybjærg‐Hansen   +5 more
semanticscholar   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

Advanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu   +9 more
wiley   +1 more source

Ueber die Zersetzung der Triglyceride durch verdünnte Säuren [PDF]

, 1898
A. C. Geitel
openalex   +1 more source

Lactate‐Activated GPR132‐Src Signal Induces Macrophage Senescence and Aggravates Atherosclerosis Under Diabetes

Advanced Science, EarlyView.
Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge, Shuying Wang, Zhaokai Li, Jing Yu, Binbin Liu, Ruiying Wang, Shichen Bu, Nawsher wan, Yan Wang, Cuilian Dai, Yijun Lin   +10 more
wiley   +1 more source

Zur Kenntnis der Glycerinester der Benzoe‐ und Myristinsäure und über partielle Verseifung der Triglyceride [PDF]

, 1913
A. Lipp, P. Miller
openalex   +1 more source

Low nonfasting triglycerides and reduced all-cause mortality: a mendelian randomization study.

Clinical Chemistry, 2014
BACKGROUND Increased nonfasting plasma triglycerides marking increased amounts of cholesterol in remnant lipoproteins are important risk factors for cardiovascular disease, but whether lifelong reduced concentrations of triglycerides on a genetic basis ...
M. Thomsen, A. Varbo, A. Tybjærg‐Hansen, B. Nordestgaard   +3 more
semanticscholar   +1 more source

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

Advanced Science, EarlyView.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang   +11 more
wiley   +1 more source