Results 131 to 140 of about 487,969 (369)

Decoding Blastocystis‐Driven Mechanisms in Gut Microbiota and Host Metabolism

open access: yesAdvanced Science, EarlyView.
Blastocystis, a prevalent gut microbe, interacts with the host through metabolic and immune pathways, influencing cardiometabolic health. This perspective explores its role in modulating short‐chain fatty acid production, tryptophan metabolism, and immune signaling, potentially impacting cholesterol absorption, glucose metabolism, and vascular health ...
Lei Deng, Kevin SW Tan
wiley   +1 more source

Predictive value of HMGB1 for atrial fibrillation recurrence after cryoballoon ablation in paroxysmal atrial fibrillation patients

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1229-1235, December 2022., 2022
Abstract Background Cryoballoon ablation (CBA) is recommended for patients with symptomatic drug refractory paroxysmal atrial fibrillation (pAF). However, substantial atrial fibrillation (AF) recurrence is common during follow‐up. Searching for a potential biomarker representing both myocardial injury and inflammation to identify patients at high risk ...
Xinxin Li   +9 more
wiley   +1 more source

Evaluation of metabolic profile and C‐reactive protein concentrations in brachycephalic dogs with upper airway obstructive syndrome

open access: yesJournal of Veterinary Internal Medicine, 2019
Background Brachycephalic dogs have abnormal breathing patterns similar to those in humans with obstructive sleep apnea syndrome. Obstructive sleep apnea syndrome is associated with dyslipidemia, hyperglycemia, and insulin resistance.
Paola Gianella   +8 more
doaj   +1 more source

Metformin Lowers Plasma Triglycerides by Promoting VLDL-Triglyceride Clearance by Brown Adipose Tissue in Mice

open access: yesDiabetes, 2014
Metformin is the first-line drug for the treatment of type 2 diabetes. Besides its well-characterized antihyperglycemic properties, metformin also lowers plasma VLDL triglyceride (TG).
J. Geerling   +9 more
semanticscholar   +1 more source

ISG15 Enhances the Activity of γ‐Glutamate Cysteine Ligase to Suppress Apoptosis in High Fat Diet‐Promoted Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Hepatocellular carcinoma (HCC) cells under high‐fat environment constrain harmful reactive oxygen species (ROS) by enhancing glutathione synthesis though upregulating interferon stimulated gene 15 (ISG15). In this process, upregulated high mobility group A1 (HMGA1) enhances ISG15 transcription, upregulated ISG15 subsequently noncovalently binds with ...
Xinran Liu   +21 more
wiley   +1 more source

Association between serum cystatin C and early impairment of cardiac function and structure in type 2 diabetes patients with normal renal function

open access: yesClinical Cardiology, Volume 45, Issue 12, Page 1287-1296, December 2022., 2022
Abstract Background Type 2 diabetes mellitus (T2DM) patients may have cardiac remodeling and dysfunction from the early stage of disease. This study aimed to determine the association between cystatin C (CysC) and early cardiac functional or structural impairment in T2DM patients without renal dysfunction.
Zhuoshan Huang   +10 more
wiley   +1 more source

Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes

open access: yesJournal of Lipid Research, 2002
Recent studies on the in vivo roles of the sterol regulatory element binding protein (SREBP) family indicate that SREBP-2 is more specific to cholesterogenic gene expression whereas SREBP-1 targets lipogenic genes.
Michiyo Amemiya-Kudo   +16 more
doaj  

Added sugars in the diet are positively associated with diastolic blood pressure and triglycerides in children.

open access: yesAmerican Journal of Clinical Nutrition, 2014
BACKGROUND Hypertension and dyslipidemia have traditionally been associated with dietary sodium and fat intakes, respectively; however, they have recently been associated with the consumption of added sugars in adults and older adolescents, but there is ...
K. Kell   +3 more
semanticscholar   +1 more source

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