Results 181 to 190 of about 725,613 (387)

Genetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study. [PDF]

, 2017
Results from observational studies examining dyslipidemia as a risk factor for diabetic retinopathy (DR) have been inconsistent. We evaluated the causal relationship between plasma lipids and DR using a Mendelian randomization approach.
Asian Genetic Epidemiology Network Consortium, Burdon, Kathryn P, Chen, Ching J, Chen, Yii-Der Ida, Cheng, Ching-Yu, Chong, Yong He, Christiansen, Mark W, Cotch, Mary Frances, Craig, Jamie E, Fan, Qiao, Gan, Alfred, Gudnason, Vilmundur, Guo, Xiuqing, Hai, Yang, Hancock, Heather, Hanis, Craig L, Huang, Yu-Chuen, Hung, Yi-Jen, Ipp, Eli, Jensen, Richard A, Jia, Yucheng, Kaidonis, Georgia, Kim, Jihye, Klein, Barbara EK, Klein, Ronald, Kuo, Jane, Lee, Wen-Jane, Li, Xiaohui, Liao, Wen-Ling, Liew, Gerald, Mitchell, Paul, Penman, Alan, Pollack, Samuela, Price, Alkes, Psaty, Bruce M, Rotter, Jerome I, Sandow, Kevin, Smith, Albert V, Sobrin, Lucia, Stanwyck, Lynn K, Tan, Gavin, Tsai, Fuu-Jen, Wang, Jie Jin, Wong, Tien Yin   +43 more
core   +1 more source

Triglyceride Utilization by Human HeLa and Conjunctiva Cells in Tissue Culture

, 1959
Robert P. Geyer, JOYCE M. NEIMARK
openalex   +1 more source

Calcium absorption in the normal, bile-duct ligated, and cirrhotic rat, with observations on the effect of long- and medium-chain triglycerides. [PDF]

, 1968
A K Kehayoglou, H S Williams, W F Whimster, C D Holdsworth   +3 more
openalex   +1 more source

Deficiency of Leucine‐Rich Repeat Containing G Protein‐Coupled Receptor 4 in Pancreas Reduces β Cell Mass

Advanced Science, EarlyView.
In islet β cells, LGR4 binds with Rspondin to activate the Wnt‐β‐catenin‐Ccnd1 axis, leading to a subsequent increase in cell proliferation. On the other hand, LGR4 also binds with RANKL, thus suppressing the phosphorylation of p44/p42 MAPK and p65 NF‐κB and subsequent cell apoptosis.
Chao Luo, Yifan Feng, Jiajie Min, Yan Zhao, Ziming Zhu, Lijun Sun, Hao Yin, Yue Yin, Weizhen Zhang   +8 more
wiley   +1 more source

ROUTE OF ABSORPTION OF FREE FATTY ACIDS AND TRIGLYCERIDES FROM THE INTESTINE

, 1951
Raymond Reiser, Melvin J. Bryson
openalex   +1 more source

Nonalcoholic Fatty Liver Disease Exacerbates the Advancement of Renal Fibrosis by Modulating Renal CCR2+PIRB+ Macrophages Through the ANGPTL8/PIRB/ALOX5AP Axis

Advanced Science, EarlyView.
The ANGPTL8/PIRB/ALOX5AP axis mediates liver‐kidney crosstalk. Hepatocytes secrete ANGPTL8, which binds to CCR2+PIRB+ macrophages in the kidneys, affecting the expression of ALOX5AP and enhancing the activation of these macrophages. Activated cells produce TGF‐β, IL‐6, and IL‐23, driving Th17 activation and promote the formation of myofibroblasts ...
Shuqi Wei, Diwen Shou, Siyuan Huang, Yingsi Wang, Quanzhen Liu, Jinfa Liu, Xiaoyu Lv, Yuyi Zeng, Liting Wei, Han Lin, Jiechuan Chen, Yangxiao Chen, Haoyu Zhong, Yanqing Zhou, Wen Ma, Li Wang, Guojun Qian, Jing Guo, Donglin Sun   +18 more
wiley   +1 more source

Polarization‐Sensitive Holotomography for Multidimensional Label‐Free Imaging and Characterization of Lipid Droplets in Cancer Cells

Advanced Science, EarlyView.
Polarization‐sensitive holotomography (PS‐HT) enables label‐free 3D imaging and quantitative analysis of lipid droplets by exploiting their intrinsic birefringence. Applied to prostate cell models, PS‐HT reveals glucose‐induced lipid accumulation in cancer cells and achieves near‐perfect classification of healthy and cancerous states.
Hossein Khadem, Maria Mangini, Maria Antonietta Ferrara, Anna Chiara De Luca, Giuseppe Coppola   +4 more
wiley   +1 more source

Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women.

Journal of the American Medical Association (JAMA), 2007
B. Nordestgaard, M. Benn, P. Schnohr, A. Tybjaerg-hansen   +3 more
semanticscholar   +1 more source

NRF2‐REGγ‐ACADM/KLF15 Signaling Pathway Regulates the Browning of White Adipose Tissue to Modulate Obesity

Advanced Science, EarlyView.
This study identifies that REGγ is elevated in obese adipose tissue. REGγ modulates WAT browning via ubiquitin‐independent ACADM/KLF15–UCP1 degradation. Overactivation of the NRF2–REGγ axis facilitates adipose tissue function to cause obesity. Inhibition of REGγ in the iWAT alleviates HFD‐induced obesity.
Hui Chen, Qiujing Guan, Shuangming Gong, Yingying Du, Zhidan Zhang, Yan Liu, Lei Zhou, Lin Liu, Baoquan Xin, Yilan Guo, Hui Zhang, Ziyang Zhou, Tongchao Pei, Guohong Yu, Sokun Yin, Lei Li   +15 more
wiley   +1 more source

Triglycerides and cardiovascular disease: a scientific statement from the American Heart Association.

Circulation, 2011
Michael Miller, N. Stone, C. Ballantyne, V. Bittner, M. Criqui, H. Ginsberg, A. Goldberg, W. Howard, M. Jacobson, P. Kris-Etherton, T. Lennie, M. Levi, T. Mazzone, S. Pennathur   +13 more
semanticscholar   +1 more source