Results 51 to 60 of about 699,051 (382)

Effect of Vascepa (icosapent ethyl) on progression of coronary atherosclerosis in patients with elevated triglycerides (200-499 mg/dL) on statin therapy: Rationale and design of the EVAPORATE study. [PDF]

, 2018
Despite reducing progression and promoting regression of coronary atherosclerosis, statin therapy does not fully address residual cardiovascular (CV) risk.
Brent Muhlestein, J, Budoff, Matthew, Le, Viet T, May, Heidi T, Nelson, John R, Roy, Sion   +5 more
core   +2 more sources

The triglyceride lipases of the pancreas [PDF]

Journal of Lipid Research, 2002
Pancreatic triglyceride lipase (PTL) and its protein cofactor, colipase, are required for efficient dietary triglyceride digestion. In addition to PTL, pancreatic acinar cells synthesize two pancreatic lipase related proteins (PLRP1 and PLRP2), which have a high degree of sequence and structural homology with PTL. PLRP1 has no known activity.
openaire   +4 more sources

ANTIDIABETIC EFFECT EVALUATION AND CHARACTERIZATION OF BIOACTIVE COMPOUNDS ISOLATED FROM HYDROLEA ZEYLANICA

Indonesian Journal of Pharmacy, 2015
The whole plant of Hydrolea zeylanica (HZ) (Hydrophyllaceae family) was coarsely powdered and extracted with ethanol using soxhlet apparatus. The ethanol extract was then fractionated successively using various polarity ranges of solvents and screened ...
Borkar Vijay S, Senthil Kumaran K,, Senthil Kumar KL, Gangurde Hemant H, Chordiya Mayur A   +4 more
doaj   +1 more source

Hypolipidemic effect of aqueous extract from the leaves of Artocarpus altilis "breadfruit" in Rattus norvegicus induced hyperlipidemia

Scientia Agropecuaria, 2013
The present study aimed to demonstrate the hypolipidemic activity of aqueous extract of leaves of breadfruit, Artocarpus altilis, in a model of acute hyperlipidemia induced with triton X-305, using Rattus norvegicus specimens males, mean weight 204.5 g ...
Julio Campos Florián
doaj   +1 more source

Data on the effects of low iron diet on serum lipid profile in HCV transgenic mouse model [PDF]

, 2017
Here, we presented new original data on the effects of iron depletion on the circulating lipid pro fi le in B6HCV mice, a murine model of HCV-related dyslipidemia. Male adult B6HCV mice were subjected to non-invasive iron depletion by low iron diet.
Amato, Rosario, Conigliaro, Alice, Costa, Viviana, Mancone, Carmine   +3 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Incidence of pancreatitis, secondary causes, and treatment of patients referred to a specialty lipid clinic with severe hypertriglyceridemia: a retrospective cohort study

Lipids in Health and Disease, 2011
Background Severe hypertriglyceridemia (HTG) is one cause of acute pancreatitis, yet the level of plasma triglycerides likely to be responsible for inducing pancreatitis has not been clearly defined.
Francis Gordon A, Frohlich Jiri, Taraboanta Catalin, Al-Sarraf Ahmad, Sandhu Supna   +4 more
doaj   +1 more source

TRIGLYCERIDES | Liquid Chromatography

, 2000
Peer ...
Ruiz-Gutiérrez, Valentina, Perona, Javier S.   +1 more
openaire   +3 more sources

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Changes in lipids over twelve months after initiating protease inhibitor therapy among persons treated for HIV/AIDS

Lipids in Health and Disease, 2005
Background Protease inhibitors are known to alter the lipid profiles in subjects treated for HIV/AIDS. However, the magnitude of this effect on plasma lipoproteins and lipids has not been adequately quantified. Objective To estimate the changes in plasma
Hogg Robert S, Harrigan P Richard, McCandless Lawrence, Levy Adrian R, Bondy Greg, Iloeje Uchenna H, Mukherjee Jayanti, Montaner Julio S   +7 more
doaj   +1 more source