Results 61 to 70 of about 512,588 (331)

Statistical Analysis of Lipid Profiles Associated with Coronary Heart Disease in Erbil City-Iraq

Polytechnic Journal, 2023
Background and objectives: Coronary heart disease (CHD) is one of the most prevalent diseases worldwide. The primary risk factor for coronary heart disease (CHD) lies in the presence of hypertension, elevated levels of triglycerides (TG), total ...
Dler Hussein Kadir, Karzan Abdullah, Aziz Muazafar Jafaar, Rebaz Hamza Salih, Shukur Wasman Smail, Gashaw Qasim Rahman, Harem Khdir Awla, Zhikal Omar Khudhur   +7 more
doaj   +1 more source

GALNT2 as a novel modulator of adipogenesis and adipocyte insulin signaling [PDF]

, 2019
Background/objectives: A better understanding of adipose tissue biology is crucial to tackle insulin resistance and eventually coronary heart disease and diabetes, leading causes of morbidity and mortality worldwide.
Antonucci, A., De Bonis, Maria Caterina, Di Paola, R., Mangiacotti, D., Marucci, A., Scarale, M. G., Trischitta, V.   +6 more
core   +1 more source

Serum Uric Acid Levels in Older Adults: Associations With Clinical Outcomes and Implications for Reference Intervals in Those Aged 70 Years and Over

Arthritis Care &Research, EarlyView.
Objective Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged ≥70 years old.
Amanda J. Rickard, Cammie Tran, Hans G. Schneider, Flavia M. Cicuttini, Anita E. Wluka, Ego Seeman, Johannes T. Neumann, Md Nazmul Karim, Zhen Zhou, Sultana Monira Hussain, David P. Q. Clark, Daniel Clayton‐Chubb, Andrew M. Tonkin, Lawrence J. Beilin, Robyn L. Woods, John J. McNeil   +15 more
wiley   +1 more source

Elevated Triglycerides (≥150 mg/dL) and High Triglycerides (200–499 mg/dL) Are Significant Predictors of New Heart Failure Diagnosis: A Real-World Analysis of High-Risk Statin-Treated Patients

Vascular Health and Risk Management, 2019
Peter P Toth,1,2 Sephy Philip,3 Michael Hull,4 Craig Granowitz3 1CGH Medical Center, Sterling, IL, USA; 2Johns Hopkins University School of Medicine, Baltimore, MD, USA; 3Amarin Pharma Inc, Bedminster, NJ, USA; 4Optum, Eden Prairie, MN, USACorrespondence:
Toth PP, Philip S, Hull M, Granowitz C
doaj  

Improved lipid profile through liver-specific knockdown of liver X receptor α in KKAy diabetic mice

Journal of Lipid Research, 2009
Nuclear hormone receptors liver X receptor (LXRα and LXRβ) ligands are attractive approaches for the treatment of dyslipidemia and atherosclerosis. To further elucidate the function of LXRα in liver lipid metabolism in a disease-relevant animal model ...
Joerg F. Rippmann, Corinna Schoelch, Thomas Nolte, Heidi Pavliska, André van Marle, Helmuth van Es, Juergen Prestle   +6 more
doaj   +1 more source

Incidence of components of metabolic syndrome in the metabolically healthy obese over 9 years follow-up: the Atherosclerosis Risk In Communities study. [PDF]

, 2017
BackgroundSome obese adults are not afflicted by the metabolic abnormalities often associated with obesity (the 'metabolically healthy obese' (MHO)); however, they may be at increased risk of developing cardiometabolic abnormalities in the future. Little
Bradshaw, PT, Ndumele, CE, Reynolds, KR, Stevens, J, Wagenknecht, LE   +4 more
core   +2 more sources

Adipokines and Associations With Incident Osteoporotic Fracture in Patients With Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective We assessed whether circulating adipokines are associated with incident fractures in patients with rheumatoid arthritis (RA). Methods Three adipokines (adiponectin, leptin, and fibroblast growth factor [FGF]‐21) were measured using banked enrollment serum from participants in a longitudinal RA cohort.
Joshua F. Baker, Bryant R. England, Michael D. George, Hannah Brubeck, Brian Sauer, Aleksander Lenert, Punyasha Roul, Geoffrey M. Thiele, Ted R. Mikuls, Katherine D. Wysham   +9 more
wiley   +1 more source

The Alcohol–High-Density Lipoprotein Athero-Protective Axis

Biomolecules, 2020
Ingestion of alcohol is associated with numerous changes in human energy metabolism, especially that of plasma lipids and lipoproteins. Regular moderate alcohol consumption is associated with reduced atherosclerotic cardiovascular disease (ASCVD), an ...
Corina Rosales, Baiba K. Gillard, Antonio M. Gotto, Henry J. Pownall   +3 more
doaj   +1 more source

Sex differences in the associations between birthweight and lipid levels in middle-age: findings from the 1958 British birth cohort [PDF]

, 2008
Objective To examine sex differences in birthweight–lipid associations. Methods and results Using prospectively collected data on birthweight and non-fasting lipid levels at age 44–45 y from the 1958 British birth cohort (3603 men and 3583 women ...
Cooper, R., Power, C.
core  

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

Arthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source