Results 81 to 90 of about 457,139 (259)

Prevalence and Pattern of Dyslipidemia and Its Associated Factors Among Patients with Type 2 Diabetes Mellitus in Jordan: A Cross-Sectional Study

open access: yesInternational Journal of General Medicine, 2022
Thekraiat M Al Quran,1 Ziad A Bataineh,2 Abdel-Hameed Al-Mistarehi,1 Anas M Zein Alaabdin,1 Hadeel Allan,1 Anood Al Qura’an,3 Shatha M Weshah,1 Anfal A Alanazi,4 Yousef S Khader1 1Department of Public Health and Family Medicine, Faculty of Medicine ...
Al Quran TM   +8 more
doaj  

Genome analysis and pleiotropy assessment using causal networks with loss of function mutation and metabolomics [PDF]

open access: yesarXiv, 2019
Background: Many genome-wide association studies have detected genomic regions associated with traits, yet understanding the functional causes of association often remains elusive. Utilizing systems approaches and focusing on intermediate molecular phenotypes might facilitate biologic understanding.
arxiv  

A Bayesian method for estimating gene-level polygenicity under the framework of transcriptome-wide association study [PDF]

open access: yesarXiv, 2022
Polygnicity refers to the phenomenon that multiple genetic variants have a non-zero effect on a complex trait. It is defined as the proportion of genetic variants that have a nonzero effect on the trait. Evaluation of polygenicity can provide valuable insights into the genetic architecture of the trait.
arxiv  

The use of computers to study rates of lipid metabolism

open access: yesJournal of Lipid Research, 1969
Many complex problems of lipid metabolism are especially suited for multicompartmental analysis with computers. Examples are presented. The use of a model as a means of communicating one's working hypothesis and the model as it relates to experimental ...
Nome Baker
doaj  

Diferencias de sexo, edad y lípidos plasmáticos asociadas al polimorfismo de la apolipoproteína E en un grupo de escolares de Quindío, Colombia

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2009
Introducción. El polimorfismo de la apolipoproteína E (apoE) es un factor determinante genético de los niveles de colesterol total y colesterol LDL. Objetivo.
Nelsy Loango   +3 more
doaj   +1 more source

A Copula-based Fully Bayesian Nonparametric Evaluation of Cardiovascular Risk Markers in the Mexico City Diabetes Study [PDF]

open access: yesarXiv, 2020
Cardiovascular disease lead the cause of death world wide and several studies have been carried out to understand and explore cardiovascular risk markers in normoglycemic and diabetic populations. In this work, we explore the association structure between hyperglycemic markers and cardiovascular risk markers controlled by triglycerides, body mass index,
arxiv  

Pathogenetic mechanisms of the relationship between reproductive dysfunction in men with arterial hypertension and lipid metabolism

open access: yesИзвестия высших учебных заведений. Поволжский регион: Медицинские науки, 2022
Background. Male infertility refers to multifactorial diseases that have been studied quite deeply and the role of arterial hypertension and lipid metabolism in the mechanism of its development has not been studied at all.
L.V. Kurashvili   +4 more
doaj   +1 more source

Autophagy regulates sphingolipid levels in the liver[S]

open access: yesJournal of Lipid Research, 2014
Sphingolipid levels are tightly regulated to maintain cellular homeostasis. During pathologic conditions such as in aging, inflammation, and metabolic and neurodegenerative diseases, levels of some sphingolipids, including the bioactive metabolite ...
Aikaterini Alexaki   +7 more
doaj  

Multi-modal Predictive Models of Diabetes Progression [PDF]

open access: yes, 2019
With the increasing availability of wearable devices, continuous monitoring of individuals' physiological and behavioral patterns has become significantly more accessible. Access to these continuous patterns about individuals' statuses offers an unprecedented opportunity for studying complex diseases and health conditions such as type 2 diabetes (T2D).
arxiv   +1 more source

Serum TG-lowering properties of plant sterols and stanols are associated with decreased hepatic VLDL secretion[S]

open access: yesJournal of Lipid Research, 2014
Plant sterols and stanols are structurally similar to cholesterol and when added to the diet they are able to reduce serum total- and LDL-cholesterol concentrations.
Marleen Schonewille   +4 more
doaj  

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