Results 81 to 90 of about 457,139 (259)
Thekraiat M Al Quran,1 Ziad A Bataineh,2 Abdel-Hameed Al-Mistarehi,1 Anas M Zein Alaabdin,1 Hadeel Allan,1 Anood Al Qura’an,3 Shatha M Weshah,1 Anfal A Alanazi,4 Yousef S Khader1 1Department of Public Health and Family Medicine, Faculty of Medicine ...
Al Quran TM+8 more
doaj
Genome analysis and pleiotropy assessment using causal networks with loss of function mutation and metabolomics [PDF]
Background: Many genome-wide association studies have detected genomic regions associated with traits, yet understanding the functional causes of association often remains elusive. Utilizing systems approaches and focusing on intermediate molecular phenotypes might facilitate biologic understanding.
arxiv
A Bayesian method for estimating gene-level polygenicity under the framework of transcriptome-wide association study [PDF]
Polygnicity refers to the phenomenon that multiple genetic variants have a non-zero effect on a complex trait. It is defined as the proportion of genetic variants that have a nonzero effect on the trait. Evaluation of polygenicity can provide valuable insights into the genetic architecture of the trait.
arxiv
The use of computers to study rates of lipid metabolism
Many complex problems of lipid metabolism are especially suited for multicompartmental analysis with computers. Examples are presented. The use of a model as a means of communicating one's working hypothesis and the model as it relates to experimental ...
Nome Baker
doaj
Introducción. El polimorfismo de la apolipoproteína E (apoE) es un factor determinante genético de los niveles de colesterol total y colesterol LDL. Objetivo.
Nelsy Loango+3 more
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A Copula-based Fully Bayesian Nonparametric Evaluation of Cardiovascular Risk Markers in the Mexico City Diabetes Study [PDF]
Cardiovascular disease lead the cause of death world wide and several studies have been carried out to understand and explore cardiovascular risk markers in normoglycemic and diabetic populations. In this work, we explore the association structure between hyperglycemic markers and cardiovascular risk markers controlled by triglycerides, body mass index,
arxiv
Background. Male infertility refers to multifactorial diseases that have been studied quite deeply and the role of arterial hypertension and lipid metabolism in the mechanism of its development has not been studied at all.
L.V. Kurashvili+4 more
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Autophagy regulates sphingolipid levels in the liver[S]
Sphingolipid levels are tightly regulated to maintain cellular homeostasis. During pathologic conditions such as in aging, inflammation, and metabolic and neurodegenerative diseases, levels of some sphingolipids, including the bioactive metabolite ...
Aikaterini Alexaki+7 more
doaj
Multi-modal Predictive Models of Diabetes Progression [PDF]
With the increasing availability of wearable devices, continuous monitoring of individuals' physiological and behavioral patterns has become significantly more accessible. Access to these continuous patterns about individuals' statuses offers an unprecedented opportunity for studying complex diseases and health conditions such as type 2 diabetes (T2D).
arxiv +1 more source
Plant sterols and stanols are structurally similar to cholesterol and when added to the diet they are able to reduce serum total- and LDL-cholesterol concentrations.
Marleen Schonewille+4 more
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