Results 81 to 90 of about 487,969 (369)

Self‐Healing Hydrogel Dressing with Solubilized Flavonoids for Whole Layer Regeneration of Diabetic Wound

Advanced Healthcare Materials, EarlyView.
High glucose‐ and acid‐responsive hydrogel with dynamic covalent bond solubilized with flavonoids (Gel‐Flavonoids) is designed for diabetic wound healing. The Gel‐Flavonoids adapt to irregular wound shapes and release antioxidants in high‐glucose environments, effectively reducing reactive oxygen species.
Qiang Zeng, Sa Du, Rui Yuan, Yuan Zeng, Xuefen Li, Yu‐Wei Wu, Ke Chen, Lei Tao, Zhihui Tang, Xuliang Deng   +9 more
wiley   +1 more source

Effects of ethanol on the metabolism of free fatty acids in isolated liver cells

Journal of Lipid Research, 1973
Ethanol inhibited the oxidation and enhanced the esterification of albumin-bound [1-14C]palmitate incubated with isolated rat liver cells. Ethanol decreased the conversion of [1-14C]palmitate to 14CO2 and 14C-labeled ketone bodies and enhanced the ...
Joseph A. Ontko
doaj  

BEEF TALLOW AND EMULSIFIER IN GROWING-FINISHING PIG DIETS

Anais da Academia Brasileira de Ciências
Two trials were aimed to evaluate beef tallow in diets with and without emulsifier on performance of pigs at growing-finishing phases. In the first trial, 15 barrows (22.03±0.62 kg) were distributed among three treatments: reference diet; test diet 1 (5%
KASSIA M. SANTOS, PEDRO H. WATANABE, EDNARDO R. FREITAS, RAFAEL C. NEPOMUCENO, PAULA J.D. OLIVEIRA, VIRGÍNIA M. LIMA, BÁRBARA B.V. RODRIGUES, GERMANO A.J. DO NASCIMENTO, LUIZ E. DE CARVALHO   +8 more
doaj   +1 more source

RNF112 Facilitates Ubiquitin‐Mediated Degradation of c‐Myc, Suppressing Proliferation, Migration and Lipid Synthesis in Bladder Cancer

Advanced Science, EarlyView.
RNF112, an E3 ubiquitin ligase, is markedly reduced in bladder cancer (BLCA). It curbs BLCA cell proliferation, migration, and lipid production primarily by enhancing ubiquitin‐dependent degradation of c‐Myc. This degradation inhibits c‐Myc's role in upregulating ACLY, a crucial enzyme for lipid synthesis, highlighting RNF112's potential as a ...
Kangping Xiong, Siming Chen, Huimin Xu, Sheng Tu, Hong Weng, Yejinpeng Wang, Mingxing Li, Jingtian Yu, Kaiyu Qian, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Gang Wang   +13 more
wiley   +1 more source

Increased concentrations of circulating vitamin E in carriers of the apolipoprotein A5 gene −1131T>C variant and associations with plasma lipids and lipid peroxidation

Journal of Lipid Research, 2007
The aim of this study was to investigate the effects of the apolipoprotein A5 (APOA5) 1131T>C gene variant on vitamin E status and lipid profile. The gene variant was determined in 297 healthy nonsmoking men aged 20–75 years and recruited in the VITAGE ...
Isabella Sundl, Montse Guardiola, Gholamali Khoschsorur, Rosa Solà, Joan C. Vallvé, Gemma Godàs, Lluís Masana, Michaela Maritschnegg, Andreas Meinitzer, Nicolas Cardinault, Johannes M. Roob, Edmond Rock, Brigitte M. Winklhofer-Roob, Josep Ribalta   +13 more
doaj  

Observation of Cholesterol Dissolved in Microscopic Deposits of Free Fatty Acids in the Lumen of an Aorta of a Mouse Model for Human Atherosclerosis [PDF]

SPIE 7 5321A-11 (2004), 2008
The Raman spectrum of microscopic droplets of lipid material on the lumen of the aorta of an apolipoprotein E knock-out mouse were reported in the proceedings of an SPIE conference. Based on the absence of the carbonyl band in the spectrum, at that time it was determined that the spectrum represents free fatty acids rather than triglycerides.
arxiv  

Neuropeptide Ecdysis‐Triggering Hormone and Its Receptor Mediate the Fecundity Improvement of ‘Candidatus Liberibacter Asiaticus’‐Infected Diaphorina citri Females and CLas Proliferation

Advanced Science, EarlyView.
In CLas‐infected D. citri, CLas lowers 20E levels initially, relieving the suppression of ETH release. The subsequent increase in ETH levels upregulates its receptor DcETHR and activates the JH signaling pathway. The signaling cascade of 20E‐ETH/ETHR‐JH along with miR‐210, targeting DcETHR, boost female fecundity in CLas+ D.
Xiaoge Nian, Bo Wang, Paul Holford, George Andrew Charles Beattie, Shijian Tan, Weiwei Yuan, Yijing Cen, Yurong He, Songdou Zhang   +8 more
wiley   +1 more source

Prevalence and Pattern of Dyslipidemia and Its Associated Factors Among Patients with Type 2 Diabetes Mellitus in Jordan: A Cross-Sectional Study

International Journal of General Medicine, 2022
Thekraiat M Al Quran,1 Ziad A Bataineh,2 Abdel-Hameed Al-Mistarehi,1 Anas M Zein Alaabdin,1 Hadeel Allan,1 Anood Al Qura’an,3 Shatha M Weshah,1 Anfal A Alanazi,4 Yousef S Khader1 1Department of Public Health and Family Medicine, Faculty of Medicine ...
Al Quran TM, Bataineh ZA, Al-Mistarehi AH, Zein Alaabdin AM, Allan H, Al Qura'an A, Weshah SM, Alanazi AA, Khader YS   +8 more
doaj  

Genome analysis and pleiotropy assessment using causal networks with loss of function mutation and metabolomics [PDF]

arXiv, 2019
Background: Many genome-wide association studies have detected genomic regions associated with traits, yet understanding the functional causes of association often remains elusive. Utilizing systems approaches and focusing on intermediate molecular phenotypes might facilitate biologic understanding.
arxiv  

A Bayesian method for estimating gene-level polygenicity under the framework of transcriptome-wide association study [PDF]

arXiv, 2022
Polygnicity refers to the phenomenon that multiple genetic variants have a non-zero effect on a complex trait. It is defined as the proportion of genetic variants that have a nonzero effect on the trait. Evaluation of polygenicity can provide valuable insights into the genetic architecture of the trait.
arxiv