Results 91 to 100 of about 415 (104)

Moderate increase in dietary fat induces alterations of microbiota and metabolome along the digestive tract prior to systemic metabolic changes: insights from a pig model. [PDF]

Gut Microbes
Ranson A, Vazquez Gomez M, Alili R, Durrafourd J, Vitalis O, Taillandier P, Rebière C, Merabtene F, Belda E, Crespo-Piazuelo D, Gonzalez-Bulnes A, Marcelin G, Mardinoglu A, Chikh K, Le Roy T, Clément K.   +15 more
europepmc   +1 more source

Complement System and Adhesion Molecule Skirmishes in Fabry Disease: Insights into Pathogenesis and Disease Mechanisms. [PDF]

Int J Mol Sci
Magnusen AF, Pandey MK.
europepmc   +1 more source

Oral Prodrug of a Novel Glutathione Surrogate Reverses Metabolic Dysregulation and Attenuates Neurodegenerative Process in Transgenic Alzheimer's Mice. [PDF]

ACS Pharmacol Transl Sci
Rao SP, Imam-Fulani AO, Xie W, Phillip S, Chennavajula K, Bhilare KD, Lind EB, Zhang Y, Vince R, Lee MK, More SS.   +10 more
europepmc   +1 more source

Trihexosylceramide α-galactosidase of human leucocytes

Clinica Chimica Acta, 1978
Trihexosylceramide, isolated from human kidney and labelled in the terminal galactose position by oxidation with galactose oxidase and reduction with sodium boro[3H]hydride, was used to study some of the properties of human leucocyte alpha-galactosidase. The enzyme was inactive in the absence of detergent.
A, Poulos, K, Beckman
openaire   +3 more sources

The structure of canine intestinal trihexosylceramide

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1979
One of the neutral glycosphingolipids isolated from dog intestine has a mobility on thin-layer chromatography and a carbohydrate composition similar to trihexosylceramides. Structural analysis has shown that it consists largely of isoglobotriaosylceramide, galactosyl(alpha-1-3)galactosyl(beta-1-4)glucosyl(beta 1-1')ceramide.
S S, Sung, C C, Sweeley
openaire   +3 more sources

Structure of trihexosylceramide biosynthesized in vitro by rat kidney galactosyltransferase

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1974
Abstract Trihexosylceramide biosynthesized in vitro from lactosylceramide and UDPgalactose in the presence of galactosyltransferase from rat kidney microsomes was shown by permethylation to consist of two positional isomers in which the galactopyranosyl units are linked 1 → 3 and 1→ 4, respectively.
A, Stoffyn, P, Stoffyn, G, Hauser
openaire   +3 more sources

A female heterozygous patient with fabry's disease with renal accumulation of trihexosylceramide detected with a monoclonal antibody

American Journal of Kidney Diseases, 1995
We describe a female patient with heterozygous Fabry's disease. The patient had persistent proteinuria and microhematuria but lacked any other diagnostic signs such as corneal and cutaneous involvement. Kidney tissue obtained at biopsy showed the segmentally distributed enlarged glomerular epithelia.
M, Fukushima, Y, Tsuchiyama, T, Nakato, T, Yokoi, H, Ikeda, S, Yoshida, T, Kusumoto, K, Itoh, H, Sakuraba   +8 more
openaire   +3 more sources

Immunofluorescence analysis of trihexosylceramide accumulated in the hearts of variant hemizygotes and heterozygotes with Fabry disease

The American Journal of Cardiology, 1996
An immunofluorescence method was applied to detect trihexosylceramide accumulated in the cardiac tissues from a variant hemizygote and a heterozygous female with Fabry disease, the incidence of which had been suspected to be high.
K, Itoh, T, Takenaka, S, Nakao, M, Setoguchi, H, Tanaka, T, Suzuki, H, Sakuraba   +6 more
openaire   +3 more sources

Biosynthesis of globoside and forssman hapten from trihexosylceramide and properties of β-N-acetyl-galactosaminyltransferase of guinea pig kidney

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1974
Abstract The enzyme(s) that catalyze the transfer of N -acetylgalactosamine from UDP - N -acetylgalactosamine to exogenous human kidney galactosyl-galactosyl-glucosylceramide was detected in young guinea pig tissues. The enzymatic products from trihexosylceramide were identified as globoside and Forssman hapten by thin-layechromatography, chemical ...
T, Ishibashi, S, Kijimoto, A, Makita
openaire   +3 more sources

[Crystalline morphology of trihexosylceramide deposits characteristic of Fabry's disease (notably the rheumatic form)].

Comptes rendus des seances de la Societe de biologie et de ses filiales, 1981
This paper deals with the various crystalline aspects of the ceramide trihexoside (CTH) inclusions, in the synovial tissue essentially. A basic classification is proposed and uncommon examples are illustrated. Image processing confirms the membrane-like structure of CTH inclusions and corroborates the proposed classification.
S, Laoussadi, H, Dupoisot, A, Constans, G, Daury, F, Delbarre   +4 more
openaire   +2 more sources