Plasma Sphingolipids Associated with Chronic Obstructive Pulmonary Disease Phenotypes
, 2015 Rationale: Chronic obstructive pulmonary disease (COPD) occurs in a minority of smokers and is characterized by intermittent exacerbations and clinical subphenotypes such as emphysema and chronic bronchitis.
Charlotte Siska +9 more
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Role of Sphingolipids in the Pathobiology of Lung Inflammation [PDF]
Sphingolipid bioactivities in the respiratory airways and the roles of the proteins that handle them have been extensively investigated. Gas or inhaled particles or microorganisms come into contact with mucus components, epithelial cells, blood barrier ...
Anna Caretti +2 more
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Utilising proteomics-derived data to identify novel biomarker signatures in Multiple Myeloma. [PDF]
Multiple myeloma (MM) is characterized by the clonal expansion of plasma cells in the bone marrow that results in end-organ damage, including hypercalcemia, renal dysfunction, infection, anemia, and bone disease.
Dunphy, Katie
core
Analyse omique de la variabilité interindividuelle de la réponse à la consommation de framboises chez des sujets présentant des désordres métaboliques : la relation hôte-microbiote dans le développement du syndrome métabolique [PDF]
La mise en évidence de l'association entre désordres métaboliques et état dysbiotique remet aujourd'hui en cause la définition et les modes de traitement traditionnels du syndrome métabolique.
Franck, Maximilien Christophe
core +1 more source
The second report of a new hypomyelinating disease due to a defect in the gene discloses a massive lysosomal involvement [PDF]
core +1 more source
, 1996 The epidemic form of the hemolytic uremic syndrome (HUS) has been associated with a verocytotoxin producing Escherichia coli infection. Endothelial cell damage of glomeruli and arterioles of the kidney plays a central role in the pathogenesis of HUS.
Heuvel, L.P.W.J. van den +4 more
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Sphingolipid and Glycosphingolipid Metabolic Pathways in the Era of Sphingolipidomics [PDF]
, 2011 Merrill, Alfred H.
core +2 more sources
Correction: Chaby et al. Cross-Platform Evaluation of Commercially Targeted and Untargeted Metabolomics Approaches to Optimize the Investigation of Psychiatric Disease. <i>Metabolites</i> 2021, <i>11</i>, 609. [PDF]
Metabolites, 2023 Chaby LE +8 more
europepmc +1 more source
Historical Control Analysis Demonstrates Greater Long-Term Reduction in Plasma Globotriaosylceramide (Gb3) by Venglustat Compared With Placebo or Agalsidase Beta in Male Patients With Classic Fabry Disease. [PDF]
Mol Genet Genomic MedGermain DP +6 more
europepmc +1 more source