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Trihexyphenidyl Use Disorder and Withdrawal Syndrome
Journal of Psychiatry Spectrum, 2023 Tanve Garg, Vikram Singh Rawat
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Trihexyphenidyl hydrochloride: a powder diffraction study [PDF]
Acta Crystallographica Section E Structure Reports Online, 2010 IN THE CATION OF THE TITLE COMPOUND [SYSTEMATIC NAME: 1-(3-cyclo-hexyl-3-hy-droxy-3-phenyl-prop-yl)piperidinium chloride], C(20)H(32)NO(+)·Cl(-), the cyclo-hexyl and piperidine rings are in chair conformations. In the crystal structure, cations and anions are linked into chains along the c-axis direction via O-H⋯Cl and N-H⋯Cl hydrogen bonds. Weak inter-
Maccaroni E. +2 more
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Treatment of Dystonia Using Trihexyphenidyl in Costello Syndrome [PDF]
Brain Sciences, 2020 Costello syndrome (CS), a rare syndrome with multisystemic involvement inherited as a dominant trait, is characterized by developmental delay, coarse facial appearance, cardiac defects including hypertrophic cardiomyopathy, skin abnormalities, brain complications, and a predisposition to certain malignancies.
Romeo D. M. +7 more
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Trihexyphenidyl Misuse in Delusional Disorder [PDF]
Journal of Neurosciences in Rural Practice, 2018 ABSTRACTTrihexyphenidyl is an anticholinergic medication that is routinely used for the management of extrapyramidal symptoms in patients who receive antipsychotic medications. Trihexyphenidyl has been reported to be abused by some patients, who start to take it in increasing doses and tend to report a sensation of relaxation or pleasure with this ...
Ananya Mahapatra +4 more
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Trihexyphenidyl for dystonia in cerebral palsy [PDF]
Cochrane Database of Systematic Reviews, 2018 Cerebral palsy occurs in up to 2.1 of every 1000 live births and encompasses a range of motor problems and movement disorders. One commonly occurring movement disorder amongst those with cerebral palsy is dystonia: sustained or intermittent involuntary muscle spasms and contractions that cause twisting, repetitive movements and abnormal postures.
Katrina Williams +8 more
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Inclusion complexes of trihexyphenidyl with natural and modified cyclodextrins [PDF]
SpringerPlus, 2015 Abstract The solubility of trihexyphenidyl (Thp) was improved by its combination with β-cyclodextrin (β−CD) and modified β-CDs. The solubility of Thp was found to be increased in the presence of β-CD, hydroxypropyl-β-cyclodextrin (HP-β-CD), methyl-β-cyclodextrin (Me-β-CD) and sulfobutylether-β-cyclodextrin (SBE-β-CD).
Hirokazu Nakayama +2 more
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IMPAIRED ABSORPTION OF CHLORPROMAZINE IN RATS GIVEN TRIHEXYPHENIDYL [PDF]
British Journal of Pharmacology, 1976 The absorption and tissue distribution of orally administered [14C]‐chlorpromazine (CPZ) were compared in trihexyphenidyl (THP; Artane)‐treated and control rats. Total radioactivity (CPZ) in the plasma and brain of rats treated with THP was significantly lower whereas total radioactivity in the stomach was significantly higher than in rats not ...
Leonor Rivera‐Calimlim
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Simultaneous Spectrophotometric Estimation of Haloperidol and Trihexyphenidyl in Tablets
Indian Journal of Pharmaceutical Sciences, 2010 The combination of haloperidol and trihexyphenidyl is a dosage form to be used as antidyskinetic agent. Literature revealed that there is no single method for the simultaneous estimation of these drugs in tablet dosage form, which prompted us to develop a simple, rapid, accurate, economical and sensitive spectrophotometric method.
AA Borkar, SP Wate
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Successful Use of Risperidone, Trihexyphenidyl, and Paroxetine in Pregnancy
Indian Journal of Psychological Medicine, 2017 Sandeep Kumar Goyal, Atul Goel
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Misuse of trihexyphenidyl: Factors associated to the prescription
European Psychiatry, 2016 IntroductionTrihexyphenidyl (THP) is an anti-Parkison and anticholinergic drug. It is essentially prescribed by psychiatrists in order to treat abnormal movements and Parkinsonism induced by antipsychotics. However, in unusual practice, the THP is widely used by patients.AimsTo assess different factors associated to the prescription of trihexyphenidyl ...
N. mohamed +4 more
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