Beyond anticholinergic effects: A case of trihexyphenidyl-induced bradycardia [PDF]
Journal of Family Medicine and Primary CareAnticholinergic drugs are extensively employed in clinical settings, with their side effects well-documented. However, paradoxical bradycardia due to trihexyphenidyl hydrochloride, an anticholinergic agent, is an infrequent and underreported phenomenon ...
Soumi Kundu +6 more
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Development and Characterization of Trihexyphenidyl Orodispersible Minitablets: A Challenge to Fill the Therapeutic Gap in Neuropediatrics [PDF]
PharmaceuticsBackground: Trihexyphenidyl (THP) has been widely used for over three decades as pediatric pharmacotherapy in patients affected by segmental and generalized dystonia.
Camila Olivera +7 more
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Crystal structures of four organic salts of trihexyphenidyl at 90 K [PDF]
Acta Crystallographica Section E: Crystallographic Communications, 2023 The syntheses and crystal structure studies of four organic salts of trihexyphenidyl, viz., trihexyphenidylium [1-(3-cyclohexyl-3-hydroxy-3-phenylpropyl)piperidin-1-ium] 4-nitrobenzoate, C20H32NO+·C7H4NO4− (I), trihexyphenidylium 4-hydroxybenzoate ...
Vinaya +3 more
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A cross sectional study of trihexyphenidyl utilization on patient receiving antipsychotic therapy [PDF]
JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2016 Background: Psychotic disorder becomes a mental health problem recently that reduce quality of life of the patient. As the matter of fact, psychotic treatment induce another problem such as extrapyramidal symtomps (EPS).
Addiniya Nurul Azmi, Sufi Desrini
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A Novel Reduced Graphene Oxide Modified Carbon Paste Electrode for Potentiometric Determination of Trihexyphenidyl Hydrochloride in Pharmaceutical and Biological Matrices [PDF]
Sensors, 2021 A novel promising carbon paste electrode with excellent potentiometric properties was prepared for the analysis of trihexyphenidyl hydrochloride (THP), the acetylcholine receptor and an anticholinergic drug in real samples.
Josip Radić +4 more
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STUDI RETROSPEKTIF PENGGUNAAN TRIHEXYFENIDIL PADA PASIEN SKIZOFRENIA RAWAT INAP YANG MENDAPAT TERAPI ANTIPSKOTIK DI RUMAH SAKIT JIWA SAMBANG LIHUM [PDF]
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy), 2016 Trihexyphenidyl (THP) is used to treat symptoms of Parkinson's disease or involuntary movements due to the side effects of certain psychiatric drugs. It can also decrease other side effects such as muscle stiffness/rigidity (extrapyramidal syndrome or ...
Anggie Rahaya, Noor Cahaya
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Trihexyphenidyl triggered hypomania in a bipolar patient
Psychiatry and Behavioral Sciences, 2012 We observed a case of tardive dyskinesia after regular use of low dose chlorpromazine. An anticholinergic agent; trihexyphenidyl (THX) was used to treat the tardive dyskinesia.
Eren Yıldızhan +3 more
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Formulation and evaluation of bi-layer floating tablets of ziprasidone HCl and trihexyphenidyl HCl [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2011 The purpose of this research study was to establish ziprasidone HCl NR 40 mg and trihexyphenidyl HCl SR 4mg in the form of bi-layer sustained release floating tablets.
Sathis Kumar Dinakaran +4 more
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Behavioral signature of trihexyphenidyl in the TOR1A (DYT1) knockin mouse model of dystonia [PDF]
DystoniaDystonia is a neurological disorder characterized by involuntary repetitive movements and abnormal postures. Animal models have played a pivotal role in studying the pathophysiology of dystonia.
Ahmad Abdal Qader +8 more
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Muscarinic receptor drug trihexyphenidyl can alter growth of mesenchymal glioblastoma in vivo [PDF]
Frontiers in PharmacologyGlioblastoma (GBM) is the most commonly occurring and most aggressive primary brain tumor. Transcriptomics-based tumor subtype classification has established the mesenchymal lineage of GBM (MES-GBM) as cancers with particular aggressive behavior and high
Renfei Du +18 more
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