Results 31 to 40 of about 4,933 (206)

Administration of Atropine Eye Drops Sublingually for Clozapine-Induced Sialorrhea in Bipolar Disorder [PDF]

BJPsych Open
Aims The aim of this study is to explore the off-label use of atropine, administered sublingually, for the management of clozapine-induced sialorrhea in a patient who showed inadequate response to commonly used agents.
Shaurya Garg, Amit Kumar, Omar Afroz, Preethy Kathiresan, Raman Deep   +4 more
doaj   +2 more sources

Trihexyphenidyl rescues the deficit in dopamine neurotransmission in a mouse model of DYT1 dystonia

Neurobiology of Disease, 2019
Trihexyphenidyl, a nonselective muscarinic receptor antagonist, is the small molecule drug of choice for the treatment of DYT1 dystonia, but it is poorly tolerated due to significant side effects.
Anthony M. Downs, Xueliang Fan, Christine Donsante, H.A. Jinnah, Ellen J. Hess   +4 more
doaj   +3 more sources

Centrally acting anticholinergic drug trihexyphenidyl is highly effective in reducing nightmares associated with post‐traumatic stress disorder

Brain and Behavior, 2021
Introduction Following a case study on scopolamine butyl bromide, an anticholinergic drug, we studied the effect of a central anticholinergic drug on post‐traumatic stress disorder (PTSD)‐related flashbacks and nightmares.
Katsumasa Sogo, Masanobu Sogo, Yoshie Okawa   +2 more
doaj   +2 more sources

The clinical characteristics, putative drugs, and optimal management of 62 patients with stevens-johnson syndrome and/or toxic epidermal necrolysis: A retrospective observational study

Indian Dermatology Online Journal, 2022
Background: Case reviews of severe cutaneous adverse drug reactions (ADRs) such as SJS/TEN provide useful insights for clinical characteristics, putative drugs, and management protocols.
Sujaya Manvi, Vikram K Mahajan, Karaninder S Mehta, Pushpinder S Chauhan, Sanket Vashist, Ravinder Singh, Prabal Kumar   +6 more
doaj   +1 more source

Serum short-chain fatty acids and its correlation with motor and non-motor symptoms in Parkinson’s disease patients

BMC Neurology, 2022
Background Parkinson’s disease (PD) is associated with enteric nervous system dysfunction and gut microbiota dysbiosis. Short-chain fatty acids (SCFAs), derived from gut microbiota, are supposed to anticipate PD pathogenesis via the pathway of spinal ...
Gang Wu, Zhengli Jiang, Yaling Pu, Shiyong Chen, Tingling Wang, Yajing Wang, Xiaoping Xu, Shanshan Wang, Minya Jin, Yangyang Yao, Yang Liu, Shaofa Ke, Suzhi Liu   +12 more
doaj   +1 more source

Clinical Presentation and Management of Acute Dystonia from Drug Abuse or Misuse in Adolescents and Young Adults: A Retrospective Cohort Study in Bangkok, Thailand

Emergency Medicine International, 2023
Objectives. To describe the clinical presentation of acute dystonia (AD) from drug abuse or misuse, as well as the emergency department (ED) management and outcomes in adolescents and young adults. Methods.
Pootipong Wongveerasin, Rittirak Othong, Akkasil Pinchumponsang, Warunya Hungspruke, Peerarin Jongjaroenwit   +4 more
doaj   +1 more source

A case of overdose of fluphenazine decanoate injection

Open Journal of Psychiatry and Allied Sciences, 2022
Case description: A 28 years old, married Hindu male from a tea garden community, working as daily wage earner was diagnosed as a case of schizophrenia, paranoid type from psychiatry outpatient department (OPD) of Tezpur Medical College and Hospital ...
Barasha Saharia, Soumitra Ghosh
doaj   +1 more source

[Changes in Test Methods for Internationalization in the Japanese Pharmacopoeia (Part 3): Establishment of a Quantitative Method for Sodium Cromoglicate and Trihexyphenidyl Hydrochloride Using HPLC Analysis].

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2023
The Japanese Pharmacopoeia (JP) is an official normative publication for establishing the authenticity and properties and maintaining the quality of pharmaceutical products in Japan.
Genichiro Tsuji, T. Ito, N. Uchiyama, J. Hosoe, Yosuke Demizu, Y. Goda   +5 more
semanticscholar   +1 more source

Levodopa Dose-Limiting Dyskinesias in Treatment of Segawa Disease

Pediatric Neurology Briefs, 2012
Researchers at the University of Cordoba, and other centers in Spain, Germany and New York report an atypical phenotype of persistent, low-dose levodopa treatment-limiting dyskinesias in 2 members of a family (female child aged 13 years and mother) with ...
J Gordon Millichap
doaj   +1 more source

Catatonia: A rare presentation of Wilson's disease

Industrial Psychiatry Journal, 2021
Wilson's disease (WD) or hepatolenticular degeneration is a rare inherited disorder of copper metabolism affecting both the liver and the central nervous system.
Supriya Davis, Jwalant Chag, Salesh Rohatgi, Suprakash Chaudhury, Daniel Saldanha   +4 more
doaj   +1 more source