The corticotropin‐releasing factor (CRF) system plays a key role in centrally regulating thyroid hormone (TH) synthesis in non‐mammalian vertebrates, but interactions between THs and the CRF system remain poorly understood in fish. Here, we report that THs directly affect transcription of several CRF system components across different hypophysiotropic ...
Brett M. Culbert+2 more
wiley +1 more source
Pituitary hyperplasia mimicking macroadenoma associated with primary hypothyroidism in a patient with selective L-thyroxine malabsorption [PDF]
We present the case of a 29-year-old woman who developed a severe hypothyroidism induced by a thyroxine malabsorption and a secondary pituitary hyperplasia.
Romanelli, Francesco+4 more
core +1 more source
Tibetan sheep are indigenous to the Qinghai-Tibetan Plateau (QTP) and are well-adapted to and even thrive under the harsh alpine conditions. Small-tailed Han sheep were introduced to the plateau because of their high prolificacy and are maintained mainly
Degen, A.A.+14 more
core +1 more source
A skin explant model for studying UV‐induced DNA damage and repair
The study describes an ex vivo skin model that preserves the natural physiology of the skin while addressing ethical concerns related to animal research. We demonstrate this model maintains key characteristics and physiological responses of in vivo skin during short incubation periods. Moreover, this model requires fewer mice than in vivo testing, thus
Hailey Payne+3 more
wiley +1 more source
Autoantibodies to thyroxin and triiodothyronine.
Abstract Two clinically euthyroid patients with multinodular goiter were found to have high "free" thyroxin (Amerlex-M, Amersham and Coat-a-Count, DPC) and triiodothyronine (Amerlex-M) concentrations (FT4 and FT3, respectively). The presence of antibodies to T4 and T3 was confirmed by the finding that polyethylene glycol precipitated a ...
M. C. Rajput+5 more
openaire +3 more sources
This study evaluated the association between baseline thyroid hormones levels, sensitivity index and the incidence of AMS in 70 healthy individuals traveling from Beijing (44 m above sea level) to Lhasa (3650 m above sea level). The dataset was divided into a training set (n = 56) and a validation set (n = 14) at an ratio of 8:2.
Cencen Wu+13 more
wiley +1 more source
Comparative aspects of resistance to body-cooling in newborn lambs and kids : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Animal Science at Massey University [PDF]
THE PROBLEM OF PERINATAL MORTALITY IN LAMBS AND KIDS Fibre-producing goats are becoming an increasingly important species on New Zealand farms. There is a considerable lack of information about the physiology of goats, especially as it relates to the ...
Müller, Sabine
core
Comparative Effects of DL-Thyronine, L-Triiodothyronine and L-Thyroxine on the Isolated Perfused Frog Heart [PDF]
Morris Kleinfeld+2 more
openalex +1 more source
Elevated cortisol concentration in preterm sheep fetuses impacts heart development
Abstract The prepartum rise in cortisol promotes cardiac development and maturation. Here, we investigated the impact of elevated circulating cortisol during mid‐late gestation on cardiac growth and metabolism in fetal sheep. Saline or cortisol (2–3 mg in 4.4 mL/24 h) was infused into the fetal jugular vein from 109 to 116 days gestation (dG, term ...
Reza Amanollahi+9 more
wiley +1 more source
An In Vitro Effect of Triiodothyronine on Rat Adipose Tissue* [PDF]
Martha Vaughan
openalex +1 more source