Results 91 to 100 of about 42,910 (268)

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Thyroid Hormone Supplementation Restores Cognitive Deficit, Insulin Signaling, and Neuroinflammation in the Hippocampus of a Sporadic Alzheimer’s-like Disease Rat Model

open access: yesCells
Thyroid hormones play a crucial role in the development of the central nervous system and are considered pivotal to cognitive functions in the adult brain. Recently, thyroid dysfunction has been associated with Alzheimer’s disease.
Paulina Sepúlveda   +6 more
doaj   +1 more source

Thyroid function tests in cases of polymorphic light eruption: A case-control study

open access: yesIndian Dermatology Online Journal, 2014
Background: Polymorphic light eruption (PLE) has been found to be associated with thyroid function abnormalities. Aim: To study clinicoepidemiological features of PLE and to study and compare thyroid function tests (TFTs) in cases of PLE.
Lata Sharma, Sachin Lamba, S K Singh
doaj   +1 more source

Oral triiodothyronine in the perioperative management of central hypothyroidism

open access: yes, 2007
Oral triiodothyronine (T3) has never been described in literature as a major form of perioperative therapy. This series highlights the role of oral triiodothyronine in the perioperative management of patients with overt hypothyroidism for semi-urgent ...
Khan, D.   +5 more
core  

The Effects of Cyclophosphamide on the Pharmacokinetics of Triiodothyronine in the Male Rat

open access: yes, 1996
In the present study, the possibility that cyclophosphamide or a cyclophosphamide metabolite may be accelerating the clearance of triiodothyronine has been examined.
Lloyd N Sansom   +3 more
core   +1 more source

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve   +6 more
wiley   +1 more source

Brown Adipose Tissue: An Extrathyroidal Source of Triiodothyronine

open access: yes, 1986
The role of brown adipose tissue in heat production is well known, but it is a novel concept that this tissue can activate the main secretory product of the thyroid gland, thyroxine, by converting it into the ten times more active triiodothyronine.
JE Silva
core   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha (Withania somnifera)

open access: yesPhytotherapy Research, EarlyView.
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan   +2 more
wiley   +1 more source

Performa produksi Broiler starter akibat cekaman panas dan perbedaan awal waktu pemberian pakan

open access: yesJurnal Ilmu-Ilmu Peternakan, 2018
The study was conducted to know performance (feed consumption, body weight gain and feed conversion) response of broiler starter due to heat stress and different initial feeding.
Liborio Ximenes   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy