Results 111 to 120 of about 47,368 (266)

Brown Adipose Tissue: An Extrathyroidal Source of Triiodothyronine

open access: yes, 1986
The role of brown adipose tissue in heat production is well known, but it is a novel concept that this tissue can activate the main secretory product of the thyroid gland, thyroxine, by converting it into the ten times more active triiodothyronine.
JE Silva
core   +1 more source

A Year in the Bones: Investigating Bone Resorption Across a Reproductive Year in Wild Female Assamese Macaques

open access: yesJournal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Reproduction places considerable metabolic demands on females, particularly during pregnancy and lactation, when calcium homeostasis and bone metabolism are challenged. Urinary C‐terminal telopeptide of type I collagen (CTX‐I) offers a useful non‐invasive marker to assess bone resorption.
Verena Behringer   +6 more
wiley   +1 more source

Hyperthyroxinaemia due to decreased peripheral triiodothyronine production [PDF]

open access: yes, 1982
Two patients, a boy of 8 and a woman of 60 years of age, had higher than normal levels of serum total thyroxine (T4), free T4 (FT4), FT4 index, and reverse triiodothyronine, but normal serum triiodothyronine (T3) levels.
Docter, R.   +6 more
core  

Relative Potencies of Thyroxine and Triiodothyronine Based on Various Criteria in Thiouracil-Treated Chickens

open access: yes, 1957
Relative sensitivities of various criteria, which were found to be suitable qualitative indicators of thyroxine and triiodothyronine, were determined by calculating and comparing the amounts of each hormone necessary to maintain the control level of ...
W. S. Newcomer
core   +1 more source

Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat [PDF]

open access: yes, 2002
Earlier studies at our laboratory indicated that several hydroxylated polychlorinated biphenyls (OH-PCBs) detected in human blood could specifically inhibit thyroxine (T4) transport by competitive binding to the thyroid hormone transport protein ...
Bergman, A.   +11 more
core   +2 more sources

Metabolic pattern across energy imbalance: An exploratory metabolomics study of female body weight extremes including anorexia nervosa and athletes

open access: yesExperimental Physiology, EarlyView.
Abstract In anorexia nervosa (AN), prolonged metabolic adaptation to severe energy deficiency can impair treatment efficacy. Similarly, low energy availability poses a recognized risk to athletes, potentially compromising health and performance. This cross‐sectional study aimed to characterize the plasma metabolic pattern of females with varying ...
Sonja Lackner   +6 more
wiley   +1 more source

Triiodothyronine (T3) induces HIF1A and TGFA expression in MCF7 cells by activating PI3K

open access: yes, 2016
High expression levels of hypoxia inducing factor 1 alpha are related to mammary carcinogenesis. In previous studies, we demonstrated that expression of transforming growth factor alpha increases upon treatment with triiodothyronine, but this expression ...
Moretto, Fernanda Cristina Fontes   +15 more
core   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter   +4 more
wiley   +1 more source

Disrupted thyroid hormone homeostasis in critical illness: clinical correlates and associations with hormone supplementation in a single-center retrospective observational study

open access: yesAnaesthesiology Intensive Therapy
Background Thyroid hormone disturbances are a hallmark of critical illness and are commonly attributed to non-thyroidal illness syndrome. The clinical relevance of thyroid hormone supplementation in the intensive care unit (ICU) remains uncertain.
Alicja Filipczyk   +7 more
doaj   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer   +2 more
wiley   +1 more source

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