Results 111 to 120 of about 34,365 (231)

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, Volume 15, Issue 27, 17 July 2026.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, Volume 13, Issue 39, 13 July 2026.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, Volume 13, Issue 37, 3 July 2026.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Adrenal insufficiency influences the pattern of thyrotoxicosis toward triiodothyronine predominance. [PDF]

JCEM Case Rep
Maruoka A, Nishimura K, Mukai C, Takahashi K, Irie J, Toyoda N.   +5 more
europepmc   +1 more source

Analytical and Workflow Performance of a High‐Throughput Chemiluminescent Immunoassay System in a Clinical Laboratory

Journal of Clinical Laboratory Analysis, Volume 40, Issue 13, July 2026.
Analytical and operational performance evaluation of the DxI 9000 Access Immunoassay Analyzer in a clinical laboratory in Taiwan. ABSTRACT Background Increasing test volumes and shorter turnaround time (TAT) requirements, particularly in acute‐care settings, challenge clinical laboratories to maintain accurate immunoassay testing.
Chiung‐Tzu Hsiao, Chao‐Ching Liao, Yu‐Chang Chang, Hui‐Ju Chang, Tz‐Ya Huang, Jen‐Shiou Lin, Po‐Ren Hsueh   +6 more
wiley   +1 more source

Low thyroid hormone status as a cardiovascular risk factor: A cross-sectional study from NHANES 2007-2012. [PDF]

Medicine (Baltimore)
Yu S, Zhang G, Li H.
europepmc   +1 more source

Taste and Smell Disturbances Associated With Secondary Adrenal Insufficiency: A Case Report

Journal of General and Family Medicine, Volume 27, Issue 4, July 2026.
ABSTRACT Background Adrenal insufficiency often presents with nonspecific symptoms, impeding early diagnosis. Taste and smell disturbances are rarely recognized as presenting features. Case Presentation We report the case of a 54‐year‐old man with a 3‐month history of persistent taste and smell disturbances accompanied by fatigue, loss of appetite ...
Takanori Izumi, Eri Doi, Yuki Tsutsui, Noboru Horinouchi, Rie Utsunomiya, Katsuhiko Yoshimura, Machiko Morita, Naoki Matsuda, Seiji Shiota   +8 more
wiley   +1 more source

Associations of thyroid hormones with metabolic syndrome and coronary artery stenosis in euthyroid individuals: A cross-sectional study. [PDF]

Medicine (Baltimore)
Guo M, Liu C, Lv D, Lin Q, Zhang A, Cai P.   +5 more
europepmc   +1 more source

The Lipid Droplet–Associated Hydrolase Is Associated With Obesity and Adipose Tissue Inflammation in Children

Obesity, Volume 34, Issue 7, Page 1420-1432, July 2026.
ABSTRACT Objective The lipid droplet–associated hydrolase (LDAH) is a lipid droplet–associated protein with an uncharacterized role in human adipose tissue (AT) and obesity; we aimed to investigate its role in human AT and its relevance for childhood obesity.
Claudia Vales‐Villamarín, Antje Berthold, Martin Lacher, Antje Körner, Kathrin Landgraf   +4 more
wiley   +1 more source

Isotretinoin and serum thyroid parameters: systematic review and meta-analysis. [PDF]

An Bras Dermatol
Mostafa N, Hong E, Stewart T.
europepmc   +1 more source